An evolutionarily conserved enzyme degrades transforming growth factor-alpha as well as insulin (Q36221404)

12 August 2017

An evolutionarily conserved enzyme degrades transforming growth factor-alpha as well as insulin (English)

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12 August 2017

J V Garcia

1

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12 August 2017

B D Gehm

series ordinal

2

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12 August 2017

M R Rosner

series ordinal

3

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12 August 2017

language of work or name

English

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publication date

1 September 1989

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12 August 2017

7

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inferred from page(s)

published in

Journal of Cell Biology

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12 August 2017

109

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12 August 2017

3

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12 August 2017

1301-1307

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Tumor promoters block tyrosine-specific phosphorylation of the epidermal growth factor receptor

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2115746

Epidermal growth factor-like transforming growth factor. II. Interaction with epidermal growth factor receptors in human placenta membranes and A431 cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2115746

Nucleotide sequence from the neurogenic locus notch implies a gene product that shares homology with proteins containing EGF-like repeats

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2115746

Production of transforming growth factor alpha in human pancreatic cancer cells: evidence for a superagonist autocrine cycle

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2115746

Human recombinant transforming growth factor alpha stimulates bone resorption and inhibits formation in vitro

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2115746

Transformation of normal rat kidney (NRK) cells by an infectious retrovirus carrying a synthetic rat type alpha transforming growth factor gene

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2115746

Developmental regulation of an insulin-degrading enzyme from Drosophila melanogaster

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2115746

Characterization of a Drosophila protein that binds both epidermal growth factor and insulin-related growth factors

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2115746

EGF homologous sequences encoded in the genome of Drosophila melanogaster, and their relation to neurogenic genes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2115746

Human insulin-degrading enzyme shares structural and functional homologies with E. coli protease III

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2115746

Cell-mediated co-action of transforming growth factors: incubation of type beta with normal rat kidney cells produces a soluble activity that prolongs the ruffling response to type alpha

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2115746

Identification of a novel receptor in Drosophila for both epidermal growth factor and insulin

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2115746

Drosophila insulin degrading enzyme and rat skeletal muscle insulin protease cleave insulin at similar sites

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2115746

An insulin epidermal growth factor-binding protein from Drosophila has insulin-degrading activity

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2115746

Inhibition of insulin degradation by hepatoma cells after microinjection of monoclonal antibodies to a specific cytosolic protease

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2115746

A protein extract from Drosophila melanogaster with insulin-like activity

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2115746

Growth factors from murine sarcoma virus-transformed cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2115746

The decapentaplegic gene complex in Drosophila melanogaster.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2115746

Covalent linkage of 125I-insulin to a cytosolic insulin-degrading enzyme.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2115746

Expression in rat fibroblasts of a human transforming growth factor-alpha cDNA results in transformation

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2115746

Isolation and characterization of an insulin-degrading enzyme from Drosophila melanogaster.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2115746

Transforming growth factor-alpha: a more potent angiogenic mediator than epidermal growth factor

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2115746

Isolation of insulin degradation products from endosomes derived from intact rat liver

29 June 2018

1 reference

12 December 2020

Degradation products of insulin generated by hepatocytes and by insulin protease

1 reference

12 December 2020

Purification of denatured epidermal growth factor-receptor from A431 human epidermoid carcinoma cells

1 reference

12 December 2020

Intracellular processing of epidermal growth factor. II. Intracellular cleavage of the COOH-terminal region of 125I-epidermal growth factor

1 reference

12 December 2020

Purification and characterization of insulin-degrading enzyme from human erythrocytes

1 reference

12 December 2020

Epithelial wound healing enhanced by transforming growth factor-alpha and vaccinia growth factor

1 reference

12 December 2020

Identifiers

DOI

10.1083/JCB.109.3.1301

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12 August 2017

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12 August 2017

PubMed publication ID

2670957

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