OSI-930 analogues as novel reversal agents for ABCG2-mediated multidrug resistance (Q36237717)

12 August 2017

OSI-930 analogues as novel reversal agents for ABCG2-mediated multidrug resistance (English)

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12 August 2017

multiple drug resistance

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Ye-Hong Kuang

1

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12 August 2017

Jay P Patel

2

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12 August 2017

Kamlesh Sodani

3

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12 August 2017

Chung-Pu Wu

4

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12 August 2017

Li-Qiu Liao

5

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12 August 2017

Atish Patel

6

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12 August 2017

Amit K Tiwari

7

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12 August 2017

Amit K Tiwari

8

1 reference

12 August 2017

Chun-Ling Dai

9

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12 August 2017

Xiang Chen

10

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12 August 2017

Li-Wu Fu

11

1 reference

12 August 2017

Suresh V Ambudkar

12

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12 August 2017

Vijaya L Korlipara

13

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12 August 2017

Zhe-Sheng Chen

14

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12 August 2017

language of work or name

English

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publication date

28 June 2012

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12 August 2017

Biochemical Pharmacology

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12 August 2017

84

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12 August 2017

6

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12 August 2017

766-774

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describes a project that uses

12 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3443622/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Inhibition of c-Kit, VEGFR-2 (KDR), and ABCG2 by analogues of OSI-930.

1 reference

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1 October 2017

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Inhibiting the function of ABCB1 and ABCG2 by the EGFR tyrosine kinase inhibitor AG1478

1 October 2017

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Lapatinib (Tykerb, GW572016) reverses multidrug resistance in cancer cells by inhibiting the activity of ATP-binding cassette subfamily B member 1 and G member 2

1 October 2017

1 reference

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Erlotinib (Tarceva, OSI-774) antagonizes ATP-binding cassette subfamily B member 1 and ATP-binding cassette subfamily G member 2-mediated drug resistance

1 October 2017

1 reference

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The tyrosine kinase inhibitor imatinib mesylate enhances the efficacy of photodynamic therapy by inhibiting ABCG2.

1 October 2017

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Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins

1 October 2017

1 reference

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OSI-930: a novel selective inhibitor of Kit and kinase insert domain receptor tyrosine kinases with antitumor activity in mouse xenograft models

1 October 2017

1 reference

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Role of the breast cancer resistance protein (ABCG2) in drug transport

1 October 2017

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Evolution of the ATP-binding cassette (ABC) transporter superfamily in vertebrates

1 October 2017

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Imatinib mesylate is a potent inhibitor of the ABCG2 (BCRP) transporter and reverses resistance to topotecan and SN-38 in vitro

1 October 2017

1 reference

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Mutations at amino-acid 482 in the ABCG2 gene affect substrate and antagonist specificity.

1 October 2017

1 reference

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Multidrug resistance reversal agents

1 October 2017

1 reference

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The MRP family of drug efflux pumps

1 October 2017

1 reference

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Considerations in the design and development of transport inhibitors as adjuncts to drug therapy

1 October 2017

1 reference

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Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview.

1 October 2017

1 reference

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Multidrug resistance and cancer: the role of the human ABC transporter ABCG2.

1 October 2017

1 reference

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Multidrug resistance in cancer: role of ATP-dependent transporters

1 October 2017

1 reference

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Mechanisms of cancer drug resistance

1 October 2017

1 reference

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The human ATP-binding cassette (ABC) transporter superfamily

1 October 2017

1 reference

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Multidrug resistance transporters and modulation

1 October 2017

1 reference

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Evidence for a requirement for ATP hydrolysis at two distinct steps during a single turnover of the catalytic cycle of human P-glycoprotein

1 October 2017

1 reference

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Effect of multidrug resistance-reversing agents on transporting activity of human canalicular multispecific organic anion transporter

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443622

Overexpression of the BCRP/MXR/ABCP gene in a topotecan-selected ovarian tumor cell line.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443622

A multidrug resistance transporter from human MCF-7 breast cancer cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443622

Mechanisms of multidrug resistance in human tumor cells. The roles of P-glycoprotein, DNA topoisomerase II, and other factors

1 October 2017

1 reference

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A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443622

Drug-stimulatable ATPase activity in crude membranes of human MDR1-transfected mammalian cells

1 October 2017

1 reference

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Isolation and genetic characterization of human KB cell lines resistant to multiple drugs

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443622

Increased vinblastine binding to membrane vesicles from multidrug-resistant KB cells.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443622

Temporal quantitation of mutant Kit tyrosine kinase signaling attenuated by a novel thiophene kinase inhibitor OSI-930.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443622

Transport of methotrexate, methotrexate polyglutamates, and 17beta-estradiol 17-(beta-D-glucuronide) by ABCG2: effects of acquired mutations at R482 on methotrexate transport.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443622

Potent and specific inhibition of the breast cancer resistance protein multidrug transporter in vitro and in mouse intestine by a novel analogue of fumitremorgin C.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443622

Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil

22 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22750060

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Increased sensitivity to vincristine of MDR cells by the leukotriene D4 receptor antagonist, ONO-1078

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22750060

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BCP.2012.06.019

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

22750060

1 reference