Proximal tubule haptoglobin gene activation is an integral component of the acute kidney injury "stress response". (Q36200275)

12 August 2017

Proximal tubule haptoglobin gene activation is an integral component of the acute kidney injury "stress response". (English)

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12 August 2017

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Richard A Zager

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12 August 2017

Anitha Vijayan

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2

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12 August 2017

Ali C M Johnson

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3

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12 August 2017

9 May 2012

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American Journal of Physiology - Renal Physiology

12 August 2017

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12 August 2017

303

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12 August 2017

1

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12 August 2017

F139-48

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Recovery from glycerol-induced acute kidney injury is accelerated by suramin

12 August 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431141

Haptoglobin activates innate immunity to enhance acute transplant rejection in mice.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431141

MicroRNA-18a enhances the interleukin-6-mediated production of the acute-phase proteins fibrinogen and haptoglobin in human hepatocytes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431141

Acute unilateral ischemic renal injury induces progressive renal inflammation, lipid accumulation, histone modification, and "end-stage" kidney disease

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431141

Hypoxia-inducible factor-1alpha enhances haptoglobin gene expression by improving binding of STAT3 to the promoter

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431141

Renal cortical albumin gene induction and urinary albumin excretion in response to acute kidney injury

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431141

Endogenous IL-10 attenuates cisplatin nephrotoxicity: role of dendritic cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431141

Mechanisms regulating repression of haptoglobin production by peroxisome proliferator-activated receptor-gamma ligands in adipocytes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431141

Sequestration of extracellular hemoglobin within a haptoglobin complex decreases its hypertensive and oxidative effects in dogs and guinea pigs

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431141

Haptoglobin halts hemoglobin's havoc

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431141

Haptoglobin, inflammation and disease

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431141

Hypothesis--haptoglobin genotype and diabetic nephropathy

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431141

In vivo and in vitro studies establishing haptoglobin as a major susceptibility gene for diabetic vascular disease

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431141

Haptoglobin phenotypes in health and disorders

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431141

Ischemic acute renal failure: an inflammatory disease?

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431141

HAPTOGLOBIN SYNTHESIS. I. IN VIVO STUDIES OF THE PRODUCTION OF HAPTOGLOBIN, FIBRINOGEN, AND GAMMA-GLOBULIN BY THE CANINE LIVER

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431141

Haptoglobin interacts with the human mast cell line HMC-1 and inhibits its spontaneous proliferation.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431141

Phospholipase A2 activity can protect renal tubules from oxygen deprivation injury

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431141

Haptoglobin synthesis. II. Cellular localization studies

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431141

Aberrant protein expression in plasma and kidney tissue during experimental obstructive nephropathy.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431141

Haptoglobin polymorphism as a risk factor for chronic kidney disease: a case-control study.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431141

Haptoglobin deficiency facilitates the development of autoimmune inflammation.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431141

Haptoglobin polymorphism and diabetic nephropathy in Brazilian diabetic patients

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431141

Haptoglobin genotype determines myocardial infarct size in diabetic mice

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431141

Haptoglobin dampens endotoxin-induced inflammatory effects both in vitro and in vivo.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431141

Antioxidant role of human haptoglobin

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431141

Haptoglobin therapy for possible prevention of renal failure following thermal injury: a clinical study

22 September 2018

1 reference

12 December 2020

STAT3/NF-κB interactions determine the level of haptoglobin expression in male rats exposed to dietary restriction and/or acute phase stimuli

1 reference

12 December 2020

Studies of hepatic synthesis in vivo of plasma proteins, including orosomucoid, transferrin, alpha 1-antitrypsin, C8, and factor B

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12 December 2020

Human haptoglobin binds to human myoglobin

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12 December 2020

Haptoglobin directly affects T cells and suppresses T helper cell type 2 cytokine release

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12 December 2020

Haptoglobin and the Th1/Th2 balance: hints from in vitro and in vivo studies

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12 December 2020

Human haptoglobin structure and function - a molecular modelling study

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12 December 2020

Acute renal failure: determinants and characteristics of the injury-induced hyperinflammatory response

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12 December 2020

The carboxyl-terminal region of STAT3 controls gene induction by the mouse haptoglobin promoter

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12 December 2020

The protective influence of haptoglobin on hemoglobinuric kidney. II. Microscopic observations and clinical aspect

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12 December 2020

Haptoglobin reduces renal oxidative DNA and tissue damage during phenylhydrazine-induced hemolysis

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12 December 2020

Heme and the Vasculature: an Oxidative Hazard that Induces Antioxidant Defenses in the Endothelium

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12 December 2020

Association between haptoglobin gene variants and diabetic nephropathy: haptoglobin polymorphism in nephropathy susceptibility

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12 December 2020

10.1152/AJPRENAL.00168.2012

Identifiers

DOI

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12 August 2017

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12 August 2017

PubMed publication ID

22573378

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