The impact of interferon lambda 3 gene polymorphism on natural course and treatment of hepatitis C (Q36208380)

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12 February 2020

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26 October 2022

The impact of interferon lambda 3 gene polymorphism on natural course and treatment of hepatitis C (English)

1 reference

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single-nucleotide polymorphism

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14 September 2019

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3 November 2019

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20 November 2019

1

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Gaetano Serviddio

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2

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language of work or name

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27 August 2012

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14 September 2019

3 November 2019

20 November 2019

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1 July 2020

22 October 2022

25 October 2022

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Clinical and Developmental Immunology

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3 November 2019

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Creative Commons Attribution 3.0 Unported

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1 October 2017

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IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy

1 October 2017

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Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C

1 October 2017

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Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance

1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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Interferons alpha and lambda inhibit hepatitis C virus replication with distinct signal transduction and gene regulation kinetics

1 October 2017

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Interleukin-29 uses a type 1 interferon-like program to promote antiviral responses in human hepatocytes

1 October 2017

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Id2 leaves the chromatin of the E2F4-p130-controlled c-myc promoter during hepatocyte priming for liver regeneration

1 October 2017

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Lambda interferon (IFN-lambda), a type III IFN, is induced by viruses and IFNs and displays potent antiviral activity against select virus infections in vivo

1 October 2017

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Review article: chronic hepatitis C--natural history and cofactors

1 October 2017

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Global epidemiology of hepatitis C virus infection

1 October 2017

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Lambda interferon inhibits hepatitis B and C virus replication

1 October 2017

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Peginterferon alfa-2b and ribavirin for the treatment of chronic hepatitis C in blacks and non-Hispanic whites

1 October 2017

1 reference

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Viral infection and Toll-like receptor agonists induce a differential expression of type I and lambda interferons in human plasmacytoid and monocyte-derived dendritic cells

1 October 2017

1 reference

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IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex

1 October 2017

1 reference

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IL-28, IL-29 and their class II cytokine receptor IL-28R

1 October 2017

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Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection

1 October 2017

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Current and future treatment of hepatitis C.

1 October 2017

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Preclinical and clinical development of pegylated interferon-lambda 1 in chronic hepatitis C.

1 October 2017

1 reference

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Phase 1b study of pegylated interferon lambda 1 with or without ribavirin in patients with chronic genotype 1 hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

IL-28A is a key regulator of T-cell-mediated liver injury via the T-box transcription factor T-bet.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

Hepatic ISG expression is associated with genetic variation in interleukin 28B and the outcome of IFN therapy for chronic hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

An IL28B polymorphism determines treatment response of hepatitis C virus genotype 2 or 3 patients who do not achieve a rapid virologic response

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

Prediction of response to pegylated interferon plus ribavirin by IL28B gene variation in patients coinfected with HIV and hepatitis C virus.

21 January 2018

1 reference

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Importance of IL28B gene polymorphisms in hepatitis C virus genotype 2 and 3 infected patients

21 January 2018

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IL28B polymorphism is associated with treatment response in patients with genotype 4 chronic hepatitis C.

21 January 2018

1 reference

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Effect of IL28B genotype on early viral kinetics during interferon-free treatment of patients with chronic hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

A polymorphism near IL28B is associated with spontaneous clearance of acute hepatitis C virus and jaundice

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

Impact of donor and recipient IL28B rs12979860 genotypes on hepatitis C virus liver graft reinfection

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

Recipient IL28B polymorphism is an important independent predictor of posttransplant diabetes mellitus in liver transplant patients with chronic hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

Predictive value of the IL28B polymorphism on the effect of interferon therapy in chronic hepatitis C patients with genotypes 2a and 2b.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

Meta-analysis: IL28B polymorphisms predict sustained viral response in HCV patients treated with pegylated interferon-α and ribavirin

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

Variants in IL28B in liver recipients and donors correlate with response to peg-interferon and ribavirin therapy for recurrent hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

Genotype rs8099917 near the IL28B gene and amino acid substitution at position 70 in the core region of the hepatitis C virus are determinants of serum apolipoprotein B-100 concentration in chronic hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

IL28B alleles associated with poor hepatitis C virus (HCV) clearance protect against inflammation and fibrosis in patients infected with non-1 HCV genotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

IL28B genetic variation and treatment response in patients with hepatitis C virus genotype 3 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

Association between IL28B polymorphisms and first-phase viral load decrease in chronic hepatitis C virus-infected patients treated with peginterferon alfa-2b/ribavirin

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

Association between the IL28B genotype and hepatitis C viral kinetics in the early days of treatment with pegylated interferon plus ribavirin in HIV/HCV co-infected patients with genotype 1 or 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

Hepatitis C virus kinetics in chimeric mice during antiviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

HCV substitutions and IL28B polymorphisms on outcome of peg-interferon plus ribavirin combination therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

IL28B polymorphisms, IP-10 and viral load predict virological response to therapy in chronic hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

Serum level of IP-10 increases predictive value of IL28B polymorphisms for spontaneous clearance of acute HCV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

A single IL28B genotype SNP rs12979860 determination predicts treatment response in patients with chronic hepatitis C Genotype 1 virus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

Do lambda-IFNs IL28A and IL28B act on human natural killer cells?

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

Amino acid substitution in hepatitis C virus core region and genetic variation near the interleukin 28B gene predict viral response to telaprevir with peginterferon and ribavirin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

Hepatitis C viral load, genotype 3 and interleukin-28B CC genotype predict mortality in HIV and hepatitis C-coinfected individuals.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433716

IL28B CC genotype is associated with higher all-cause mortality in antiretroviral-treated HIV-infected patients.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433716

Association between interleukin-28B-related genetic variants and liver histopathology differs between hepatitis C virus genotypes.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433716

Combined effects of different interleukin-28B gene variants on the outcome of dual combination therapy in chronic hepatitis C virus type 1 infection.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433716

Impact of IL28B polymorphisms on response to peginterferon and ribavirin in HIV–hepatitis C virus-coinfected patients with prior nonresponse or relapse

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433716

Genetic variation in IL28B is associated with the development of hepatitis B-related hepatocellular carcinoma

22 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22966241

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1155/2012/849373

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22966241%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22966241%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

PubMed publication ID

22966241

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22966241%20AND%20SRC:MED&resulttype=core&format=json