Antimicrobial therapy in critically ill patients: a review of pathophysiological conditions responsible for altered disposition and pharmacokinetic variability (Q36263480)

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English	Antimicrobial therapy in critically ill patients: a review of pathophysiological conditions responsible for altered disposition and pharmacokinetic variability	scientific article

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scholarly article

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

Antimicrobial therapy in critically ill patients: a review of pathophysiological conditions responsible for altered disposition and pharmacokinetic variability (English)

1 reference

Europe PubMed Central

13 August 2017

pathophysiology

1 reference

based on heuristic

inferred from title

pharmacokinetics

1 reference

based on heuristic

inferred from title

Pierluigi Viale

2

object named as

Pierluigi Viale

1 reference

Europe PubMed Central

13 August 2017

3

object named as

Mario Furlanut

1 reference

Europe PubMed Central

13 August 2017

author name string

Federico Pea

1

1 reference

Europe PubMed Central

13 August 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

1 January 2005

1 reference

Europe PubMed Central

13 August 2017

Clinical Pharmacokinetics

1 reference

Europe PubMed Central

13 August 2017

44

1 reference

Europe PubMed Central

13 August 2017

1009-1034

1 reference

Europe PubMed Central

13 August 2017

10

1 reference

Europe PubMed Central

13 August 2017

https://scigraph.springernature.com/pub.10.2165/00003088-200544100-00002

0 references

Effect of once-daily dosing vs. multiple daily dosing of tobramycin on enzyme markers of nephrotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Urinary bactericidal activity, urinary excretion and plasma concentrations of gatifloxacin (400 mg) versus ciprofloxacin (500 mg) in healthy volunteers after a single oral dose

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of amikacin in hematologic malignancies

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low plasma cefepime levels in critically ill septic patients: pharmacokinetic modeling indicates improved troughs with revised dosing

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rational empiric antibiotic prescription in the ICU.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Septic shock: pathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Population pharmacokinetic study of teicoplanin in severely neutropenic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cefepime versus cefpirome: the importance of creatinine clearance

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simplified dosing and monitoring of vancomycin for the burn care clinician

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiovascular and renal hemodynamic effects of intravenous infusions of the selective DA1 agonist, fenoldopam, used alone or in combination with dopamine and dobutamine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The necessity of increased doses of amikacin in burn patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and tissue penetration of ceftazidime: studies on lymph, aqueous humour, skin blister, cerebrospinal and pleural fluid

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of systemically administered antibiotics in patients with thermal injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluctuation of the volume of distribution of amikacin and its effect on once-daily dosage and clearance in a seriously ill patient

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of altered volume of distribution on aminoglycoside levels in patients in surgical intensive care

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of teicoplanin in burn patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of malignancy on the pharmacokinetics of vancomycin in infants and children.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Initial dosage regimens of gentamicin in patients with burns

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

First case of VRSA identified in Michigan.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Therapeutic monitoring of teicoplanin in a severely burned patient]

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pathogenesis of sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered gentamicin distribution in ascitic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nosocomial infections in adult intensive-care units

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of ceftazidime in patients with liver cirrhosis and ascites

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antimicrobial action and pharmacokinetics/pharmacodynamics: the use of AUIC to improve efficacy and avoid resistance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inadequacy of standard aminoglycoside loading doses in acutely ill patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of antibiotics in burn patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Appropriate use of antimicrobial agents: challenges and strategies for improvement

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Teicoplanin in patients with acute leukaemia and febrile neutropenia: a special population benefiting from higher dosages

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The kinetics of cefuroxime in ascitic and pleural fluid

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The evaluation of creatinine clearance in spinal cord injury patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of ceftriaxone in patients with renal and liver insufficiency and correlations with a physiologic nonlinear protein binding model

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolonged low-dose dopamine infusion induces a transient improvement in renal function in hemodynamically stable, critically ill patients: a single-blind, prospective, controlled study

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical pharmacology of the fluoroquinolones: studies in human dynamic/kinetic models

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variation in the pharmacokinetics of gentamicin and tobramycin in patients with pleural effusions and hypoalbuminemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The importance of pharmacokinetic/pharmacodynamic surrogate markers to outcome. Focus on antibacterial agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The prevalence of nosocomial infection in intensive care units in Europe. Results of the European Prevalence of Infection in Intensive Care (EPIC) Study. EPIC International Advisory Committee

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Guidelines on antimicrobial chemotherapy for prevention and treatment of infections in the intensive care unit

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Emerging mechanisms of fluoroquinolone resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacodynamics of intravenous ciprofloxacin in seriously ill patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and pharmacodynamics of fluoroquinolones

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased dosage requirements of gentamicin in burn patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The influence of mini-BAL cultures on patient outcomes: implications for the antibiotic management of ventilator-associated pneumonia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Strategy of antibiotic rotation: long-term effect on incidence and susceptibilities of Gram-negative bacilli responsible for ventilator-associated pneumonia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic study of penetration of meropenem into pleural effusion in patients with pleurisy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of vancomycin therapeutic drug monitoring on patient care

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Surgery and intensive care procedures affect the target site distribution of piperacillin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered aminoglycoside pharmacokinetics in the critically ill

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transiently altered acetaminophen metabolism after liver transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative pharmacokinetics and pharmacodynamics of the newer fluoroquinolone antibacterials

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High vancomycin dosage regimens required by intensive care unit patients cotreated with drugs to improve haemodynamics following cardiac surgical procedures.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antimicrobial cycling: lessons learned from the aminoglycoside experience

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic and pharmacodynamic considerations when treating patients with sepsis and septic shock

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amikacin Bayesian forecasting in critically ill patients with sepsis and cirrhosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacodynamic evaluation of factors associated with the development of bacterial resistance in acutely ill patients during therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic parameters of vancomycin for therapeutic regimens in neutropenic adult patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gentamicin, tobramycin and netilmicin pharmacokinetics in plasma and pleural fluid

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The importance of antibiotic pharmacokinetics in critical illness

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Experience with a once-daily dosing program of aminoglycosides in critically ill patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The post-antibiotic effect

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of ticarcillin/clavulanate in severely burned patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibacterial treatment of invasive mechanical ventilation-associated pneumonia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and pharmacodynamics of fluoroquinolones

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The influence of ascites on the pharmacokinetics of amikacin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modification of empiric antibiotic treatment in patients with pneumonia acquired in the intensive care unit. ICU-Acquired Pneumonia Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of meropenem in febrile neutropenic patients. Swedish study group

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antimicrobial resistance in the intensive care unit: understanding the problem

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical pharmacokinetics in patients with burns

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of ceftazidime in febrile neutropenic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The benefit of appropriate empirical antibiotic treatment in patients with bloodstream infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of antibiotics in burns patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Teicoplanin pharmacokinetics in intravenous drug abusers being treated for bacterial endocarditis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic principles during continuous renal replacement therapy: drugs and dosage

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gentamicin volume of distribution in critically ill septic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between hemodynamic and vital support measures and pharmacokinetic variability of amikacin in critically ill patients with sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Urinary pharmacokinetics and theoretical pharmacodynamics of intravenous levofloxacin in intensive care unit patients treated with 500 mg b.i.d. for ventilator-associated pneumonia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of BAL data on the therapy and outcome of ventilator-associated pneumonia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoalbuminemia as a cause of pleural effusions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered vancomycin dose vs. serum concentration relationship in burn patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Penetration of ceftriaxone into human pleural fluid

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vancomycin Therapy in Patients with Impaired Renal Function: A Nomogram for Dosage

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Restrictive antibiotic policies are appropriate in intensive care units

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic aspects of treating infections in the intensive care unit: focus on drug interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of aztreonam and imipenem in critically ill patients with pneumonia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intrapatient variation of aminoglycoside pharmacokinetics in critically ill surgery patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Factors affecting gentamicin pharmacokinetics in septic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ceftriaxone pharmacokinetics during iatrogenic hydroxyethyl starch-induced hypoalbuminemia: a model to explore the effects of decreased protein binding capacity on highly bound drugs.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Initial aminoglycoside levels in the critically ill

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased aminoglycoside dosage requirements in hematologic malignancy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low cefpirome levels during twice daily dosing in critically ill septic patients: pharmacokinetic modelling calls for more frequent dosing.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of hepatic function on vancomycin pharmacokinetics in patients with cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Penetration of aztreonam into pleural exudate following rapid intravenous bolus or constant infusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacodynamics of levofloxacin: a new paradigm for early clinical trials

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Population pharmacokinetic study of amikacin administered once or twice daily to febrile, severely neutropenic adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of ceftazidime in serum and peritoneal exudate during continuous versus intermittent administration to patients with severe intra-abdominal infections

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic drug monitoring-guided high teicoplanin dosage regimen required to treat a hypoalbuminemic renal transplant patient undergoing continuous venovenous hemofiltration

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of ampicillin in cirrhosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patient survival after human albumin administration. A meta-analysis of randomized, controlled trials

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gentamicin dosage requirements: wide interpatient variations in 242 surgery patients with normal renal function

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of cefoxitin in patients with pleural effusion on a multiple dosage regimen

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systemic vancomycin overexposure in a patient with spinal cord injury who had Staphylococcal sepsis and Clostridium difficile colitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Continuous infusion of beta-lactam antibiotics

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comparative analysis of pharmacokinetics of ceftriaxone in serum and pleural fluid in humans: a study of once daily administration by intramuscular and intravenous routes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic/pharmacodynamic parameters: rationale for antibacterial dosing of mice and men.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of renal blood flow by furosemide

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vancomycin pharmacokinetics in burn patients and intravenous drug abusers

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in vancomycin pharmacokinetics in critically ill infants

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibiotic Levels in Empyemic Pleural Fluid

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered gentamicin pharmacokinetics during the perioperative period

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

De-escalation antimicrobial chemotherapy in critically III patients: pros and cons

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nosocomial infections in the ICU: the growing importance of antibiotic-resistant pathogens

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of tobramycin and gentamicin in abusers of intravenous drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered aminoglycoside pharmacokinetics in critically ill patients with sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacodynamics of fluoroquinolones against Streptococcus pneumoniae in patients with community-acquired respiratory tract infections

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of aztreonam in patients with liver cirrhosis and ascites

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of goal-oriented and model-based clinical pharmacokinetic dosing of aminoglycosides on clinical outcome: a cost-effectiveness analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of antimicrobial drugs in adults before and after removal of a restriction policy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is there a role for antibiotic cycling in the intensive care unit?

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered pharmacokinetics of ceftazidime in critically ill patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of creatinine clearance from serum creatinine

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and bactericidal rates of daptomycin and vancomycin in intravenous drug abusers being treated for gram-positive endocarditis and bacteremia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma and tissue pharmacokinetics of cefpirome in patients with sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapy for ventilator-associated pneumonia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of fluoroquinolones in hepatic failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired target site penetration of beta-lactams may account for therapeutic failure in patients with septic shock

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ceftazidime in acute myeloid leukemia patients with febrile neutropenia: helpfulness of continuous intravenous infusion in maximizing pharmacodynamic exposure

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical pharmacokinetics of piperacillin-tazobactam combination in patients with major burns and signs of infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and tissue concentrations of ceftazidime in burn patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aztreonam pharmacokinetics in burn patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Osmotic diuresis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma, urine and skin pharmacokinetics of cefepime in burns patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potential role of pharmacokinetics, pharmacodynamics, and computerized databases in controlling bacterial resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Programmatic role of the infectious diseases physician in controlling antimicrobial costs in the hospital

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vancomycin-resistant Staphylococcus aureus--Pennsylvania, 2002.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidemiology of drug resistance: implications for a post-antimicrobial era

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of ceftazidime in ascitic fluid

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacodynamic effects of subinhibitory antibiotic concentrations

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intermittent and continuous ceftazidime infusion for critically ill trauma patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ciprofloxacin pharmacokinetics in burn patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is continuous infusion of beta-lactam antibiotics worthwhile?--efficacy and pharmacokinetic considerations

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic dosing of aminoglycosides: a controlled trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical pharmacokinetics of teicoplanin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gentamicin dosing in critically ill patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aminoglycoside pharmacokinetics: dosage requirements and nephrotoxicity in trauma patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antimicrobial management strategies for Gram-positive bacterial resistance in the intensive care unit

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Usefulness of estimating individual pharmacokinetic data for aminoglycoside therapy in seriously ill patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pharmacokinetics of once-daily dosing of ceftriaxone in critically ill patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vancomycin pharmacokinetics and dosage requirements in hematologic malignancies

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vancomycin elimination in patients with burn injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Higher renal replacement therapy dose delivery influences on drug therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of fluid sequestration in the pathogenesis of mediastinitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Issues in pharmacokinetics and pharmacodynamics of anti-infective agents: distribution in tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for antibiotic cycling in control of resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of a 3 mg/kg body weight loading dose of gentamicin or tobramycin in critically ill patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibiotic usage and prescribing policies in the intensive care unit

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Population pharmacokinetics of amikacin in patients with haematological malignancies

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacodynamics and pharmacokinetics of levofloxacin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Penetration of intravenous and oral ciprofloxacin into sterile and empyemic human pleural fluid

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic changes in patients with oedema.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of altered aminoglycoside volume of distribution on the adequacy of a three milligram per kilogram loading dose. Critical Care Research Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacodynamic principles of antimicrobial therapy in the prevention of resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nosocomial pneumonia: the importance of a de-escalating strategy for antibiotic treatment of pneumonia in the ICU.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wide variation in single, daily-dose aminoglycoside pharmacokinetics in patients with burn injuries

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of the renal effects of low to high doses of dopamine and dobutamine in critically ill patients: a single-blind randomized study

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Basic pharmacodynamics of antibacterials with clinical applications to the use of beta-lactams, glycopeptides, and linezolid

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum protein binding and extravascular diffusion of methoxyimino cephalosporins. Time courses of free and total concentrations of cefotaxime and ceftriaxone in serum and pleural exudate

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TDM coupled with Bayesian forecasting should be considered an invaluable tool for optimizing vancomycin daily exposure in unstable critically ill patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and pharmacodynamics of intravenous levofloxacin in patients with early-onset ventilator-associated pneumonia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and ascitic fluid penetration of piperacillin in cirrhosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intravenous azithromycin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variability in aminoglycoside pharmacokinetics in critically ill surgical patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pleural fluid levels of cefoxitin in patients with renal impairment

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Review article: volume expansion in patients with cirrhosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evolution of antibiotic resistance in gram-positive pathogens

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of ascites on tobramycin pharmacokinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative study of penetration of lomefloxacin and ceftriaxone into transudative and exudative pleural effusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of a Meat Meal on Renal Sodium Handling and Sodium Balance

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Levofloxacin disposition in cerebrospinal fluid in patients with external ventriculostomy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of dopamine on renal haemodynamics tubular function and sodium excretion in normal humans.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and drug dosing adjustments during continuous venovenous hemofiltration or hemodiafiltration in critically ill patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological principles of antibiotic prescription in the critically ill.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical pharmacokinetics of ciprofloxacin in patients with major burns

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pharmacokinetics of ceftriaxone and cefotaxime in cirrhotic patients with ascites.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Infection control in the ICU.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Imipenem pharmacokinetics in patients with burns

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Choosing an antibiotic on the basis of pharmacodynamics.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Poststernotomy mediastinitis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Penetration of linezolid into bone, fat, muscle and haematoma of patients undergoing routine hip replacement

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased glomerular filtration rate in patients with major burns and its effect on the pharmacokinetics of tobramycin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Strategies for study of the role of cycling on antimicrobial use and resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The value of an infectious diseases specialist

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of the distribution volume that can be used to calculate the intravenous loading dose

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic profiles of high-dose intravenous ciprofloxacin in severe sepsis. The Baragwanath Ciprofloxacin Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical pharmacokinetics of newer antibacterial agents in liver disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expanded gentamicin volume of distribution in critically ill adult patients receiving total parenteral nutrition

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amikacin pharmacokinetics in plasma and pleural fluid

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of cefepime in patients with thermal burn injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Teicoplanin pharmacokinetics in critically ill paediatric patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A computer-assisted management program for antibiotics and other antiinfective agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of a single dose of teicoplanin in burn patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disposition of cefoxitin in patients with pleural effusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/16176116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2165/00003088-200544100-00002

1 reference

Europe PubMed Central

13 August 2017

Dimensions Publication ID

0 references

1 reference

Europe PubMed Central

13 August 2017

Sitelinks

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