Tocilizumab improves the proatherothrombotic profile of rheumatoid arthritis patients modulating endothelial dysfunction, NETosis, and inflammation. (Q36234050)

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English	Tocilizumab improves the proatherothrombotic profile of rheumatoid arthritis patients modulating endothelial dysfunction, NETosis, and inflammation.	scientific article

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Tocilizumab improves the proatherothrombotic profile of rheumatoid arthritis patients modulating endothelial dysfunction, NETosis, and inflammation (English)

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rheumatoid arthritis

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based on heuristic

inferred from title

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based on heuristic

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Mari Carmen Ábalos Aguilera

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Carlos Pérez-Sánchez

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Yolanda Jiménez-Gómez

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Gustavo Ferrín

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Eduardo Collantes Estévez

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Chary López-Pedrera

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author name string

Patricia Ruiz-Limón

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Rafaela Ortega

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Ivan Arias de la Rosa

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Esther Peralbo-Santaella

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Pilar Font

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Desiree Ruiz-Vilches

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Alejandro Escudero-Contreras

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Nuria Barbarroja

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publication date

9 December 2016

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Translational Research

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183

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87-103

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High incidence of cardiovascular events in a rheumatoid arthritis cohort not explained by traditional cardiac risk factors

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7 January 2021

Increased unrecognized coronary heart disease and sudden deaths in rheumatoid arthritis: a population-based cohort study.

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Increased prevalence of severe subclinical atherosclerotic findings in long-term treated rheumatoid arthritis patients without clinically evident atherosclerotic disease

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Inflammation and atherosclerosis

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7 January 2021

Endothelial dysfunction: the early predictor of atherosclerosis.

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7 January 2021

Correlation between endothelial function and carotid atherosclerosis in rheumatoid arthritis patients with long-standing disease

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7 January 2021

Endothelial dysfunction in chronic inflammatory diseases

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7 January 2021

NETs are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritis

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Neutrophil extracellular traps kill bacteria

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Anticyclic citrullinated protein antibodies are implicated in the development of cardiovascular disease in rheumatoid arthritis.

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Monocytes as a diagnostic marker of cardiovascular diseases.

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Macrophages and neutrophils in SLE-An online molecular catalog

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Blood monocyte activation in rheumatoid arthritis: increased monocyte adhesiveness, integrin expression, and cytokine release

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Cells of the synovium in rheumatoid arthritis. Macrophages

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Developments in the scientific understanding of rheumatoid arthritis

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Treatment options in patients with rheumatoid arthritis failing initial TNF inhibitor therapy: a critical review

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A pilot study of endothelial dysfunction and aortic stiffness after interleukin-6 receptor inhibition in rheumatoid arthritis

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Understanding the dynamics: pathways involved in the pathogenesis of rheumatoid arthritis

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Interleukin-17 promotes autoimmunity by triggering a positive-feedback loop via interleukin-6 induction.

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Brief report: inhibition of interleukin-6 function corrects Th17/Treg cell imbalance in patients with rheumatoid arthritis

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7 January 2021

Humanized antihuman IL-6 receptor antibody, tocilizumab

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2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative

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Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis

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A serpinB1 regulatory mechanism is essential for restricting neutrophil extracellular trap generation

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Neutrophil Proteases Promote Experimental Abdominal Aortic Aneurysm via Extracellular Trap Release and Plasmacytoid Dendritic Cell Activation

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Low-density granulocytes: a distinct class of neutrophils in systemic autoimmunity

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Intracellular Signaling Pathways in Rheumatoid Arthritis

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Efficacy and safety of combination therapy for preventing bone damage in rheumatoid arthritis

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Pro-atherogenic lipid changes and decreased hepatic LDL receptor expression by tocilizumab in rheumatoid arthritis.

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7 January 2021

Comparison of lipid and lipid-associated cardiovascular risk marker changes after treatment with tocilizumab or adalimumab in patients with rheumatoid arthritis

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7 January 2021

The Impact of Newer Biological Disease Modifying Anti-Rheumatic Drugs on Cardiovascular Risk Factors: A 12-Month Longitudinal Study in Rheumatoid Arthritis Patients Treated with Rituximab, Abatacept and Tociliziumab

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Lipid profile changes in patients with chronic inflammatory arthritis treated with biologic agents and tofacitinib in randomized clinical trials: a systematic review and meta-analysis

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7 January 2021

Tocilizumab monotherapy reduces arterial stiffness as effectively as etanercept or adalimumab monotherapy in rheumatoid arthritis: an open-label randomized controlled trial

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Study of active controlled tocilizumab monotherapy for rheumatoid arthritis patients with an inadequate response to methotrexate (SATORI): significant reduction in disease activity and serum vascular endothelial growth factor by IL-6 receptor inhibi

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Anti-inflammatory mechanism of tocilizumab, a humanized anti-IL-6R antibody: effect on the expression of chemokine and adhesion molecule

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Etanercept reduces the oxidative stress marker levels in patients with rheumatoid arthritis

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Serum level of oxidative stress marker is dramatically low in patients with rheumatoid arthritis treated with tocilizumab

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Effect of interleukin-6 receptor blockade on surrogates of vascular risk in rheumatoid arthritis: MEASURE, a randomised, placebo-controlled study

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Effects of anti-IL-6 receptor antibody on human monocytes

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Mechanisms and pathologic significances in increase in serum interleukin-6 (IL-6) and soluble IL-6 receptor after administration of an anti-IL-6 receptor antibody, tocilizumab, in patients with rheumatoid arthritis and Castleman disease

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Tyrosine kinases in rheumatoid arthritis

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Enhanced neutrophil extracellular trap generation in rheumatoid arthritis: analysis of underlying signal transduction pathways and potential diagnostic utility.

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Effect of pro-inflammatory cytokines on spontaneous apoptosis in leukocyte sub-sets within a whole blood culture

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Identifiers

10.1016/J.TRSL.2016.12.003

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3 April 2020

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