Cholesterol epoxide is a direct-acting mutagen (Q36265172)

13 August 2017

Cholesterol epoxide is a direct-acting mutagen (English)

1 reference

13 August 2017

Sevanian A

1

1 reference

PMCID

345396

13 August 2017

Peterson AR

series ordinal

2

1 reference

PMCID

345396

13 August 2017

language of work or name

English

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publication date

1 July 1984

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13 August 2017

5

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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13 August 2017

81

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13 August 2017

13

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13 August 2017

4198-4202

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The Hela DNA-synthesis inhibition test as a rapid screen for mutagenic carcinogens

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=345396

Carcinogenic effects of steroids

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=345396

Metabolic epidemiology of colon cancer. Fecal bile acids and neutral sterols in colon cancer patients and patients with adenomatous polyps

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=345396

Epoxides as products of lipid autoxidation in rat lungs

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=345396

The metabolic fate of cholesterol-5α,6α-epoxide in vivo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=345396

Mutagenic cholesterol preparations

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=345396

A comparison of the HeLa DNA-synthesis inhibition test and the Ames test for screening of mutagenic carcinogens

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=345396

Steroid epoxides in biologic systems: A review

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=345396

Transformation of hamster embryo cells by neutral sterols and bile acids

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=345396

Cholesterol and cholesterol epoxides in nipple aspirates of human breast fluid

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=345396

Metabolism of cholestane-3 beta,5 alpha,6 beta-triol. II. Identification of two major neutral metabolites in the rat

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=345396

Metabolic fate of epoxycholesterol in the rat.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=345396

Studies on glutathione-S-arene oxidase transferase. A sensitive assay and partial purification of the enzyme from sheep liver.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=345396

A model system for the evaluation of the role of cholesterol -oxide in ultraviolet carcinogenesis.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=345396

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=345396

Oncogenesis, mutagenesis, DNA damage, and cytotoxicity in cultured mammalian cells treated with alkylating agents

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=345396

Chromosome damage and DNA repair induced in human fibroblasts by UV and cholesterol oxide.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=345396

Transformation of hamster embryo cells by cholesterol-α-epoxide and lithocholic acid

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=345396

Effect of cholesterol metabolites and promoting effect of lithocholic acid in colon carcinogenesis in germ-free and conventional F344 rats

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=345396

Isolation and identification of cholesterol α‐oxide and other minor sterols in human serum

29 June 2018

1 reference

12 December 2020

Polarographic determination of the reaction rate of the second step in an SN1 displacement

1 reference

12 December 2020

Formation and metabolism in vitro of 5,6-epoxides of cholesterol and beta-sitosterol

1 reference

12 December 2020

Angiotoxicity of oxygenated sterols and possible precursors

1 reference

12 December 2020

Lipid epoxide hydrolase in rat lung preparations

1 reference

12 December 2020

Cholesterol alpha- and beta-epoxides as obligatory intermediates in the hepatic microsomal metabolism of cholesterol to cholestanetriol

1 reference

12 December 2020

Analysis and physiologic significance of cholesterol epoxide in animal tissues

1 reference

12 December 2020

DNA synthesis, mutagenesis, DNA damage, and cytotoxicity in cultured mammalian cells treated with alkylating agents

1 reference

12 December 2020

Sterol metabolism in the rat. Effect of cholesterol and cholesterol-alpha-epoxide on sterol metabolism in rats fed liquid diets

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.81.13.4198

1 reference

13 August 2017

0 references

1 reference

13 August 2017

1 reference

PMCID

345396