Mechanisms of disease: The role of hepcidin in iron homeostasis--implications for hemochromatosis and other disorders (Q36304041)

13 August 2017

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title

Mechanisms of disease: The role of hepcidin in iron homeostasis--implications for hemochromatosis and other disorders (English)

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13 August 2017

Antonello Pietrangelo

series ordinal

1

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13 August 2017

Christian Trautwein

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2

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13 August 2017

language of work or name

English

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publication date

1 November 2004

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Nature Reviews Gastroenterology & Hepatology

13 August 2017

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13 August 2017

1

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13 August 2017

39-45

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13 August 2017

1

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https://scigraph.springernature.com/pub.10.1038/ncpgasthep0019

13 August 2017

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cites work

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A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload

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Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice

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Disruption of ferroportin 1 regulation causes dynamic alterations in iron homeostasis and erythropoiesis in polycythaemia mice

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The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation

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Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein

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IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin

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The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22.

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7 January 2021

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Iron homeostasis: insights from genetics and animal models

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Hepcidin expression inversely correlates with the expression of duodenal iron transporters and iron absorption in rats

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Hepcidin, a new iron regulatory peptide

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7 January 2021

Decreased hepcidin mRNA expression in thalassemic mice

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7 January 2021

Constitutive hepcidin expression prevents iron overload in a mouse model of hemochromatosis

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7 January 2021

Identifiers

DOI

10.1038/NCPGASTHEP0019

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Dimensions Publication ID

13 August 2017

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