Inhibition of bacterial virulence: drug-like molecules targeting the Salmonella enterica PhoP response regulator (Q36242811)

13 August 2017

Inhibition of bacterial virulence: drug-like molecules targeting the Salmonella enterica PhoP response regulator (English)

1 reference

13 August 2017

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Ann M Stock

5

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Garland R. Marshall

object named as

Garland R Marshall

6

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author name string

Yat T Tang

1

1 reference

13 August 2017

Rong Gao

2

1 reference

13 August 2017

James J Havranek

3

1 reference

13 August 2017

Eduardo A Groisman

4

1 reference

13 August 2017

language of work or name

1 reference

21 March 2012

1 reference

Chemical Biology and Drug Design

13 August 2017

1 reference

13 August 2017

79

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13 August 2017

6

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13 August 2017

1007-1017

1 reference

Molecular strategies for phosphorylation-mediated regulation of response regulator activity

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445336

Biological insights from structures of two-component proteins

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445336

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445336

The PhoQ/PhoP regulatory network of Salmonella enterica

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445336

Targeting QseC signaling and virulence for antibiotic development

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445336

Modulating G-protein coupled receptor/G-protein signal transduction by small molecules suggested by virtual screening

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445336

System-level mapping of Escherichia coli response regulator dimerization with FRET hybrids

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445336

Reaching for high-hanging fruit in drug discovery at protein-protein interfaces

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445336

Crystal Structures of the Receiver Domain of the Response Regulator PhoP from Escherichia coli in the Absence and Presence of the Phosphoryl Analog Beryllofluoride

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445336

Bacterial response regulators: versatile regulatory strategies from common domains

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445336

Virstatin inhibits dimerization of the transcriptional activator ToxT

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445336

A semiempirical free energy force field with charge-based desolvation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445336

A new perspective on response regulator activation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445336

A critical assessment of docking programs and scoring functions

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445336

GFscore: a general nonlinear consensus scoring function for high-throughput docking

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445336

Small-molecule inhibitor of Vibrio cholerae virulence and intestinal colonization

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445336

Structural analysis and solution studies of the activated regulatory domain of the response regulator ArcA: a symmetric dimer mediated by the alpha4-beta5-alpha5 face

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445336

Docking and scoring in virtual screening for drug discovery: methods and applications

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445336

PhoP-regulated Salmonella resistance to the antimicrobial peptides magainin 2 and polymyxin B.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445336

Residue R113 is essential for PhoP dimerization and function: a residue buried in the asymmetric PhoP dimer interface determined in the PhoPN three-dimensional crystal structure

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445336

Further development and validation of empirical scoring functions for structure-based binding affinity prediction

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445336

Principles of docking: An overview of search algorithms and a guide to scoring functions

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445336

Is there a difference between leads and drugs? A historical perspective

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445336

Detailed analysis of scoring functions for virtual screening

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445336

Drug-like properties and the causes of poor solubility and poor permeability

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445336

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445336

The pleiotropic two-component regulatory system PhoP-PhoQ

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445336

The regulatory protein PhoP controls susceptibility to the host inflammatory response in Shigella flexneri

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445336

Two-component signal transduction

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445336

The response regulator PhoP is important for survival under conditions of macrophage-induced stress and virulence in Yersinia pestis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445336

Activated by different signals, the PhoP/PhoQ two-component system differentially regulates metal uptake

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445336

Empirical scoring functions: I. The development of a fast empirical scoring function to estimate the binding affinity of ligands in receptor complexes.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445336

Mg2+ as an extracellular signal: environmental regulation of Salmonella virulence.

29 June 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2012.01362.X

A two-component system is required for colonization of host cells by meningococcus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2012.01362.X

Generation and characterization of a PhoP homologue mutant of Neisseria meningitidis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2012.01362.X

Iterative partial equalization of orbital electronegativity—a rapid access to atomic charges

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2012.01362.X

Assessing scoring functions for protein-ligand interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2012.01362.X

An extensive test of 14 scoring functions using the PDBbind refined set of 800 protein-ligand complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2012.01362.X

Comparative evaluation of 11 scoring functions for molecular docking

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2012.01362.X

Principles of docking: An overview of search algorithms and a guide to scoring functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2012.01362.X

Assessing the performance of OMEGA with respect to retrieving bioactive conformations

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22339993

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Predicting protein-ligand binding affinities: a low scoring game?

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22339993

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/J.1747-0285.2012.01362.X

1 reference

13 August 2017

1 reference

13 August 2017

PubMed publication ID

22339993

1 reference