NAD(P)H:quinone oxidoreductase 1 reduces the mutagenicity of DNA caused by NADPH:P450 reductase-activated metabolites of benzo(a)pyrene quinones (Q36291825)

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English	NAD(P)H:quinone oxidoreductase 1 reduces the mutagenicity of DNA caused by NADPH:P450 reductase-activated metabolites of benzo(a)pyrene quinones	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

13 August 2017

NAD(P)H:quinone oxidoreductase 1 reduces the mutagenicity of DNA caused by NADPH:P450 reductase-activated metabolites of benzo(a)pyrene quinones (English)

1 reference

Europe PubMed Central

13 August 2017

author name string

P Joseph

1

1 reference

Europe PubMed Central

13 August 2017

A K Jaiswal

2

1 reference

Europe PubMed Central

13 August 2017

language of work or name

0 references

publication date

1 March 1998

1 reference

Europe PubMed Central

13 August 2017

British Journal of Cancer

1 reference

Europe PubMed Central

13 August 2017

77

1 reference

Europe PubMed Central

13 August 2017

5

1 reference

Europe PubMed Central

13 August 2017

709-719

1 reference

Europe PubMed Central

13 August 2017

https://scigraph.springernature.com/pub.10.1038/bjc.1998.117

0 references

Benzo[a]pyrene-induced murine skin tumors exhibit frequent and characteristic G to T mutations in the p53 gene

1 reference

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The electrophile counterattack response: protection against neoplasia and toxicity.

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Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates

1 reference

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30 September 2017

NAD(P)H:quinone oxidoreductase1 (DT diaphorase) specifically prevents the formation of benzo[a]pyrene quinone-DNA adducts generated by cytochrome P4501A1 and P450 reductase

1 reference

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30 September 2017

Covalent binding of benzo[a]pyrene 7,8-dihydrodiol 9,10-epoxides to DNA: molecular structures, induced mutations and biological consequences

1 reference

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30 September 2017

Enzyme-directed bioreductive drug development revisited: a commentary on recent progress and future prospects with emphasis on quinone anticancer agents and quinone metabolizing enzymes, particularly DT-diaphorase.

1 reference

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30 September 2017

Benzo[alpha]pyrene metabolism, activation and carcinogenesis: role and regulation of mixed-function oxidases and related enzymes

1 reference

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30 September 2017

Mutagenicity of quinones: pathways of metabolic activation and detoxification

1 reference

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Identification of a common chemical signal regulating the induction of enzymes that protect against chemical carcinogenesis

1 reference

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Oncogene activation in chemical carcinogenesis

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Human dioxin-inducible cytosolic NAD(P)H:menadione oxidoreductase. cDNA sequence and localization of gene to chromosome 16

1 reference

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Molecular mechanisms of quinone cytotoxicity

1 reference

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p53 mutations in human cancers

1 reference

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1 reference

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30 September 2017

Quinone chemistry and toxicity

1 reference

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Rapid detection of inducers of enzymes that protect against carcinogens

1 reference

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Metabolic activation of carcinogens

1 reference

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An Escherichia coli plasmid-based, mutational system in which supF mutants are selectable: insertion elements dominate the spontaneous spectra

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NAD(P)H:quinone oxidoreductase1 (DT-diaphorase): expression, regulation, and role in cancer.

1 reference

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Formation of benzo[a]pyrene-3,6-quinol mono- and diglucuronides in rat liver microsomes.

1 reference

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Human NADPH-P450 oxidoreductase: complementary DNA cloning, sequence and vaccinia virus-mediated expression and localization of the CYPOR gene to chromosome 7.

1 reference

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29 June 2018

The human dioxin-inducible NAD(P)H: quinone oxidoreductase cDNA-encoded protein expressed in COS-1 cells is identical to diaphorase 4.

1 reference

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Mutational specificity of the (+)-anti-diol epoxide of benzo[a]pyrene in a supF gene of an Escherichia coli plasmid: DNA sequence context influences hotspots, mutagenic specificity and the extent of SOS enhancement of mutagenesis.

1 reference

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1 reference

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Mutagenicity and cytotoxicity of naphthoquinones for Ames Salmonella tester strains.

1 reference

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Mutagenicity of benzoquinones for Ames Salmonella tester strains.

1 reference

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The determination of lactic dehydrogenase with a tetrazolium salt

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DT-diaphorase as a quinone reductase: a cellular control device against semiquinone and superoxide radical formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9514048

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/BJC.1998.117

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

ResearchGate publication ID

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