Isoxyl activation is required for bacteriostatic activity against Mycobacterium tuberculosis (Q36295362)

13 August 2017

Isoxyl activation is required for bacteriostatic activity against Mycobacterium tuberculosis (English)

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Mycobacterium tuberculosis

13 August 2017

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8

Brigitte Gicquel

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Yves L Janin

object named as

Yves L Janin

2

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Mary Jackson

object named as

Mary Jackson

9

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Nathalie Barilone

4

object named as

Nathalie Barilone

1 reference

13 August 2017

Jana Korduláková

1

1 reference

13 August 2017

Avraham Liav

3

1 reference

13 August 2017

Tiago Dos Vultos

5

1 reference

13 August 2017

Jean Rauzier

6

1 reference

13 August 2017

Patrick J Brennan

7

1 reference

13 August 2017

language of work or name

English

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publication date

4 September 2007

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13 August 2017

6

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Antimicrobial Agents and Chemotherapy

inferred from page(s)

published in

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13 August 2017

51

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13 August 2017

3824-3829

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13 August 2017

11

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EthA, a common activator of thiocarbamide-containing drugs acting on different mycobacterial targets

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151411

Emergence of Mycobacterium tuberculosis with extensive resistance to second-line drugs--worldwide, 2000-2004.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151411

Oxidative activation of thiacetazone by the Mycobacterium tuberculosis flavin monooxygenase EtaA and human FMO1 and FMO3.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151411

The Prodrug Activator EtaA from Mycobacterium tuberculosis Is a Baeyer-Villiger Monooxygenase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151411

Resazurin microtiter assay plate testing of Mycobacterium tuberculosis susceptibilities to second-line drugs: rapid, simple, and inexpensive method

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151411

Unique mechanism of action of the thiourea drug isoxyl on Mycobacterium tuberculosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151411

Definition of the first mannosylation step in phosphatidylinositol mannoside synthesis. PimA is essential for growth of mycobacteria

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151411

The antituberculosis drug ethionamide is activated by a flavoprotein monooxygenase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151411

Tuberculosis. Scientific blueprint for tuberculosis drug development

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151411

Ethionamide activation and sensitivity in multidrug-resistant Mycobacterium tuberculosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151411

Activation of the pro-drug ethionamide is regulated in mycobacteria

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151411

Antimycobacterial activities of isoxyl and new derivatives through the inhibition of mycolic acid synthesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151411

Pharmacology and Toxicology of Isoxyl

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151411

Structural studies and synthetic applications of Baeyer-Villiger monooxygenases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151411

Clinical Experience with Thiocarlide (Isoxyl)

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151411

Effects of Ethionamide and Isoxyl on Mycolic Acid Synthesis in Mycobacterium tuberculosis bcg

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151411

Selective intracellular accumulation of the major metabolite issued from the activation of the prodrug ethionamide in mycobacteria

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151411

Identification of Nudix hydrolase family members with an antimutator role in Mycobacterium tuberculosis and Mycobacterium smegmatis.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151411

Global surveillance for antituberculosis-drug resistance, 1994-1997. World Health Organization-International Union against Tuberculosis and Lung Disease Working Group on Anti-Tuberculosis Drug Resistance Surveillance.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151411

Identification of a Baeyer-Villiger monooxygenase sequence motif

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151411

Symmetrical and unsymmetrical analogues of isoxyl; active agents against Mycobacterium tuberculosis

21 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2151411

Sequences in dendrons and dendrimers

5 December 2018

1 reference

12 December 2020

[Monotherapy with isoxyl-DAT in cases of tuberculosis under hospital care]

1 reference

12 December 2020

A clinical trial of thiocarlide (4-4′ diisoamyloxythiocarbanilide)

1 reference

12 December 2020

An inducible expression system permitting the efficient purification of a recombinant antigen from Mycobacterium smegmatis

1 reference

12 December 2020

Identifiers

DOI

10.1128/AAC.00433-07

1 reference

13 August 2017

1 reference

13 August 2017

1 reference