Autoreactive marginal zone B cells are spontaneously activated but lymph node B cells require T cell help (Q36228761)

12 August 2017

Autoreactive marginal zone B cells are spontaneously activated but lymph node B cells require T cell help (English)

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12 August 2017

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1 reference

Laura Mandik-Nayak

1

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12 August 2017

Jennifer Racz

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2

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12 August 2017

Barry P Sleckman

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3

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12 August 2017

Paul M Allen

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4

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12 August 2017

language of work or name

English

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publication date

31 July 2006

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Journal of Experimental Medicine

12 August 2017

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12 August 2017

203

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12 August 2017

8

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12 August 2017

1985-1998

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Induction of tolerance in arthritogenic B cells with receptors of differing affinity for self-antigen

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118363

Characterization of marginal zone B cell precursors

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118363

Evidence of marginal-zone B cell-positive selection in spleen

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118363

1 October 2017

Marginal zone B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118363

Critical role of CD4 T cells in an antibody-independent mechanism of vaccination against gammaherpesvirus latency

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118363

Despite ubiquitous autoantigen expression, arthritogenic autoantibody response initiates in the local lymph node

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118363

1 October 2017

Marginal-zone B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118363

Homeostasis of peripheral B cells in the absence of B cell influx from the bone marrow

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118363

The crystal structure of human phosphoglucose isomerase at 1.6 A resolution: implications for catalytic mechanism, cytokine activity and haemolytic anaemia

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118363

Anergy and not clonal ignorance determines the fate of B cells that recognize a physiological autoantigen

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118363

Autoantigen-specific B cell activation in Fas-deficient rheumatoid factor immunoglobulin transgenic mice

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118363

B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118363

MRL-lpr/lpr mice exhibit a defect in maintaining developmental arrest and follicular exclusion of anti-double-stranded DNA B cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118363

From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulins

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118363

Rescue of self-reactive B cells by provision of T cell help in vivo

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118363

Regulation of anti-double-stranded DNA B cells in nonautoimmune mice: localization to the T-B interface of the splenic follicle

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118363

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118363

Anti-red blood cell autoantibody transgenic mice: murine model of autoimmune hemolytic anemia

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118363

1 October 2017

Natural autoantibodies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118363

The fate of self-reactive B cells depends primarily on the degree of antigen receptor engagement and availability of T cell help.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118363

Markedly impaired humoral immune response in mice deficient in complement receptors 1 and 2

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118363

Receptor editing: an approach by autoreactive B cells to escape tolerance

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118363

Receptor editing in self-reactive bone marrow B cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118363

Breakdown of B cell tolerance in a mouse model of systemic lupus erythematosus

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118363

Erythrocyte complement receptor type 1, immune complexes, and the rheumatic diseases

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118363

Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118363

The role of complement in autoimmunity.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118363

Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118363

Small B cells as antigen-presenting cells in the induction of tolerance to soluble protein antigens

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118363

Marginal zone, but not follicular B cells, are potent activators of naive CD4 T cells.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118363

The site and stage of anti-DNA B-cell deletion.

29 June 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060701

Autoreactive B cell regulation: peripheral induction of developmental arrest by lupus-associated autoantigens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060701

Low-affinity anti-Smith antigen B cells are regulated by anergy as opposed to developmental arrest or differentiation to B-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060701

Analysis of marginal zone B cell development in the mouse with limited B cell diversity: role of the antigen receptor signals in the recruitment of B cells to the marginal zone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060701

Reduced life span of anergic self-reactive B cells in a double-transgenic model

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060701

Antigen-induced exclusion from follicles and anergy are separate and complementary processes that influence peripheral B cell fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060701

Split tolerance in peripheral B cell subsets in mice expressing a low level of Igkappa-reactive ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060701

CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060701

Regulation of anti-phosphatidylserine antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060701

IgMhighCD21high lymphocytes enriched in the splenic marginal zone generate effector cells more rapidly than the bulk of follicular B cells.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118363

The impact of T helper and T regulatory cells on the regulation of anti-double-stranded DNA B cells

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118363

Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes

21 October 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060701

Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060701

Induction of self-tolerance in mature peripheral B lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060701

Short-lived plasmablasts dominate the early spontaneous rheumatoid factor response: differentiation pathways, hypermutating cell types, and affinity maturation outside the germinal center

21 January 2018

1 reference

12 December 2020

Arthritis provoked by linked T and B cell recognition of a glycolytic enzyme

1 reference

12 December 2020

Natural autoreactive B cells in transgenic mice reproduce an apparent paradox to the clonal tolerance theory

1 reference

12 December 2020

Lupus-specific antiribonucleoprotein B cell tolerance in nonautoimmune mice is maintained by differentiation to B-1 and governed by B cell receptor signaling thresholds

1 reference

12 December 2020

Anti-Sm B cell differentiation in Ig transgenic MRL/Mp-lpr/lpr mice: altered differentiation and an accelerated response

1 reference

12 December 2020

Marginal zone B cells transport and deposit IgM-containing immune complexes onto follicular dendritic cells

1 reference

12 December 2020

The molecular evolution of the immune response: idiotope-specific suppression indicates that B cells express germ-line-encoded V genes prior to antigenic stimulation

1 reference

12 December 2020

Organ-specific disease provoked by systemic autoimmunity

1 reference

12 December 2020

High affinity rheumatoid factor transgenic B cells are eliminated in normal mice

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20060701

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

16880262

1 reference