Arylamine N-acetyltransferases: what we learn from genes and genomes (Q36300809)

13 August 2017

1 reference

title

Arylamine N-acetyltransferases: what we learn from genes and genomes (English)

1 reference

13 August 2017

Sotiria Boukouvala

1

1 reference

PubMed ID

16257833

13 August 2017

Giannoulis Fakis

series ordinal

2

1 reference

PubMed ID

16257833

13 August 2017

language of work or name

English

0 references

publication date

1 January 2005

1 reference

13 August 2017

Drug Metabolism Reviews

1 reference

13 August 2017

37

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13 August 2017

3

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13 August 2017

511-564

1 reference

An arylamine acetyltransferase (AT-I) from Syrian golden hamster liver: cloning, complete nucleotide sequence, and expression in mammalian cells

13 August 2017

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Expression in human prostate of drug- and carcinogen-metabolizing enzymes: association with prostate cancer risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Redox regulation of the human xenobiotic metabolizing enzyme arylamine N-acetyltransferase 1 (NAT1). Reversible inactivation by hydrogen peroxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Arylamine N-acetyltransferase 2 slow acetylator polymorphisms in unrelated Iranian individuals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Investigation of interaction between N-acetyltransferase 2 and heterocyclic amines as potential risk factors for colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Arylamine N-acetyltransferase is required for synthesis of mycolic acids and complex lipids in Mycobacterium bovis BCG and represents a novel drug target

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Nucleotide sequence of a full-length cDNA for arylamine N-acetyltransferase from rabbit liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

N-acetylation pharmacogenetics: a gene deletion causes absence of arylamine N-acetyltransferase in liver of slow acetylator rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Human arylamine N-acetyltransferase genes: isolation, chromosomal localization, and functional expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Molecular mechanism of slow acetylation of drugs and carcinogens in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Structural analysis of the genes for human arylamine N-acetyltransferases and characterisation of alternative transcripts

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Identification and functional characterization of novel polymorphisms associated with the genes for arylamine N-acetyltransferases in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Structure and transcriptional regulation of the Nat2 gene encoding for the drug-metabolizing enzyme arylamine N-acetyltransferase type 2 in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

N-Acetyltransferase 2 Acetylation Polymorphism: Prevalence of Slow Acetylators Does Not Differ between Atopic Dermatitis Patients and Healthy Subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Synthesis and in vitro evaluation of novel small molecule inhibitors of bacterial arylamine N-acetyltransferases (NATs).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

An approach to identifying novel substrates of bacterial arylamine N-acetyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Correlation between genotype and phenotype of the human arylamine N-acetyltransferase type 1 (NAT1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Pharmacogenetics of the arylamine N-acetyltransferases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Identification of a minimal promoter sequence for the human N-acetyltransferase Type I gene that binds AP-1 (activator protein 1) and YY-1 (Yin and Yang 1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Genomic organization of human arylamine N-acetyltransferase Type I reveals alternative promoters that generate different 5'-UTR splice variants with altered translational activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Proteasomal degradation of N-acetyltransferase 1 is prevented by acetylation of the active site cysteine: a mechanism for the slow acetylator phenotype and substrate-dependent down-regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Only low levels of exogenous N-acetyltransferase can be achieved in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Role of N-acetyltransferase phenotypes in bladder carcinogenesis: a pharmacogenetic epidemiological approach to bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Preliminary phenotypic map of chromosome 4p16 based on 4p deletions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Functional identification of LZTS1 as a candidate prostate tumor suppressor gene on human chromosome 8p22.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Strong association between N-acetyltransferase 2 genotype and PD in Hong Kong Chinese

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Comparison of murine Supt4h and a nearly identical expressed, processed gene: evidence of sequence conservation through gene conversion extending into the untranslated regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Purification and characterization of an arylamine N-acetyltransferase from the bacteria Aeromonas hydrophilia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Generation and analysis of mice with a targeted disruption of the arylamine N-acetyltransferase type 2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Biology and function of the reversible sulfation pathway catalysed by human sulfotransferases and sulfatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Analysis of candidate modifier loci for the severity of colonic familial adenomatous polyposis, with evidence for the importance of the N-acetyl transferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Reversible inhibition of the human xenobiotic-metabolizing enzyme arylamine N-acetyltransferase 1 by S-nitrosothiols

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Histological localization of acetyltransferases in human tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

NMR investigation of the catalytic mechanism of arylamine N-acetyltransferase from Salmonella typhimurium

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Identification and functional characterization of arylamine N-acetyltransferases in eubacteria: evidence for highly selective acetylation of 5-aminosalicylic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Determination of human NAT2 acetylator genotype by restriction fragment-length polymorphism and allele-specific amplification

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Identification of a novel allele at the human NAT1 acetyltransferase locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Structure and restriction fragment length polymorphism of genes for human liver arylamine N-acetyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Complementary DNAs for two arylamine N-acetyltransferases with identical 5' non-coding regions from rat pineal gland

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Alternative poly(A) site selection in complex transcription units: means to an end?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Chromosome mapping of the genes for murine arylamine N-acetyltransferases (NATs), enzymes involved in the metabolism of carcinogens: identification of a novel upstream noncoding exon for murine Nat2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Genotypes of N-acetyltransferase-2 and risk of bladder cancer: a case-control study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Lessons from the rifamycin biosynthetic gene cluster

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Isolation and mapping of a cosmid clone containing the human NAT2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Functional characterization of human N-acetyltransferase 2 (NAT2) single nucleotide polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Polymorphisms of drug-metabolizing enzymes CYP2C9, CYP2C19, CYP2D6, CYP1A1, NAT2 and of P-glycoprotein in a Russian population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

N-acetyl transferase 2 genotypes, meat intake and breast cancer risk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

The enhanced bladder cancer susceptibility of NAT2 slow acetylators towards aromatic amines: a review considering ethnic differences

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Understanding the role of xenobiotic-metabolism in chemical carcinogenesis using gene knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Genetic polymorphism of N-acetyltransferase-2, glutathione S-transferase-M1, and cytochromes P450IIE1 and P450IID6 in the susceptibility to head and neck cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

N-acetyltransferase 2 and bladder cancer: an overview and consideration of the evidence for gene-environment interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Mass spectrometric investigation of the mechanism of inactivation of hamster arylamine N-acetyltransferase 1 by N-hydroxy-2-acetylaminofluorene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Genetic polymorphisms of drug-metabolizing enzymes and susceptibility to oral cavity cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

N-acetyltransferase-2 gene polymorphism as a possible biomarker for prostate cancer in Japanese men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Genotype and allele frequencies of TPMT, NAT2, GST, SULT1A1 and MDR-1 in the Egyptian population

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

N-acetyltransferase-2 polymorphism in Parkinson's disease: the Rotterdam study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Germline sequence variants of the LZTS1 gene are associated with prostate cancer risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

N-acetylation phenotype and genotype and risk of bladder cancer in benzidine-exposed workers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Multiple N-acetyltransferases and drug metabolism. Tissue distribution, characterization and significance of mammalian N-acetyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Molecular genetics and function of NAT1 and NAT2: role in aromatic amine metabolism and carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Molecular genetics of human polymorphic N-acetyltransferase: enzymatic analysis of 15 recombinant wild-type, mutant, and chimeric NAT2 allozymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Update on consensus arylamine N-acetyltransferase gene nomenclature.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Chromosomal localization of human genes for arylamine N-acetyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Expression of arylamine N-acetyltransferase in human intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

GSTM1 and NAT2 polymorphisms in operable and non-operable lung cancer patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

The effect of vitamin C on N-acetyltransferase activity in Klebsiella pneumoniae

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Genetic polymorphisms of N-acetyltransferase 1 and 2 and risk of cigarette smoking-related bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Polymorphism of the N-acetyltransferase 2 gene, red meat intake, and the susceptibility of hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

N-acetyltransferase 2 genotype in colorectal cancer and selective gene retention in cancers with chromosome 8p deletions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

N-acetyl transferase 1: two polymorphisms in coding sequence identified in colorectal cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

GST, NAT, SULT1A1, CYP1B1 genetic polymorphisms, interactions with environmental exposures and bladder cancer risk in a high-risk population

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Identification of the major promoter and non-coding exons of the human arylamine N-acetyltransferase 1 gene (NAT1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Initial sequencing and analysis of the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

FEZ1/LZTS1 gene at 8p22 suppresses cancer cell growth and regulates mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Partial purification and properties of the isoniazid transacetylase in human liver. Its relationship to the acetylation of p-aminosalicylic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

NAT gene polymorphisms and susceptibility to Alzheimer's disease: identification of a novel NAT1 allelic variant

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Analysis of six SNPs of NAT2 in Ngawbe and Embera Amerindians of Panama and determination of the Embera acetylation phenotype using caffeine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Structural investigation of mutant Mycobacterium smegmatis arylamine N-acetyltransferase: a model for a naturally occurring functional polymorphism in Mycobacterium tuberculosis arylamine N-acetyltransferase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Allelic polymorphism of GSTM1 and NAT2 genes modifies dietary-induced DNA damage in colorectal mucosa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Expression of N-acetyltransferase (NAT) in cultured human uroepithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

N-acetyltransferase (NAT2) polymorphism and breast cancer susceptibility: a lack of association in a case-control study of Turkish population

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Genetic susceptibility to breast cancer in French-Canadians: role of carcinogen-metabolizing enzymes and gene-environment interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Maternal smoking and the risk of orofacial clefts: Susceptibility with NAT1 and NAT2 polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Biochemical and genetic analysis of two acetyltransferases from hamster tissues that can metabolize aromatic amine derivatives.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

N-acetyltransferase (NAT1, NAT2) and glutathione S-transferase (GSTM1, GSTT1) polymorphisms in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Novel human N-acetyltransferase 2 alleles that differ in mechanism for slow acetylator phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

2-Aminofluorene-DNA adducts in mouse urinary bladder: effect of age, sex and acetylator phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

2-Aminofluorene metabolism and DNA adduct formation by mononuclear leukocytes from rapid and slow acetylator mouse strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Molecular analysis of the N-acetyltransferase 1 gene (NAT1*) using polymerase chain reaction-restriction fragment-single strand conformation polymorphism assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Characterisation of xenobiotic-metabolising enzyme expression in human bronchial mucosa and peripheral lung tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

GSTT1 null genotype increases risk of premenopausal breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Prenatal expression of N-acetyltransferases in C57Bl/6 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Acetylation of p-aminobenzoylglutamate, a folic acid catabolite, by recombinant human arylamine N-acetyltransferase and U937 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Role of acetylation in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Xenobiotic inducible regions of the human arylamine N-acetyltransferase 1 and 2 genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Genetic variation and exposure related risk estimation: will toxicology enter a new era? DNA repair and cancer as a paradigm

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Initial sequencing and comparative analysis of the mouse genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

The human CC chemokine receptor 5 (CCR5) gene. Multiple transcripts with 5'-end heterogeneity, dual promoter usage, and evidence for polymorphisms within the regulatory regions and noncoding exons

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

The COOH terminus of arylamine N-acetyltransferase from Salmonella typhimurium controls enzymic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Association between the N-acetylation genetic polymorphism and bronchial asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Carcinogenic factors in food with relevance to colon cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Two arylamine N-acetyltransferases from chicken pineal gland as identified by cDNA cloning

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Heterologous introns can enhance expression of transgenes in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Eubacterial arylamine N-acetyltransferases - identification and comparison of 18 members of the protein family with conserved active site cysteine, histidine and aspartate residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Molecular portraits of human breast tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Expression and purification of the rifamycin amide synthase, RifF, an enzyme homologous to the prokaryotic arylamine N-acetyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Lack of association between the polyadenylation polymorphism in the NAT1 (acetyltransferase 1) gene and colorectal adenomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Characterization of C14orf4, a novel intronless human gene containing a polyglutamine repeat, mapped to the ARVD1 critical region

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Genome sequence of the Brown Norway rat yields insights into mammalian evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Slow N-acetylation genotype is a susceptibility factor in occupational and smoking related bladder cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

3D model of human arylamine N-acetyltransferase 2: structural basis of the slow acetylator phenotype of the R64Q variant and analysis of the active-site loop.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

In silico sequence analysis of arylamine N-acetyltransferases: evidence for an absence of lateral gene transfer from bacteria to vertebrates and first description of paralogs in bacteria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Skeletal Muscles Express the Xenobiotic-metabolizing Enzyme ArylamineN-acetyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Back to the roots of a new exon--the molecular archaeology of a SP100 splice variant

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

The impact of interindividual variation in NAT2 activity on benzidine urinary metabolites and urothelial DNA adducts in exposed workers

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Metabolic activation of mutagenic N-hydroxyarylamines by O-acetyltransferase in Salmonella typhimurium TA98.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Microbial genes in the human genome: lateral transfer or gene loss?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

The structure of arylamine N-acetyltransferase from Mycobacterium smegmatis--an enzyme which inactivates the anti-tubercular drug, isoniazid

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Binding of the anti-tubercular drug isoniazid to the arylamine N-acetyltransferase protein from Mycobacterium smegmatis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Identification of single-nucleotide polymorphisms (SNPs) of human N-acetyltransferase genes NAT1, NAT2, AANAT, ARD1 and L1CAM in the Japanese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Novel allele containing a 190C>T nonsynonymous substitution in the N-acetyltransferase (NAT2) gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Polymorphism in human N-acetyltransferase--the case of the missing allele

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Xenogenetics in multifactorial disease susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Arylamine N-acetyltransferases: a pharmacogenomic approach to drug metabolism and endogenous function

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Structure of arylamine N-acetyltransferase reveals a catalytic triad

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

GSTM-1 and NAT2 and genetic alterations in colon tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Expression of arylamine N-acetyltransferases in pre-term placentas and in human pre-implantation embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Alternative splicing in the control of gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

A simplified assay for the arylamine N-acetyltransferase 2 polymorphism validated by phenotyping with isoniazid

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

mRNA translation: influence of the 5' and 3' untranslated regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

The genomic structure of human olfactory receptor genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Arylamine N-acetyltransferase type 2 (NAT2), chromosome 8 aneuploidy, and identification of a novel NAT1 cosmid clone: an investigation in bladder cancer by interphase FISH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Immunochemical detection of arylamine N-acetyltransferase in normal and neoplastic bladder

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Immunochemical detection of arylamine N-acetyltransferase during mouse embryonic development and in adult mouse brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Generation and functional characterization of arylamine N-acetyltransferase Nat1/Nat2 double-knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Human acetyl CoA:arylamine N-acetyltransferase variants generated by random mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Meat consumption, cigarette smoking, and genetic susceptibility in the etiology of colorectal cancer: results from a Dutch prospective study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Cytochrome P450 (CYP) 1A2, sulfotransferase (SULT) 1A1, and N-acetyltransferase (NAT) 2 polymorphisms and susceptibility to urothelial cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Arylamine N-acetyltransferases - of mice, men and microorganisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Arylamine N-acetyltransferase of Mycobacterium tuberculosis is a polymorphic enzyme and a site of isoniazid metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

GSTM1 null genotype, red meat consumption and breast cancer risk (The Netherlands).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Diverse point mutations in the human gene for polymorphic N-acetyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Nomenclature for N-acetyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Variation in enzymes of arylamine procarcinogen biotransformation among bladder cancer patients and control subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Sequence-ready contig for the 1.4-cM ductal carcinoma in situ loss of heterozygosity region on chromosome 8p22-p23.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Probing the mechanism of hamster arylamine N-acetyltransferase 2 acetylation by active site modification, site-directed mutagenesis, and pre-steady state and steady state kinetic studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Longitudinal distribution of arylamine N-acetyltransferases in the intestine of the hamster, mouse, and rat. Evidence for multiplicity of N-acetyltransferases in the intestine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Sensitive method for the detection of mutagenic nitroarenes and aromatic amines: new derivatives of Salmonella typhimurium tester strains possessing elevated O-acetyltransferase levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

A perspective on the history and significance of carcinogenic and mutagenic N-substituted aryl compounds in human health.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Relationship between acetylator status, smoking, and diet and colorectal cancer risk in the north-east of England.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Expression, purification, characterization and structure of Pseudomonas aeruginosa arylamine N-acetyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Relevance of N-acetyltransferase 1 and 2 (NAT1, NAT2) genetic polymorphisms in non-small cell lung cancer susceptibility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

N-Acetyltransferases, sulfotransferases and heterocyclic amine activation in the breast.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

The role of xenobiotic metabolizing enzymes in arylamine toxicity and carcinogenesis: functional and localization studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Cytochrome P450 monooxygenases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Lack of association between arylamine N-acetyltransferase 2 (NAT2) polymorphism and systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Evidence towards the role of arylamine N-acetyltransferase in Mycobacterium smegmatis and development of a specific antiserum against the homologous enzyme of Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Rapid Detection of CYP1A1, CYP2D6, and NAT Variants by Multiplex Polymerase Chain Reaction and Allele-Specific Oligonucleotide Assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Association between endometriosis and N-acetyl transferase 2 polymorphisms in a UK population

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

A prospective study of NAT2 acetylation genotype, cigarette smoking, and risk of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

Genetically based N-acetyltransferase metabolic polymorphism and low-level environmental exposure to carcinogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F03602530500251204

10.1080/03602530500251204

21 January 2018

Identifiers

DOI

1 reference

13 August 2017

1 reference

PubMed ID

16257833