Cytokine signal transduction is suppressed in preselection double-positive thymocytes and restored by positive selection (Q36227907)

12 August 2017

Cytokine signal transduction is suppressed in preselection double-positive thymocytes and restored by positive selection (English)

1 reference

12 August 2017

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Qing Yu

1

1 reference

12 August 2017

Jung-Hyun Park

2

1 reference

12 August 2017

Loretta L Doan

3

1 reference

12 August 2017

Batu Erman

4

1 reference

12 August 2017

Lionel Feigenbaum

5

1 reference

12 August 2017

Alfred Singer

6

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12 August 2017

language of work or name

English

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publication date

3 January 2006

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Journal of Experimental Medicine

12 August 2017

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12 August 2017

203

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12 August 2017

1

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12 August 2017

165-175

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Regulation of the immune system by SOCS family adaptor proteins

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118084

IL-7 receptor signals inhibit expression of transcription factors TCF-1, LEF-1, and RORgammat: impact on thymocyte development.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118084

In vitro evidence that cytokine receptor signals are required for differentiation of double positive thymocytes into functionally mature CD8+ T cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118084

Interleukin-7: master regulator of peripheral T-cell homeostasis?

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118084

IL-7 is critical for homeostatic proliferation and survival of naive T cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118084

Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118084

Negative regulation of cytokine signaling pathways

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118084

The interleukin 7 receptor is required for T cell receptor gamma locus accessibility to the V(D)J recombinase

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118084

Suppressors of cytokine signaling (SOCS): negative regulators of signal transduction.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118084

Negative regulators of cytokine signal transduction

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118084

Defective development of gamma/delta T cells in interleukin 7 receptor-deficient mice is due to impaired expression of T cell receptor gamma genes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118084

SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118084

Induction of germline transcription in the TCRgamma locus by Stat5: implications for accessibility control by the IL-7 receptor

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118084

Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling-1.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118084

Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118084

Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/- mice

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118084

Expression and function of the interleukin 7 receptor in murine lymphocytes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118084

Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118084

Bcl-2 expression during T-cell development: early loss and late return occur at specific stages of commitment to differentiation and survival

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118084

Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118084

Positive selection of thymocytes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118084

Cytokine production and requirements during T-cell development

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118084

Positive selection of T cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118084

Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118084

Thymocytes between the beta-selection and positive selection checkpoints are nonresponsive to IL-7 as assessed by STAT-5 phosphorylation.

29 June 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20051836

The murine interleukin-2 receptor gamma chain gene: organization, chromosomal localization and expression in the adult thymus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20051836

Suppressor of cytokine signaling-1 is a critical regulator of interleukin-7-dependent CD8+ T cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20051836

IL-7 enhances the survival and maintains the size of naive T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20051836

Suppressor of cytokine signaling 1 is required for the differentiation of CD4+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20051836

The trophic action of IL-7 on pro-T cells: inhibition of apoptosis of pro-T1, -T2, and -T3 cells correlates with Bcl-2 and Bax levels and is independent of Fas and p53 pathways.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118084

Dynamic regulation of IL-7 receptor expression is required for normal thymopoiesis

22 September 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20051836

Coreceptor reversal in the thymus: signaled CD4+8+ thymocytes initially terminate CD8 transcription even when differentiating into CD8+ T cells

21 January 2018

1 reference

12 December 2020

IL-7 is a growth and maintenance factor for mature and immature thymocyte subsets

1 reference

12 December 2020

Expression of the mouse interleukin-2 receptor gamma chain in various cell populations of the thymus and spleen

1 reference

12 December 2020

Bcl-2 is upregulated at the CD4+ CD8+ stage during positive selection and promotes thymocyte differentiation at several control points

1 reference

12 December 2020

Ontogeny and regulation of IL-7-expressing thymic epithelial cells

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20051836

1 reference

12 August 2017

1 reference

12 August 2017

1 reference