Genetic polymorphisms of ATP-binding cassette transporters ABCB1 and ABCG2: therapeutic implications (Q36301589)

13 August 2017

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title

Genetic polymorphisms of ATP-binding cassette transporters ABCB1 and ABCG2: therapeutic implications (English)

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13 August 2017

4

Toshihisa Ishikawa

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13 August 2017

Aki Sakurai

1

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13 August 2017

Ai Tamura

series ordinal

2

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13 August 2017

Yuko Onishi

series ordinal

3

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13 August 2017

language of work or name

English

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publication date

1 November 2005

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Expert Opinion on Pharmacotherapy

13 August 2017

published in

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13 August 2017

volume

6

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13 August 2017

issue

14

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13 August 2017

page(s)

2455-2473

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dbSNP: a database of single nucleotide polymorphisms

13 August 2017

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Tacrolimus pharmacogenetics: polymorphisms associated with expression of cytochrome p4503A5 and P-glycoprotein correlate with dose requirement

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The effects of the human MDR1 genotype on the expression of duodenal P-glycoprotein and disposition of the probe drug talinolol.

21 January 2018

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A common P-glycoprotein polymorphism is associated with nortriptyline-induced postural hypotension in patients treated for major depression

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MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine

21 January 2018

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Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study

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Effect of the mutation (C3435T) at exon 26 of the MDR1 gene on expression level of MDR1 messenger ribonucleic acid in duodenal enterocytes of healthy Japanese subjects.

21 January 2018

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21 January 2018

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Genetic polymorphisms in MDR1 and CYP3A4 genes in Asians and the influence of MDR1 haplotypes on cyclosporin disposition in heart transplant recipients

21 January 2018

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Role of human MDR1 gene polymorphism in bioavailability and interaction of digoxin, a substrate of P-glycoprotein.

21 January 2018

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Dipyridamole enhances digoxin bioavailability via P-glycoprotein inhibition

21 January 2018

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Explaining interindividual variability of docetaxel pharmacokinetics and pharmacodynamics in Asians through phenotyping and genotyping strategies

21 January 2018

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C3435T polymorphism in the MDR1 gene affects the enterocyte expression level of CYP3A4 rather than Pgp in recipients of living-donor liver transplantation

21 January 2018

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Neurotoxicity induced by tacrolimus after liver transplantation: relation to genetic polymorphisms of the ABCB1 (MDR1) gene

21 January 2018

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Single nucleotide polymorphisms of ABCB1 (MDR1) gene and distinct haplotype profile in a West Black African population

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Digoxin up-regulates multidrug resistance transporter (MDR1) mRNA and simultaneously down-regulates steroid xenobiotic receptor mRNA.

21 January 2018

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Levothyroxine up-regulates P-glycoprotein independent of the pregnane X receptor

21 January 2018

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Antimalarial artemisinin drugs induce cytochrome P450 and MDR1 expression by activation of xenosensors pregnane X receptor and constitutive androstane receptor.

21 January 2018

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A multidrug resistance transporter from human MCF-7 breast cancer cells

21 January 2018

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Molecular and cytogenetic characterization of the mouse ATP-binding cassette transporter Abcg4.

21 January 2018

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Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2)

21 January 2018

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ABCG2 -- a transporter for all seasons

21 January 2018

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The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins into milk.

21 January 2018

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The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype

21 January 2018

1 reference

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Bcrp1 gene expression is required for normal numbers of side population stem cells in mice, and confers relative protection to mitoxantrone in hematopoietic cells in vivo

21 January 2018

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The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria.

21 January 2018

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The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme

21 January 2018

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21 January 2018

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21 January 2018

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Cutaneous hyperpigmentation during therapy with hydroxychloroquine

21 January 2018

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Single-nucleotide polymorphism (SNP) analysis in the ABC half-transporter ABCG2 (MXR/BCRP/ABCP1).

21 January 2018

1 reference

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Catalog of 605 single-nucleotide polymorphisms (SNPs) among 13 genes encoding human ATP-binding cassette transporters: ABCA4, ABCA7, ABCA8, ABCD1, ABCD3, ABCD4, ABCE1, ABCF1, ABCG1, ABCG2, ABCG4, ABCG5, and ABCG8

21 January 2018

1 reference

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Natural allelic variants of breast cancer resistance protein (BCRP) and their relationship to BCRP expression in human intestine.

21 January 2018

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Eight novel single nucleotide polymorphisms in ABCG2/BCRP in Japanese cancer patients administered irinotacan

21 January 2018

1 reference

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Genetic variation in the ATP-binding Cassette Transporter gene ABCG2 (BCRP) in a Swedish population

21 January 2018

1 reference

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ABCG2 pharmacogenetics: ethnic differences in allele frequency and assessment of influence on irinotecan disposition

21 January 2018

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Functional assessment of ABCG2 (BCRP) gene polymorphisms to protein expression in human placenta.

21 January 2018

1 reference

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Single nucleotide polymorphisms result in impaired membrane localization and reduced atpase activity in multidrug transporter ABCG2.

21 January 2018

1 reference

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Single nucleotide polymorphisms modify the transporter activity of ABCG2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.6.14.2455

Detection of single nucleotide polymorphisms in the ABCG2 gene in a Dutch population

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.6.14.2455

Functional analysis of SNPs variants of BCRP/ABCG2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.6.14.2455

A functional study on polymorphism of the ATP-binding cassette transporter ABCG2: critical role of arginine-482 in methotrexate transport.

21 January 2018

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Transport function and substrate specificity of multidrug resistance protein

21 January 2018

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Single amino acid (482) variants of the ABCG2 multidrug transporter: major differences in transport capacity and substrate recognition

21 January 2018

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Reversal of breast cancer resistance protein (BCRP/ABCG2)‐mediated drug resistance by novobiocin, a coumermycin antibiotic

21 January 2018

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Flavonoids are inhibitors of breast cancer resistance protein (ABCG2)-mediated transport

21 January 2018

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Combined effects of multiple flavonoids on breast cancer resistance protein (ABCG2)-mediated transport

21 January 2018

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Phytoestrogens/flavonoids reverse breast cancer resistance protein/ABCG2-mediated multidrug resistance.

21 January 2018

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Flavonoid structure-activity studies identify 6-prenylchrysin and tectochrysin as potent and specific inhibitors of breast cancer resistance protein ABCG2.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14656566.6.14.2455

Protein kinase inhibitors: insights into drug design from structure.

21 January 2018

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High-affinity interaction of tyrosine kinase inhibitors with the ABCG2 multidrug transporter

21 January 2018

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Gefitinib ("Iressa", ZD1839), an epidermal growth factor receptor tyrosine kinase inhibitor, reverses breast cancer resistance protein/ABCG2-mediated drug resistance.

21 January 2018

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Gefitinib enhances the antitumor activity and oral bioavailability of irinotecan in mice

21 January 2018

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Multidrug transporter ABCG2 prevents tumor cell death induced by the epidermal growth factor receptor inhibitor Iressa (ZD1839, Gefitinib).

21 January 2018

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Imatinib mesylate is a potent inhibitor of the ABCG2 (BCRP) transporter and reverses resistance to topotecan and SN-38 in vitro

21 January 2018

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Imatinib mesylate (STI571) is a substrate for the breast cancer resistance protein (BCRP)/ABCG2 drug pump

21 January 2018

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Novel camptothecin analogues that circumvent ABCG2-associated drug resistance in human tumor cells.

21 January 2018

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Pharmacogenomics in Drug Development and Regulatory Decision-making: the Genomic Data Submission (GDS) Proposal

21 January 2018

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Influence of polymorphisms within the CX3CR1 and MDR-1 genes on initial antiretroviral therapy response

21 January 2018

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Association of Multidrug Resistance in Epilepsy with a Polymorphism in the Drug-Transporter GeneABCB1

21 January 2018

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The Effect of CYP3A5 and MDR1 Polymorphic Expression on Cyclosporine Oral Disposition in Renal Transplant Patients

21 January 2018

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10.1517/14656566.6.14.2455

21 January 2018

Identifiers

DOI

1 reference

13 August 2017

1 reference