Exploring simvastatin, an antihyperlipidemic drug, as a potential topical antibacterial agent (Q36265781)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26553420%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

Exploring simvastatin, an antihyperlipidemic drug, as a potential topical antibacterial agent (English)

1 reference

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29 February 2020

1 reference

2

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29 February 2020

Mostafa F N Abushahba

3

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29 February 2020

Mohamed N. Seleem

8

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29 February 2020

author name string

Shankar Thangamani

1

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29 February 2020

Maha I Hamed

4

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29 February 2020

Tiago J P Sobreira

5

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29 February 2020

Victoria E Hedrick

6

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29 February 2020

Lake N Paul

7

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29 February 2020

language of work or name

English

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publication date

10 November 2015

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29 February 2020

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29 February 2020

volume

5

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29 February 2020

page(s)

16407

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Creative Commons Attribution 4.0 International

29 February 2020

copyright license

start time

10 November 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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Clp chaperones and proteases are central in stress survival, virulence and antibiotic resistance of Staphylococcus aureus

30 September 2017

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Cell targeting by the Staphylococcus aureus pore-forming toxins: it's not just about lipids

30 September 2017

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Simvastatin enhances protection against Listeria monocytogenes infection in mice by counteracting Listeria-induced phagosomal escape

30 September 2017

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The FDA reboot of antibiotic development

30 September 2017

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Local inflammation exacerbates the severity of Staphylococcus aureus skin infection

30 September 2017

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Silver enhances antibiotic activity against gram-negative bacteria

30 September 2017

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Host gene expression profiling and in vivo cytokine studies to characterize the role of linezolid and vancomycin in methicillin-resistant Staphylococcus aureus (MRSA) murine sepsis model

30 September 2017

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Clinical relevance of the ESKAPE pathogens

30 September 2017

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Adenylate kinase release as a high-throughput-screening-compatible reporter of bacterial lysis for identification of antibacterial agents

30 September 2017

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Potential role of statins on wound healing: review of the literature.

30 September 2017

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Studies on the antibacterial effects of statins--in vitro and in vivo

30 September 2017

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Synergistic combination of chitosan acetate with nanoparticle silver as a topical antimicrobial: efficacy against bacterial burn infections

30 September 2017

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Statin treatment and mortality in bacterial infections--a systematic review and meta-analysis

30 September 2017

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The effect of statins on mortality from severe infections and sepsis: a systematic review and meta-analysis

30 September 2017

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Molecular epidemiology of community-associated meticillin-resistant Staphylococcus aureus in Europe

30 September 2017

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Senescence of staphylococci: using functional genomics to unravel the roles of ClpC ATPase during late stationary phase

30 September 2017

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Targeting low HDL-cholesterol to decrease residual cardiovascular risk in the managed care setting.

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Intermediate vancomycin susceptibility in a community-associated MRSA clone

30 September 2017

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Concomitant reduction of low-density lipoprotein-cholesterol and biomarkers of inflammation with low-dose simvastatin therapy in patients with type 1 diabetes

30 September 2017

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Inhibition of mammalian mitochondrial protein synthesis by oxazolidinones

30 September 2017

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Pharmacokinetic and pharmacodynamic alterations of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors: drug-drug interactions and interindividual differences in transporter and metabolic enzyme functions

30 September 2017

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Recognition of Staphylococcus aureus by the innate immune system

30 September 2017

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Pleiotropic effects of statins

30 September 2017

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Proteomic approach to understanding antibiotic action

30 September 2017

1 reference

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Sublethal concentrations of pleurocidin-derived antimicrobial peptides inhibit macromolecular synthesis in Escherichia coli

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4639749

Preclinical and clinical pharmacology of Rosuvastatin, a new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4639749

Essentiality, expression, and characterization of the class II 3-hydroxy-3-methylglutaryl coenzyme A reductase of Staphylococcus aureus

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4639749

Effect of antibiotics on toxin production and viability of Clostridium perfringens

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4639749

Proteomic signature of fatty acid biosynthesis inhibition available for in vivo mechanism-of-action studies.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4639749

Elevated Linezolid Resistance in Clinical cfr -Positive Staphylococcus aureus Isolates Is Associated with Co-Occurring Mutations in Ribosomal Protein L3

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4639749

Proteomic analysis of the mode of antibacterial action of silver nanoparticles.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4639749

Pharmacodynamics and pharmacokinetics of the HMG-CoA reductase inhibitors. Similarities and differences

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4639749

Simvastatin inhibits planktonic cells and biofilms of Candida and Cryptococcus species.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4639749

Simvastatin improves incisional wound healing in a rat model: an experimental study.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4639749

Statin therapy reduces the mycobacterium tuberculosis burden in human macrophages and in mice by enhancing autophagy and phagosome maturation.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4639749

Simvastatin inhibits Candida albicans biofilm in vitro

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4639749

Unexpected antimicrobial effect of statins

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4639749

Statins as potent antiinflammatory drugs

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4639749

Postoperative intraperitoneal 5-fluoro-2'-deoxyuridine added to chemoradiation in patients curatively resected (R0) for locally advanced gastric and gastroesophageal junction adenocarcinoma

22 September 2018

1 reference

12 December 2020

Lactoferricin B inhibits bacterial macromolecular synthesis in and

1 reference

12 December 2020

Chloramphenicol induced reversible bone marrow suppression. A case report

1 reference

12 December 2020

Etanercept decreases tumor necrosis factor-alpha activity in chronic wound fluid

1 reference

12 December 2020

Impact of antibiotics on expression of virulence-associated exotoxin genes in methicillin-sensitive and methicillin-resistant Staphylococcus aureus

1 reference

12 December 2020

Identifiers

DOI

10.1038/SREP16407

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26553420%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26553420%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

PubMed publication ID

26553420

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26553420%20AND%20SRC:MED&resulttype=core&format=json