Drug insight: If inhibitors as specific heart-rate-reducing agents (Q36304200)

13 August 2017

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title

Drug insight: If inhibitors as specific heart-rate-reducing agents (English)

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13 August 2017

Jeffrey S Borer

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13 August 2017

1 December 2004

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Nature Clinical Practice Cardiovascular Medicine

13 August 2017

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13 August 2017

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13 August 2017

103-109

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13 August 2017

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https://scigraph.springernature.com/pub.10.1038/ncpcardio0052

13 August 2017

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cites work

Importance of heart rate in determining beta-blocker efficacy in acute and long-term acute myocardial infarction intervention trials

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0052

Rest heart rate and life expectancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0052

The cardiac hyperpolarizing-activated current, if. Origins and developments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0052

Guidelines for the management of patients with chronic stable angina: diagnosis and risk stratification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0052

Characteristics of a contemporary population with angina pectoris. TIDES Investigators.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0052

How does adrenaline accelerate the heart?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0052

Direct activation of cardiac pacemaker channels by intracellular cyclic AMP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0052

A family of hyperpolarization-activated mammalian cation channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0052

Inhibition of the hyperpolarization-activated current (if) induced by acetylcholine in rabbit sino-atrial node myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0052

The contribution of the 'pacemaker' current (if) to generation of spontaneous activity in rabbit sino-atrial node myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0052

Contributions of heart rate and contractility to myocardial oxygen balance during exercise

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0052

Effect of Graded Heart Rate Reduction with Ivabradine on Myocardial Oxygen Consumption and Diastolic Time in Exercising Dogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0052

Left ventricular muscle mass and elevated heart rate are associated with coronary plaque disruption.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0052

Differential effects of heart rate reduction and beta-blockade on left ventricular relaxation during exercise

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0052

Long-term heart rate reduction induced by the selective I(f) current inhibitor ivabradine improves left ventricular function and intrinsic myocardial structure in congestive heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0052

Induction of insulin resistance by beta-blockade but not ACE-inhibition: long-term treatment with atenolol or trandolapril.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0052

Effects of antihypertensives on plasma lipids and lipoprotein metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0052

Adverse reactions with beta-adrenoceptor blocking drugs. An update

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0052

Addition of zatebradine, a direct sinus node inhibitor, provides no greater exercise tolerance benefit in patients with angina taking extended-release nifedipine: results of a multicenter, randomized, double-blind, placebo-controlled, parallel-group

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0052

Electrophysiological effects of S 16257, a novel sino-atrial node modulator, on rabbit and guinea-pig cardiac preparations: comparison with UL-FS 49

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0052

Mode of action of bradycardic agent, S 16257, on ionic currents of rabbit sinoatrial node cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0052

Current-dependent block of rabbit sino-atrial node I(f) channels by ivabradine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0052

Anti-Ischemic Effects of Ivabradine, a Selective Heart Rate-Reducing Agent, in Exercise-Induced Myocardial Ischemia in Pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0052

A single intravenous dose of ivabradine, a novel I(f) inhibitor, lowers heart rate but does not depress left ventricular function in patients with left ventricular dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0052

Heart rate lowering by specific and selective I(f) current inhibition with ivabradine: a new therapeutic perspective in cardiovascular disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0052

Development of cardiovascular drugs: the U.S. regulatory milieu from the perspective of a participating nonregulator.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0052

Antianginal and antiischemic effects of ivabradine, an I(f) inhibitor, in stable angina: a randomized, double-blind, multicentered, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0052

Characterization of single pacemaker channels in cardiac sino-atrial node cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0052

The epidemiology of resting heart rate in a national sample of men and women: associations with hypertension, coronary heart disease, blood pressure, and other cardiovascular risk factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0052

7 January 2021

Management of stable angina pectoris. Recommendations of the Task Force of the European Society of Cardiology

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0052

7 January 2021

ACC/AHA/ACP-ASIM guidelines for the management of patients with chronic stable angina: executive summary and recommendations. A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on M

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0052

7 January 2021

Respiratory function in the elderly and the effects of beta blockade

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0052

7 January 2021

Transient myocardial ischemia after abrupt withdrawal of antianginal therapy in chronic stable angina

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0052

7 January 2021

Acute and chronic antianginal efficacy of continuous twenty-four-hour application of transdermal nitroglycerin. Steering Committee, Transdermal Nitroglycerin Cooperative Study

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0052

7 January 2021

Frequency and cost of serious adverse drug reactions in a department of general medicine

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO0052

7 January 2021

Identifiers

DOI

10.1038/NCPCARDIO0052

1 reference

PubMed ID

16265314

Dimensions Publication ID

13 August 2017

0 references

1 reference

PubMed ID

16265314