B cells from patients with chronic GVHD are activated and primed for survival via BAFF-mediated pathways (Q36250962)

13 August 2017

B cells from patients with chronic GVHD are activated and primed for survival via BAFF-mediated pathways (English)

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13 August 2017

Jonathan Serody

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Paul M Armistead

object named as

Paul Armistead

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Stefanie Sarantopoulos

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object named as

Stefanie Sarantopoulos

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13 August 2017

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James Coghill

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13 August 2017

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Allison M Deal

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13 August 2017

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Jerome Ritz

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13 August 2017

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Albert S Baldwin

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13 August 2017

Jessica L Allen

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13 August 2017

Matthew S Fore

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13 August 2017

Jenna Wooten

3

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13 August 2017

Philip A Roehrs

4

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13 August 2017

Nazmim S Bhuiya

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13 August 2017

Todd Hoffert

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13 August 2017

Andrew Sharf

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13 August 2017

Don A Gabriel

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13 August 2017

Robert Irons

12

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13 August 2017

Amber Essenmacher

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13 August 2017

Thomas C Shea

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13 August 2017

Kristy Richards

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Corey Cutler

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13 August 2017

language of work or name

English

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publication date

14 August 2012

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13 August 2017

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13 August 2017

2529-2536

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describes a project that uses

13 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3448264/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Prophylactic rituximab after allogeneic transplantation decreases B-cell alloimmunity with low chronic GVHD incidence

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Bone marrow B cell precursor number after allogeneic stem cell transplantation and GVHD development

1 October 2017

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Donor B-cell alloantibody deposition and germinal center formation are required for the development of murine chronic GVHD and bronchiolitis obliterans

1 October 2017

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Recovery of B-cell homeostasis after rituximab in chronic graft-versus-host disease

1 October 2017

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Significant differences in B-cell subpopulations characterize patients with chronic graft-versus-host disease–associated dysgammaglobulinemia

1 October 2017

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Weekly rituximab followed by monthly rituximab treatment for steroid-refractory chronic graft-versus-host disease: results from a prospective, multicenter, phase II study

1 October 2017

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Altered regulatory T cell homeostasis in patients with CD4+ lymphopenia following allogeneic hematopoietic stem cell transplantation.

1 October 2017

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Complement receptor 2/CD21- human naive B cells contain mostly autoreactive unresponsive clones

1 October 2017

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The role of B cells in the pathogenesis of graft-versus-host disease

1 October 2017

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BH3-only proteins and their roles in programmed cell death

1 October 2017

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1 October 2017

Cracking the BAFF code.

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Altered B-cell homeostasis and excess BAFF in human chronic graft-versus-host disease

1 October 2017

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BAFF activates Akt and Erk through BAFF-R in an IKK1-dependent manner in primary mouse B cells

1 October 2017

1 reference

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Effects of donor T-cell trafficking and priming site on graft-versus-host disease induction by naive and memory phenotype CD4 T cells

1 October 2017

1 reference

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Multiple signaling pathways promote B lymphocyte stimulator dependent B-cell growth and survival

1 October 2017

1 reference

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Treatment of refractory chronic GVHD with rituximab: a GITMO study.

1 October 2017

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BAFF controls B cell metabolic fitness through a PKC beta- and Akt-dependent mechanism

1 October 2017

1 reference

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Rituximab for steroid-refractory chronic graft-versus-host disease

1 October 2017

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Loss of the proapoptotic protein, Bim, breaks B cell anergy

1 October 2017

1 reference

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BAFF regulates B cell survival by downregulating the BH3-only family member Bim via the ERK pathway

1 October 2017

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Reduced frequency of FOXP3+ CD4+CD25+ regulatory T cells in patients with chronic graft-versus-host disease

1 October 2017

1 reference

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Identification and characterization of circulating human transitional B cells

1 October 2017

1 reference

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Antibody responses to H-Y minor histocompatibility antigens correlate with chronic graft-versus-host disease and disease remission

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448264

Beginnings of a signal-transduction pathway for bioenergetic control of cell survival

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448264

Extracellular signal-regulated kinases 1/2 are serum-stimulated "Bim(EL) kinases" that bind to the BH3-only protein Bim(EL) causing its phosphorylation and turnover

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448264

Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim inhibits BCR stimulation-induced apoptosis and deletion of autoreactive B cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448264

Antibody response to DBY minor histocompatibility antigen is induced after allogeneic stem cell transplantation and in healthy female donors

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448264

BAFF selectively enhances the survival of plasmablasts generated from human memory B cells.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448264

Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448264

BAFFled B cells survive and thrive: roles of BAFF in B-cell development

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448264

Cell metabolism in the regulation of programmed cell death

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448264

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448264

Bim: a novel member of the Bcl-2 family that promotes apoptosis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448264

Rituximab treatment before reduced-intensity conditioning transplantation associates with a decreased incidence of extensive chronic GVHD.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448264

Cutting edge: the dependence of plasma cells and independence of memory B cells on BAFF and APRIL.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448264

Elevated numbers of immature/transitional CD21- B lymphocytes and deficiency of memory CD27+ B cells identify patients with active chronic graft-versus-host disease.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448264

Mucosal FOXP3+ regulatory T cells are numerically deficient in acute and chronic GvHD.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448264

Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448264

Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFF.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448264

IL-7 enhances the survival and maintains the size of naive T cells

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448264

c-Rel is essential for B lymphocyte survival and cell cycle progression.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448264

Requirement for B cells in T cell priming to minor histocompatibility antigens and development of graft-versus-host disease

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448264

Rituximab as salvage therapy for refractory chronic GVHD

5 December 2018

1 reference

12 December 2020

Cutting edge: CD25+ regulatory T cells prevent expansion and induce apoptosis of B cells specific for tissue autoantigens

1 reference

12 December 2020

Treatment of chronic graft-versus-host disease with anti-CD20 chimeric monoclonal antibody

1 reference

12 December 2020

BAFF/BLyS can potentiate B-cell selection with the B-cell coreceptor complex

1 reference

12 December 2020

10.1182/BLOOD-2012-06-438911

Identifiers

DOI

1 reference

13 August 2017

1 reference

13 August 2017

PubMed publication ID

22896003

1 reference