The inverted free energy landscape of an intrinsically disordered peptide by simulations and experiments (Q36205942)

12 August 2017

The inverted free energy landscape of an intrinsically disordered peptide by simulations and experiments (English)

1 reference

12 August 2017

1 reference

8

Michele Vendruscolo

1 reference

12 August 2017

Celine Galvagnion

4

0 references

Carlo Camilloni

object named as

Carlo Camilloni

6

0 references

Alessandro Laio

object named as

Alessandro Laio

7

0 references

author name string

Daniele Granata

1

1 reference

12 August 2017

Fahimeh Baftizadeh

2

1 reference

12 August 2017

Johnny Habchi

3

1 reference

12 August 2017

Alfonso De Simone

5

1 reference

12 August 2017

language of work or name

English

0 references

publication date

26 October 2015

1 reference

12 August 2017

1 reference

12 August 2017

5

1 reference

12 August 2017

15449

1 reference

Creative Commons Attribution 4.0 International

12 August 2017

start time

26 October 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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1 October 2017

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Temperature-dependent solvation modulates the dimensions of disordered proteins

1 October 2017

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Identification of small-molecule binding pockets in the soluble monomeric form of the Aβ42 peptide

1 October 2017

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Aβ monomers transiently sample oligomer and fibril-like configurations: ensemble characterization using a combined MD/NMR approach

1 October 2017

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Characterization of the free-energy landscapes of proteins by NMR-guided metadynamics

1 October 2017

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A decade and a half of protein intrinsic disorder: biology still waits for physics

1 October 2017

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Insights into Aβ aggregation: a molecular dynamics perspective

1 October 2017

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Describing sequence-ensemble relationships for intrinsically disordered proteins

1 October 2017

1 reference

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The protein-folding problem, 50 years on.

1 October 2017

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Intrinsically disordered proteins: a 10-year recap

1 October 2017

1 reference

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A preformed binding interface in the unbound ensemble of an intrinsically disordered protein: evidence from molecular simulations

1 October 2017

1 reference

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Structure of an intermediate state in protein folding and aggregation

1 October 2017

1 reference

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Experimental free energy surfaces reveal the mechanisms of maintenance of protein solubility

1 October 2017

1 reference

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Ensemble modeling of protein disordered states: experimental restraint contributions and validation

1 October 2017

1 reference

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Understanding the structural ensembles of a highly extended disordered protein

1 October 2017

1 reference

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Homogeneous and heterogeneous tertiary structure ensembles of amyloid-β peptides.

1 October 2017

1 reference

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Compaction properties of an intrinsically disordered protein: Sic1 and its kinase-inhibitor domain

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620491

Constructing ensembles for intrinsically disordered proteins

1 October 2017

1 reference

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Atomic-level characterization of the ensemble of the Aβ(1-42) monomer in water using unbiased molecular dynamics simulations and spectral algorithms

1 October 2017

1 reference

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SPARTA+: a modest improvement in empirical NMR chemical shift prediction by means of an artificial neural network

1 October 2017

1 reference

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Understanding protein non-folding.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620491

Determination of the free energy landscape of alpha-synuclein using spin label nuclear magnetic resonance measurements

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620491

Single-molecule spectroscopy of the temperature-induced collapse of unfolded proteins

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620491

Quantitative determination of the conformational properties of partially folded and intrinsically disordered proteins using NMR dipolar couplings

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620491

A facile method for expression and purification of the Alzheimer's disease-associated amyloid beta-peptide

1 October 2017

1 reference

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Dynamic equilibrium engagement of a polyvalent ligand with a single-site receptor

1 October 2017

1 reference

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Atomic-level characterization of disordered protein ensembles

1 October 2017

1 reference

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Determination of conformationally heterogeneous states of proteins

1 October 2017

1 reference

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Elucidating amyloid beta-protein folding and assembly: A multidisciplinary approach

1 October 2017

1 reference

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A structural model for unfolded proteins from residual dipolar couplings and small-angle x-ray scattering.

1 October 2017

1 reference

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Heat capacity in proteins

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620491

Intrinsically unstructured proteins and their functions

1 October 2017

1 reference

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A structural model for Alzheimer's beta -amyloid fibrils based on experimental constraints from solid state NMR

1 October 2017

1 reference

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Intrinsically unstructured proteins

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620491

Escaping free-energy minima

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620491

Charge states rather than propensity for beta-structure determine enhanced fibrillogenesis in wild-type Alzheimer's beta-amyloid peptide compared to E22Q Dutch mutant

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620491

Protein Structure and the Energetics of Protein Stability.

1 October 2017

1 reference

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What does it mean to be natively unfolded?

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620491

From folding theories to folding proteins: a review and assessment of simulation studies of protein folding and unfolding

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620491

Estimation of protein secondary structure from circular dichroism spectra: comparison of CONTIN, SELCON, and CDSSTR methods with an expanded reference set

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620491

Understanding protein folding via free-energy surfaces from theory and experiment

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620491

Canonical dynamics: Equilibrium phase-space distributions

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620491

Temperature dependence of amyloid beta-protein fibrillization

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620491

Solution structure of amyloid beta-peptide(1-40) in a water-micelle environment. Is the membrane-spanning domain where we think it is?

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620491

Theory of protein folding: the energy landscape perspective

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620491

From Levinthal to pathways to funnels

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620491

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

1 October 2017

1 reference

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Funnels, pathways, and the energy landscape of protein folding: a synthesis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620491

Structure of amyloid A4-(1-40)-peptide of Alzheimer's disease

1 October 2017

1 reference

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Cold denaturation of proteins

1 October 2017

1 reference

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The Energy Landscapes and Motions of Proteins

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620491

Effects of familial mutations on the monomer structure of Aβ₄₂.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620491

How robust are protein folding simulations with respect to force field parameterization?

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620491

Amyloid beta-protein monomer structure: a computational and experimental study.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620491

Hydrodynamic radii of native and denatured proteins measured by pulse field gradient NMR techniques.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620491

A lysozyme folding intermediate revealed by solution X-ray scattering.

29 June 2018

1 reference

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P-LINCS: A Parallel Linear Constraint Solver for Molecular Simulation.

29 June 2018

1 reference

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Single-molecule spectroscopy of cold denaturation and the temperature-induced collapse of unfolded proteins

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620491

Carnosine inhibits Aβ(42) aggregation by perturbing the H-bond network in and around the central hydrophobic cluster

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620491

Temperature-dependent structural changes in intrinsically disordered proteins: formation of alpha-helices or loss of polyproline II?

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620491

Solution NMR studies of the A beta(1-40) and A beta(1-42) peptides establish that the Met35 oxidation state affects the mechanism of amyloid formation

22 September 2018

1 reference

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Use of fast protein size-exclusion liquid chromatography to study the unfolding of proteins which denature through the molten globule

22 September 2018

1 reference

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PLUMED: A portable plugin for free-energy calculations with molecular dynamics

22 September 2018

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Mapping Long-Range Interactions in α-Synuclein using Spin-Label NMR and Ensemble Molecular Dynamics Simulations

21 January 2018

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Distinct Morphologies for Amyloid Beta Protein Monomer: Aβ1–40, Aβ1–42, and Aβ1–40(D23N)

21 January 2018

1 reference

The effects of guanidine hydrochloride on the 'random coil' conformations and NMR chemical shifts of the peptide series GGXGG

21 January 2018

1 reference

Protein Folding and Ligand-Enzyme Binding from Bias-Exchange Metadynamics Simulations

21 January 2018

1 reference

Reversible Random Coil to β-Sheet Transition and the Early Stage of Aggregation of the Aβ(12−28) Fragment from the Alzheimer Peptide

21 January 2018

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Protein thermodynamics: Are native proteins metastable?

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26498066

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SREP15449

1 reference

Dimensions Publication ID

12 August 2017

0 references

1 reference

12 August 2017

PubMed publication ID

26498066

1 reference