Activating BRAF and PIK3CA mutations cooperate to promote anaplastic thyroid carcinogenesis (Q36255616)

13 August 2017

Activating BRAF and PIK3CA mutations cooperate to promote anaplastic thyroid carcinogenesis (English)

1 reference

13 August 2017

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Roch-Philippe Charles

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24770869%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Wayne A. Phillips

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24770869%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

author name string

Jillian Silva

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24770869%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Gioia Iezza

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24770869%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Martin McMahon

5

1 reference

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1 June 2020

publication date

25 April 2014

1 reference

Molecular Cancer Research

13 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24770869%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

12

1 reference

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1 June 2020

issue

7

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1 June 2020

page(s)

979-986

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describes a project that uses

1 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4635659/fullTextXML

inferred from PubMed Central ID database lookup

cites work

p53 constrains progression to anaplastic thyroid carcinoma in a Braf-mutant mouse model of papillary thyroid cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635659

Differential AKT dependency displayed by mouse models of BRAFV600E-initiated melanoma.

30 September 2017

1 reference

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Mutationally activated PIK3CA(H1047R) cooperates with BRAF(V600E) to promote lung cancer progression.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635659

Clinical responses to vemurafenib in patients with metastatic papillary thyroid cancer harboring BRAF(V600E) mutation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635659

Selumetinib-enhanced radioiodine uptake in advanced thyroid cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635659

Relief of feedback inhibition of HER3 transcription by RAF and MEK inhibitors attenuates their antitumor effects in BRAF-mutant thyroid carcinomas.

30 September 2017

1 reference

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A central role for RAF→MEK→ERK signaling in the genesis of pancreatic ductal adenocarcinoma.

30 September 2017

1 reference

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Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR.

30 September 2017

1 reference

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An activating Pik3ca mutation coupled with Pten loss is sufficient to initiate ovarian tumorigenesis in mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635659

Thyrocyte-specific inactivation of p53 and Pten results in anaplastic thyroid carcinomas faithfully recapitulating human tumors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635659

Small-molecule MAPK inhibitors restore radioiodine incorporation in mouse thyroid cancers with conditional BRAF activation

30 September 2017

1 reference

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Improved survival with vemurafenib in melanoma with BRAF V600E mutation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635659

Mutationally activated BRAF(V600E) elicits papillary thyroid cancer in the adult mouse

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635659

4E-BP1 is a key effector of the oncogenic activation of the AKT and ERK signaling pathways that integrates their function in tumors

30 September 2017

1 reference

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Genetic alterations in the phosphatidylinositol-3 kinase/Akt pathway in thyroid cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635659

The discovery of the benzhydroxamate MEK inhibitors CI-1040 and PD 0325901.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635659

The identification of 2-(1H-indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a potent, selective, orally bioavailable inhibitor of class I PI3 kinase for the treatment of cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635659

A new mouse model to explore the initiation, progression, and therapy of BRAFV600E-induced lung tumors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635659

BRAF mutation in thyroid cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635659

Mutations of the BRAF gene in human cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635659

A National Cancer Data Base report on 53,856 cases of thyroid carcinoma treated in the U.S., 1985-1995 [see commetns]

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635659

Anaplastic carcinoma of the thyroid

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635659

Establishment of 2 human thyroid-carcinoma cell-lines (8305c, 8505c) bearing p53 gene-mutations.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635659

Cre/loxP-mediated inactivation of the murine Pten tumor suppressor gene.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635659

Oncogenic mutations of PIK3CA in human cancers

29 June 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24770869

12 December 2020

inferred from PubMed ID database lookup

Universal markers of thyroid malignancies: galectin-3, HBME-1, and cytokeratin-19

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24770869

12 December 2020

inferred from PubMed ID database lookup

Anaplastic thyroid carcinoma: a 50-year experience at a single institution

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24770869

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1158/1541-7786.MCR-14-0158-T

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24770869%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24770869%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24770869%20AND%20SRC:MED&resulttype=core&format=json