Mechanism of action of the arylomycin antibiotics and effects of signal peptidase I inhibition (Q36276904)

13 August 2017

Mechanism of action of the arylomycin antibiotics and effects of signal peptidase I inhibition (English)

1 reference

13 August 2017

Peter A Smith

1

1 reference

13 August 2017

Floyd E Romesberg

series ordinal

2

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13 August 2017

language of work or name

English

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publication date

16 July 2012

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13 August 2017

7

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Antimicrobial Agents and Chemotherapy

inferred from page(s)

published in

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13 August 2017

56

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13 August 2017

10

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13 August 2017

5054-5060

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Type I signal peptidase and protein secretion in Staphylococcus aureus

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457390

Bacterial type I signal peptidases as antibiotic targets

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457390

Synthesis and Characterization of the Arylomycin Lipoglycopeptide Antibiotics and the Crystallographic Analysis of Their Complex with Signal Peptidase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457390

Initial efforts toward the optimization of arylomycins for antibiotic activity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457390

Synthesis and biological characterization of arylomycin B antibiotics

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457390

In vitro activities of arylomycin natural-product antibiotics against Staphylococcus epidermidis and other coagulase-negative staphylococci

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457390

Transport and proofreading of proteins by the twin-arginine translocation (Tat) system in bacteria

30 September 2017

1 reference

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Broad-spectrum antibiotic activity of the arylomycin natural products is masked by natural target mutations

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457390

30 September 2017

1 reference

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Nonoptimal microbial response to antibiotics underlies suppressive drug interactions

30 September 2017

1 reference

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Effects of antibiotics and a proto-oncogene homolog on destruction of protein translocator SecY.

30 September 2017

1 reference

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Bioinformatic comparison of bacterial secretomes

30 September 2017

1 reference

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Solution structure of the parvulin-type PPIase domain of Staphylococcus aureus PrsA – Implications for the catalytic mechanism of parvulins

30 September 2017

1 reference

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Mistranslation of membrane proteins and two-component system activation trigger antibiotic-mediated cell death.

30 September 2017

1 reference

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Protein translocation across the bacterial cytoplasmic membrane.

30 September 2017

1 reference

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Role of group A Streptococcus HtrA in the maturation of SpeB protease

30 September 2017

1 reference

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Structural and initial biological analysis of synthetic arylomycin A2.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457390

Interactions that drive Sec-dependent bacterial protein transport

30 September 2017

1 reference

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Multi-targeting by monotherapeutic antibacterials.

30 September 2017

1 reference

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Mapping the pathways to staphylococcal pathogenesis by comparative secretomics

30 September 2017

1 reference

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The world of subinhibitory antibiotic concentrations

30 September 2017

1 reference

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Mode of action of the new antibiotic for Gram-positive pathogens daptomycin: comparison with cationic antimicrobial peptides and lipopeptides.

30 September 2017

1 reference

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Sortases and the art of anchoring proteins to the envelopes of gram-positive bacteria

30 September 2017

1 reference

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Bad bugs need drugs: an update on the development pipeline from the Antimicrobial Availability Task Force of the Infectious Diseases Society of America

30 September 2017

1 reference

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Inhibition of mutation and combating the evolution of antibiotic resistance

30 September 2017

1 reference

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Molecular insights into aminoglycoside action and resistance

30 September 2017

1 reference

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Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen

30 September 2017

1 reference

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Post-translocational folding of secretory proteins in Gram-positive bacteria

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457390

Role for serine protease HtrA (DegP) of Streptococcus pyogenes in the biogenesis of virulence factors SpeB and the hemolysin streptolysin S.

30 September 2017

1 reference

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Quinolone Resistance Due to Reduced Target Enzyme Expression

30 September 2017

1 reference

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Antagonists of Nucleic Acid Derivatives Viii. Synergism in Combinations of Biochemically Related Antimetabolites

30 September 2017

1 reference

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HtrA is a key factor in the response to specific stress conditions in Lactococcus lactis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457390

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457390

The structure and mechanism of bacterial type I signal peptidases. A novel antibiotic target

30 September 2017

1 reference

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One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products

30 September 2017

1 reference

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Reproducibility of the microdilution checkerboard method for antibiotic synergy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457390

HtrA is essential for efficient secretion of recombinant proteins by Lactococcus lactis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457390

Antagonism of chemical genetic interaction networks resensitize MRSA to β-lactam antibiotics.

30 September 2017

1 reference

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Chemical Probes of Escherichia coli Uncovered through Chemical-Chemical Interaction Profiling with Compounds of Known Biological Activity

22 September 2018

1 reference

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Penicillin-binding protein folding is dependent on the PrsA peptidyl-prolyl cis-trans isomerase in Bacillus subtilis

22 September 2018

1 reference

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Proteolytic processing of Escherichia coli twin-arginine signal peptides by LepB.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457390

Functional classification of drugs by properties of their pairwise interactions.

22 September 2018

1 reference

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The general secretory pathway: a general misnomer?

22 September 2018

1 reference

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Novel lipoglycopeptides as inhibitors of bacterial signal peptidase I.

22 September 2018

1 reference

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Crystallographic and biophysical analysis of a bacterial signal peptidase in complex with a lipopeptide-based inhibitor

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457390

Arylomycins A and B, new biaryl-bridged lipopeptide antibiotics produced by Streptomyces sp. Tü 6075. I. Taxonomy, fermentation, isolation and biological activities.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457390

HtrA is the unique surface housekeeping protease in Lactococcus lactis and is required for natural protein processing

22 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22802255

12 December 2020

inferred from PubMed ID database lookup

PCR-mediated gene replacement in Escherichia coli

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22802255

12 December 2020

inferred from PubMed ID database lookup

The fractional inhibitory concentration (FIC) index as a measure of synergy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22802255

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1128/AAC.00785-12

1 reference

13 August 2017

1 reference

13 August 2017

PubMed publication ID

22802255

1 reference