Genome-wide analysis of retroviral DNA integration (Q36263002)

13 August 2017

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title

Genome-wide analysis of retroviral DNA integration (English)

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13 August 2017

Jeremy Leipzig

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Christian Hoffmann

object named as

Christian Hoffmann

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Angela Ciuffi

object named as

Angela Ciuffi

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author name string

Frederic Bushman

1

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13 August 2017

Mary Lewinski

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13 August 2017

Stephen Barr

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13 August 2017

Sridhar Hannenhalli

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13 August 2017

language of work or name

English

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publication date

1 November 2005

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Nature Reviews Microbiology

13 August 2017

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13 August 2017

3

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13 August 2017

11

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13 August 2017

848-858

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https://scigraph.springernature.com/pub.10.1038/nrmicro1263

13 August 2017

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cites work

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HIV-1 integration in the human genome favors active genes and local hotspots

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Transcription start regions in the human genome are favored targets for MLV integration

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Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences

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A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency

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LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

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Selective degradation of integrated murine leukemia proviral DNA by deoxyribonucleases

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Highly preferred targets for retrovirus integration

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The avian retroviral IN protein is both necessary and sufficient for integrative recombination in vitro.

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Activities of human immunodeficiency virus (HIV) integration protein in vitro: specific cleavage and integration of HIV DNA

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Nucleosomes, DNA-binding proteins, and DNA sequence modulate retroviral integration target site selection

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Tethering human immunodeficiency virus 1 integrase to a DNA site directs integration to nearby sequences

21 January 2018

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In vitro integration of human immunodeficiency virus type 1 cDNA into targets containing protein-induced bends

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Relationship between retroviral DNA integration and gene expression

21 January 2018

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Simian virus 40 minichromosomes as targets for retroviral integration in vivo

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Human immunodeficiency virus integrase directs integration to sites of severe DNA distortion within the nucleosome core

21 January 2018

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Integration of human immunodeficiency virus DNA: adduct interference analysis of required DNA sites

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Disruption of the terminal base pairs of retroviral DNA during integration

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Initial sequencing and analysis of the human genome

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The human transcriptome map reveals extremes in gene density, intron length, GC content, and repeat pattern for domains of highly and weakly expressed genes

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The DNA sequence and analysis of human chromosome 6

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Genome-wide analysis of chromosomal features repressing human immunodeficiency virus transcription.

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Cellular gene expression upon human immunodeficiency virus type 1 infection of CD4(+)-T-cell lines

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Temporal gene regulation during HIV-1 infection of human CD4+ T cells

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Global analysis of cellular transcription following infection with an hiv-based vector

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Considering nuclear compartmentalization in the light of nuclear dynamics

21 January 2018

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Retroviral vector integration occurs in preferred genomic targets of human bone marrow-repopulating cells

21 January 2018

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Insertion of retroviral vectors in NOD/SCID repopulating human peripheral blood progenitor cells occurs preferentially in the vicinity of transcription start regions and in introns

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What made Hanno Buddenbrook sick?

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Genome-wide analyses of avian sarcoma virus integration sites

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Relationship between retroviral DNA-integration-site selection and host cell transcription

21 January 2018

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Distinct genomic integration of MLV and SIV vectors in primate hematopoietic stem and progenitor cells

21 January 2018

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AAV serotype 2 vectors preferentially integrate into active genes in mice

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Integration by design

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Controlling integration specificity of a yeast retrotransposon

21 January 2018

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Targeting survival: integration site selection by retroviruses and LTR-retrotransposons

21 January 2018

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Role of the non-homologous DNA end joining pathway in the early steps of retroviral infection

21 January 2018

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HIV-1 cDNA integration: requirement of HMG I(Y) protein for function of preintegration complexes in vitro

21 January 2018

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Regulatory mechanisms by which barrier-to-autointegration factor blocks autointegration and stimulates intermolecular integration of Moloney murine leukemia virus preintegration complexes

21 January 2018

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LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes

21 January 2018

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Binding and stimulation of HIV-1 integrase by a human homolog of yeast transcription factor SNF5

21 January 2018

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HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells

21 January 2018

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LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells

21 January 2018

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Human cell proteins and human immunodeficiency virus DNA integration

21 January 2018

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Targeting retroviral integration

21 January 2018

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Targeting of retroviral integrase by fusion to a heterologous DNA binding domain: in vitro activities and incorporation of a fusion protein into viral particles

21 January 2018

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HIV insertions within and proximal to host cell genes are a common finding in tissues containing high levels of HIV DNA and macrophage-associated p24 antigen expression

21 January 2018

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Recovery of replication-competent HIV despite prolonged suppression of plasma viremia

21 January 2018

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Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy

21 January 2018

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Resting CD4+ T cells from human immunodeficiency virus type 1 (HIV-1)-infected individuals carry integrated HIV-1 genomes within actively transcribed host genes

21 January 2018

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The site of HIV-1 integration in the human genome determines basal transcriptional activity and response to Tat transactivation

21 January 2018

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HIV reproducibly establishes a latent infection after acute infection of T cells in vitro.

21 January 2018

1 reference

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Transcriptional interference in avian retroviruses—implications for the promoter insertion model of leukaemogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1263

Transcriptional interference perturbs the binding of Sp1 to the HIV-1 promoter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1263

Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1263

Viral dynamics in human immunodeficiency virus type 1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1263

HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1263

Promoter trapping reveals significant differences in integration site selection between MLV and HIV vectors in primary hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1263

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1263

Genome-wide retroviral insertional tagging of genes involved in cancer in Cdkn2a-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1263

Genome-based identification of cancer genes by proviral tagging in mouse retrovirus-induced T-cell lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1263

A SARCOMA OF THE FOWL TRANSMISSIBLE BY AN AGENT SEPARABLE FROM THE TUMOR CELLS

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1263

Distribution of targets for avian retrovirus DNA integration in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1263

DNA bending creates favored sites for retroviral integration: an explanation for preferred insertion sites in nucleosomes.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1263

Yeast retrotransposons: finding a nice quiet neighborhood

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1263

Integration of murine leukemia virus DNA depends on mitosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1263

The general affinity of lac repressor for E. coli DNA: Implications for gene regulation in procaryotes and eucaryotes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1263

New genes involved in cancer identified by retroviral tagging

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1263

31 March 2020

Identifiers

DOI

10.1038/NRMICRO1263

1 reference

13 August 2017

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