Gains, losses and complex karyotypes in myeloid disorders: a light at the end of the tunnel (Q36249165)

13 August 2017

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title

Gains, losses and complex karyotypes in myeloid disorders: a light at the end of the tunnel (English)

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13 August 2017

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Sara Alvarez

1

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PubMed ID

16142824

13 August 2017

Juan C Cigudosa

series ordinal

2

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PubMed ID

16142824

13 August 2017

language of work or name

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1 March 2005

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13 August 2017

Hematological Oncology

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13 August 2017

23

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13 August 2017

1

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13 August 2017

18-25

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The World Health Organization classification of neoplasms of the hematopoietic and lymphoid tissues: report of the Clinical Advisory Committee meeting--Airlie House, Virginia, November, 1997.

13 August 2017

1 reference

7 January 2021

1 reference

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The predictive value of hierarchical cytogenetic classification in older adults with acute myeloid leukemia (AML): analysis of 1065 patients entered into the United Kingdom Medical Research Council AML11 trial

1 reference

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Comparative analysis of MLL partial tandem duplication and FLT3 internal tandem duplication mutations in 956 adult patients with acute myeloid leukemia

1 reference

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Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease

1 reference

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Prognostic significance of activating FLT3 mutations in younger adults (16 to 60 years) with acute myeloid leukemia and normal cytogenetics: a study of the AML Study Group Ulm.

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Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha (C/EBPalpha), in acute myeloid leukemia

1 reference

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Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype

1 reference

7 January 2021

Primary vs. secondary neoplasia-associated chromosomal abnormalities--balanced rearrangements vs. genomic imbalances?

1 reference

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Loss of genetic material is more common than gain in acute myeloid leukemia with complex aberrant karyotype: a detailed analysis of 125 cases using conventional chromosome analysis and fluorescence in situ hybridization including 24-color FISH.

1 reference

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Comprehensive genotypic analysis of leukemia: clinical and therapeutic implications

1 reference

7 January 2021

Chromosome and molecular abnormalities in myelodysplastic syndromes

1 reference

7 January 2021

Acute myeloid leukemia

1 reference

7 January 2021

Cytogenetic profile of myelodysplastic syndromes with complex karyotypes: an analysis using spectral karyotyping

1 reference

7 January 2021

Analysis of myelodysplastic syndromes with complex karyotypes by high-resolution comparative genomic hybridization and subtelomeric CGH array

1 reference

7 January 2021

Further characterization of complex chromosomal rearrangements in myeloid malignancies: spectral karyotyping adds precision in defining abnormalities associated with poor prognosis.

1 reference

7 January 2021

Role of multiplex FISH in identifying chromosome involvement in myelodysplastic syndromes and acute myeloid leukemias with complex karyotypes: a report on 28 cases

1 reference

7 January 2021

Identification of cytogenetic subclasses and recurring chromosomal aberrations in AML and MDS with complex karyotypes using M-FISH.

1 reference

7 January 2021

Frequent gain of chromosome 19 in megakaryoblastic leukemias detected by comparative genomic hybridization.

1 reference

7 January 2021

De novo erythroleukemia chromosome features include multiple rearrangements, with special involvement of chromosomes 11 and 19.

1 reference

7 January 2021

Chromosome 19 abnormalities are commonly seen in AML, M7

1 reference

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Multicolor karyotyping in acute myeloid leukemia

1 reference

7 January 2021

Spectral karyotyping in patients with acute myeloid leukemia and a complex karyotype shows hidden aberrations, including recurrent overrepresentation of 21q, 11q, and 22q.

1 reference

7 January 2021

Centromeric breakage and highly rearranged chromosome derivatives associated with mutations of TP53 are common in therapy-related MDS and AML after therapy with alkylating agents: an M-FISH study

1 reference

7 January 2021

Identification of candidate genes on chromosome band 20q12 by physical mapping of translocation breakpoints found in myeloid leukemia cell lines

1 reference

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Structural integrity and expression of the L3MBTL gene in normal and malignant hematopoietic cells

1 reference

7 January 2021

Imprinting of the human L3MBTL gene, a polycomb family member located in a region of chromosome 20 deleted in human myeloid malignancies

1 reference

7 January 2021

Identification of new translocations involving ETV6 in hematologic malignancies by fluorescence in situ hybridization and spectral karyotyping

1 reference

7 January 2021

Comparison of spectral karyotyping and conventional cytogenetics in 39 patients with acute myeloid leukemia and myelodysplastic syndrome

1 reference

7 January 2021

Mutations with loss of heterozygosity of p53 are common in therapy-related myelodysplasia and acute myeloid leukemia after exposure to alkylating agents and significantly associated with deletion or loss of 5q, a complex karyotype, and a poor progno

1 reference

7 January 2021

Acute leukemia cytogenetics: an evaluation of combining G-band karyotyping with multi-color spectral karyotyping

1 reference

7 January 2021

Acute myeloid leukemia with a complex aberrant karyotype is a distinct biological entity characterized by genomic imbalances and a specific gene expression profile

1 reference

7 January 2021

The application of comparative genomic hybridization as an additional tool in the chromosome analysis of acute myeloid leukemia and myelodysplastic syndromes

1 reference

7 January 2021

Expression analyses identify MLL as a prominent target of 11q23 amplification and support an etiologic role for MLL gain of function in myeloid malignancies

1 reference

7 January 2021

Amplification or duplication of chromosome band 21q22 with multiple copies of the AML1 gene and mutation of the TP53 gene in therapy-related MDS and AML

1 reference

7 January 2021

Acute myeloid leukemia with complex karyotypes and abnormal chromosome 21: Amplification discloses overexpression of APP, ETS2, and ERG genes

1 reference

7 January 2021

Expression profiling reveals fundamental biological differences in acute myeloid leukemia with isolated trisomy 8 and normal cytogenetics

1 reference

7 January 2021

Direct evidence of leukocyte adhesion in arterioles by angiotensin II.

1 reference

7 January 2021

Gene expression profiling of pediatric acute myelogenous leukemia

1 reference

7 January 2021

Distinct gene signatures of transient and acute megakaryoblastic leukemia in Down syndrome

1 reference

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Genomic approaches to the pathogenesis of hematologic malignancy

1 reference

7 January 2021

Identifiers

DOI

10.1002/HON.744

1 reference

13 August 2017

1 reference

PubMed ID

16142824