Manipulation of very few receptor discriminator residues greatly enhances receptor specificity of non-visual arrestins (Q36215950)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22787152%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

title

Manipulation of very few receptor discriminator residues greatly enhances receptor specificity of non-visual arrestins (English)

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7 February 2020

4

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7 February 2020

author name string

Luis E Gimenez

series ordinal

1

1 reference

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7 February 2020

Sergey A Vishnivetskiy

series ordinal

2

1 reference

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7 February 2020

Faiza Baameur

series ordinal

3

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7 February 2020

language of work or name

English

0 references

publication date

11 July 2012

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7 February 2020

number of pages

11

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Journal of Biological Chemistry

inferred from page(s)

published in

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7 February 2020

volume

287

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7 February 2020

issue

35

1 reference

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7 February 2020

page(s)

29495-29505

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22787152%20AND%20SRC:MED&resulttype=core&format=json

Silent scaffolds: inhibition OF c-Jun N-terminal kinase 3 activity in cell by dominant-negative arrestin-3 mutant

7 February 2020

cites work

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Identification of arrestin-3-specific residues necessary for JNK3 kinase activation

1 October 2017

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Few residues within an extensive binding interface drive receptor interaction and determine the specificity of arrestin proteins

1 October 2017

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Crystal Structure of Arrestin-3 Reveals the Basis of the Difference in Receptor Binding Between Two Non-visual Subtypes

1 October 2017

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1 October 2017

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Arrestin-1 expression level in rods: balancing functional performance and photoreceptor health

1 October 2017

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Ligand-induced internalization and recycling of the human neuropeptide Y2 receptor is regulated by its carboxyl-terminal tail

1 October 2017

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Custom-designed proteins as novel therapeutic tools? The case of arrestins

1 October 2017

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The role of arrestin alpha-helix I in receptor binding

1 October 2017

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G protein-coupled receptor kinase-2 constitutively regulates D2 dopamine receptor expression and signaling independently of receptor phosphorylation

1 October 2017

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G protein-coupled receptor kinase-mediated phosphorylation regulates post-endocytic trafficking of the D2 dopamine receptor.

1 October 2017

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How and why do GPCRs dimerize?

1 October 2017

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Functional specialization of beta-arrestin interactions revealed by proteomic analysis

1 October 2017

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Arrestin mobilizes signaling proteins to the cytoskeleton and redirects their activity.

1 October 2017

1 reference

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Beta-arrestins and cell signaling

1 October 2017

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Arrestins: ubiquitous regulators of cellular signaling pathways

1 October 2017

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Differential interaction of spin-labeled arrestin with inactive and active phosphorhodopsin

1 October 2017

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The structural basis of arrestin-mediated regulation of G-protein-coupled receptors

1 October 2017

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The differential engagement of arrestin surface charges by the various functional forms of the receptor

1 October 2017

1 reference

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Dynamics of receptor/G protein coupling in living cells

1 October 2017

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Real-time monitoring of receptor and G-protein interactions in living cells.

1 October 2017

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Mutant G-protein-coupled receptors as a cause of human diseases

1 October 2017

1 reference

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Preferential Interaction between the dopamine D2 receptor and Arrestin2 in neostriatal neurons

1 October 2017

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Molecular mechanisms of ligand binding, signaling, and regulation within the superfamily of G-protein-coupled receptors: molecular modeling and mutagenesis approaches to receptor structure and function

1 October 2017

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The molecular acrobatics of arrestin activation

1 October 2017

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Mapping the arrestin-receptor interface. Structural elements responsible for receptor specificity of arrestin proteins

1 October 2017

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The nature of the arrestin x receptor complex determines the ultimate fate of the internalized receptor

1 October 2017

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Differential roles of arrestin-2 interaction with clathrin and adaptor protein 2 in G protein-coupled receptor trafficking

1 October 2017

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Scaffolding functions of arrestin-2 revealed by crystal structure and mutagenesis

1 October 2017

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Arrestin2 and arrestin3 are differentially expressed in the rat brain during postnatal development

1 October 2017

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Crystal structure of beta-arrestin at 1.9 A: possible mechanism of receptor binding and membrane Translocation

1 October 2017

1 reference

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beta-Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking

1 October 2017

1 reference

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Threonine 180 is required for G-protein-coupled receptor kinase 3- and beta-arrestin 2-mediated desensitization of the mu-opioid receptor in Xenopus oocytes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436164

Differential affinities of visual arrestin, beta arrestin1, and beta arrestin2 for G protein-coupled receptors delineate two major classes of receptors

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436164

The 2.8 A crystal structure of visual arrestin: a model for arrestin's regulation

1 October 2017

1 reference

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The beta2-adrenergic receptor/betaarrestin complex recruits the clathrin adaptor AP-2 during endocytosis

1 October 2017

1 reference

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Characterization of dominant negative arrestins that inhibit beta2-adrenergic receptor internalization by distinct mechanisms

1 October 2017

1 reference

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Agonist-receptor-arrestin, an alternative ternary complex with high agonist affinity.

1 October 2017

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A beta-arrestin/green fluorescent protein biosensor for detecting G protein-coupled receptor activation

1 October 2017

1 reference

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Mechanism of quenching of phototransduction. Binding competition between arrestin and transducin for phosphorhodopsin.

1 October 2017

1 reference

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Beta-arrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptor

1 October 2017

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Polypeptide variants of beta-arrestin and arrestin3

1 October 2017

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Phosphodiesterase activation by photoexcited rhodopsin is quenched when rhodopsin is phosphorylated and binds the intrinsic 48-kDa protein of rod outer segments

1 October 2017

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Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family

1 October 2017

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Enhanced arrestin facilitates recovery and protects rods lacking rhodopsin phosphorylation

1 October 2017

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How does arrestin respond to the phosphorylated state of rhodopsin?

29 June 2018

1 reference

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Targeted construction of phosphorylation-independent beta-arrestin mutants with constitutive activity in cells

29 June 2018

1 reference

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Visual arrestin interaction with rhodopsin. Sequential multisite binding ensures strict selectivity toward light-activated phosphorylated rhodopsin.

29 June 2018

1 reference

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Determinants of alpha 2-adrenergic receptor activation of G proteins: evidence for a precoupled receptor/G protein state

29 June 2018

1 reference

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Arrestin interactions with G protein-coupled receptors. Direct binding studies of wild type and mutant arrestins with rhodopsin, beta 2-adrenergic, and m2 muscarinic cholinergic receptors.

29 June 2018

1 reference

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Topographic study of arrestin using differential chemical modifications and hydrogen/deuterium exchange

29 June 2018

1 reference

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Apparent precoupling of kappa- but not mu-opioid receptors with a G protein in the absence of agonist

29 June 2018

1 reference

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Modulation of bovine aortic alpha-2 receptors by Na+, 5'-guanylylimidodiphosphate, amiloride and ethylisopropylamiloride: evidence for receptor G-protein precoupling.

29 June 2018

1 reference

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Elucidation of inositol hexaphosphate and heparin interaction sites and conformational changes in arrestin-1 by solution nuclear magnetic resonance.

29 June 2018

1 reference

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Novel genetically encoded biosensors using firefly luciferase

22 September 2018

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Crystal structure of cone arrestin at 2.3A: evolution of receptor specificity.

22 September 2018

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Dopamine D1 receptor interaction with arrestin3 in neostriatal neurons.

22 September 2018

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Transition of arrestin into the active receptor-binding state requires an extended interdomain hinge

22 September 2018

1 reference

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Conservation of the phosphate-sensitive elements in the arrestin family of proteins

22 September 2018

1 reference

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Interactions of metarhodopsin II. Arrestin peptides compete with arrestin and transducin.

22 September 2018

1 reference

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The selectivity of visual arrestin for light-activated phosphorhodopsin is controlled by multiple nonredundant mechanisms

22 September 2018

1 reference

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Visual arrestin binding to rhodopsin. Diverse functional roles of positively charged residues within the phosphorylation-recognition region of arrestin.

22 September 2018

1 reference

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Cell-free expression of visual arrestin. Truncation mutagenesis identifies multiple domains involved in rhodopsin interaction

22 September 2018

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12 December 2020

Mechanism of phosphorylation-recognition by visual arrestin and the transition of arrestin into a high affinity binding state

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12 December 2020

Use of bacteriophage RNA polymerase in RNA synthesis

1 reference

12 December 2020

Arrestin with a single amino acid substitution quenches light-activated rhodopsin in a phosphorylation-independent fashion

1 reference

12 December 2020

Visualization of agonist-induced sequestration and down-regulation of a green fluorescent protein-tagged beta2-adrenergic receptor

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12 December 2020

Arrestin2 expression selectively increases during neural differentiation

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12 December 2020

A luminescent biosensor with increased dynamic range for intracellular cAMP

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12 December 2020

Identifiers

DOI

10.1074/JBC.M112.366674

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22787152%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22787152%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

PubMed publication ID

22787152

1 reference