Disruption of BRD4 at H3K27Ac-enriched enhancer region correlates with decreased c-Myc expression in Merkel cell carcinoma. (Q36213758)

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7 March 2020

title

Disruption of BRD4 at H3K27Ac-enriched enhancer region correlates with decreased c-Myc expression in Merkel cell carcinoma (English)

1 reference

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7 March 2020

main subject

Merkel cell carcinoma

1 reference

1

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7 March 2020

Malan Kern

3

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7 March 2020

author name string

Aarthi Kannan

2

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7 March 2020

Mauricio A Moreno

4

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7 March 2020

Emre Vural

5

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7 March 2020

Brendan Stack

6

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7 March 2020

James Y Suen

7

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7 March 2020

Alan J Tackett

8

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7 March 2020

Ling Gao

9

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7 March 2020

publication date

5 May 2015

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7 March 2020

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7 March 2020

volume

10

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7 March 2020

issue

6

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7 March 2020

page(s)

460-466

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describes a project that uses

7 March 2020

ImageQuant

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11 June 2022

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based on heuristic

inferred from PubMed Central ID database lookup

cites work

Oncogene regulation. An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element

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Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia

1 October 2017

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BET protein inhibitor JQ1 attenuates Myc-amplified MCC tumor growth in vivo

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Control of embryonic stem cell identity by BRD4-dependent transcriptional elongation of super-enhancer-associated pluripotency genes

1 October 2017

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The mechanisms behind the therapeutic activity of BET bromodomain inhibition

1 October 2017

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Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer

1 October 2017

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Targeting bromodomains: epigenetic readers of lysine acetylation

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Enhancer RNAs and regulated transcriptional programs

1 October 2017

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Merkel Cell Carcinoma: Epidemiology, Target, and Therapy

1 October 2017

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Relationships among primary tumor size, number of involved nodes, and survival for 8044 cases of Merkel cell carcinoma

1 October 2017

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Enhancer RNAs: the new molecules of transcription

1 October 2017

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Chronic mTOR activation promotes cell survival in Merkel cell carcinoma

1 October 2017

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Super-enhancers in the control of cell identity and disease

1 October 2017

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Merkel cell polyomavirus small T antigen controls viral replication and oncoprotein expression by targeting the cellular ubiquitin ligase SCFFbw7.

1 October 2017

1 reference

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Selective inhibition of tumor oncogenes by disruption of super-enhancers

1 October 2017

1 reference

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Distinct gene expression profiles of viral- and nonviral-associated merkel cell carcinoma revealed by transcriptome analysis

1 October 2017

1 reference

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Bromodomain-containing protein 4 (BRD4) regulates RNA polymerase II serine 2 phosphorylation in human CD4+ T cells

1 October 2017

1 reference

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Pathologic characteristics of NUT midline carcinoma arising in the mediastinum

1 October 2017

1 reference

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Activation of the PI3K/AKT pathway in Merkel cell carcinoma

1 October 2017

1 reference

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BET bromodomain inhibition as a therapeutic strategy to target c-Myc

1 October 2017

1 reference

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Transcriptome-wide studies of merkel cell carcinoma and validation of intratumoral CD8+ lymphocyte invasion as an independent predictor of survival.

1 October 2017

1 reference

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Selective inhibition of BET bromodomains

1 October 2017

1 reference

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Histone crosstalk between H3S10ph and H4K16ac generates a histone code that mediates transcription elongation

1 October 2017

1 reference

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Control of inducible gene expression by signal-dependent transcriptional elongation

1 October 2017

1 reference

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Array-CGH reveals recurrent genomic changes in Merkel cell carcinoma including amplification of L-Myc

1 October 2017

1 reference

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1 October 2017

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Merkel cell polyomavirus status is not associated with clinical course of Merkel cell carcinoma.

1 October 2017

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Transcription: Enhancers make non-coding RNA.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622756

10.1080/15592294.2015.1034416

22 September 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25941994%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25941994%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

PubMed publication ID

25941994

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25941994%20AND%20SRC:MED&resulttype=core&format=json