Efficient nonviral Sleeping Beauty transposon-based TCR gene transfer to peripheral blood lymphocytes confers antigen-specific antitumor reactivity. (Q36311669)

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English	Efficient nonviral Sleeping Beauty transposon-based TCR gene transfer to peripheral blood lymphocytes confers antigen-specific antitumor reactivity.	scientific article

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scholarly article

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30 January 2020

Efficient nonviral Sleeping Beauty transposon-based TCR gene transfer to peripheral blood lymphocytes confers antigen-specific antitumor reactivity (English)

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30 January 2020

0 references

Sleeping Beauty transposon system

1 reference

based on heuristic

inferred from title

2

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30 January 2020

5

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30 January 2020

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30 January 2020

author name string

P D Peng

1

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30 January 2020

S Yang

3

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30 January 2020

C Hsu

4

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30 January 2020

Z Zheng

7

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30 January 2020

S A Rosenberg

8

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30 January 2020

R A Morgan

9

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publication date

4 June 2009

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30 January 2020

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16

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30 January 2020

8

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30 January 2020

1042-1049

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30 January 2020

https://scigraph.springernature.com/pub.10.1038/gt.2009.54

0 references

Adoptive immunotherapy for indolent non-Hodgkin lymphoma and mantle cell lymphoma using genetically modified autologous CD20-specific T cells

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30 September 2017

Redirecting specificity of T-cell populations for CD19 using the Sleeping Beauty system

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30 September 2017

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30 September 2017

Sleeping Beauty transposon-mediated engineering of human primary T cells for therapy of CD19+ lymphoid malignancies

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30 September 2017

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30 September 2017

Targeted Sleeping Beauty transposition in human cells

1 reference

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30 September 2017

Site-directed transposon integration in human cells

1 reference

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30 September 2017

Transposons for gene therapy!

1 reference

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30 September 2017

A phase I study on adoptive immunotherapy using gene-modified T cells for ovarian cancer

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30 September 2017

Gene transfer of tumor-reactive TCR confers both high avidity and tumor reactivity to nonreactive peripheral blood mononuclear cells and tumor-infiltrating lymphocytes

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30 September 2017

Enhanced antitumor activity of murine-human hybrid T-cell receptor (TCR) in human lymphocytes is associated with improved pairing and TCR/CD3 stability

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30 September 2017

Cancer regression in patients after transfer of genetically engineered lymphocytes

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30 September 2017

Sustained FVIII expression and phenotypic correction of hemophilia A in neonatal mice using an endothelial-targeted sleeping beauty transposon

1 reference

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30 September 2017

RNA as a source of transposase for Sleeping Beauty-mediated gene insertion and expression in somatic cells and tissues

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30 September 2017

Supernatural T cells: genetic modification of T cells for cancer therapy

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30 September 2017

Recognition of fresh human tumor by human peripheral blood lymphocytes transduced with a bicistronic retroviral vector encoding a murine anti-p53 TCR.

1 reference

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30 September 2017

High-efficiency transfection of primary human and mouse T lymphocytes using RNA electroporation

1 reference

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30 September 2017

Sleeping beauty transposon-mediated gene therapy for prolonged expression

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30 September 2017

Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cells

1 reference

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30 September 2017

Transfer of a TCR gene derived from a patient with a marked antitumor response conveys highly active T-cell effector functions

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469249

30 September 2017

Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma

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30 September 2017

Primary human lymphocytes transduced with NY-ESO-1 antigen-specific TCR genes recognize and kill diverse human tumor cell lines

1 reference

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30 September 2017

High-resolution genome-wide mapping of transposon integration in mammals

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30 September 2017

Mutational analysis of the N-terminal DNA-binding domain of sleeping beauty transposase: critical residues for DNA binding and hyperactivity in mammalian cells

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30 September 2017

Development of hyperactive sleeping beauty transposon vectors by mutational analysis

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30 September 2017

High efficiency TCR gene transfer into primary human lymphocytes affords avid recognition of melanoma tumor antigen glycoprotein 100 and does not alter the recognition of autologous melanoma antigens

1 reference

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30 September 2017

Gene transfer into genomes of human cells by the sleeping beauty transposon system.

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30 September 2017

Transcription start regions in the human genome are favored targets for MLV integration

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30 September 2017

Human T lymphocytes transduced by lentiviral vectors in the absence of TCR activation maintain an intact immune competence

1 reference

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30 September 2017

Mechanisms that regulate silencing of gene expression from retroviral vectors

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30 September 2017

Silencing of gene expression: implications for design of retrovirus vectors

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30 September 2017

Stable gene transfer and expression in human primary T cells by the Sleeping Beauty transposon system

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29 June 2018

Sustainable correction of junctional epidermolysis bullosa via transposon-mediated nonviral gene transfer

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29 June 2018

Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system

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29 June 2018

The use of anti-CD3 and anti-CD28 monoclonal antibodies to clone and expand human antigen-specific T cells

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29 June 2018

Target-site preferences of Sleeping Beauty transposons.

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22 September 2018

Correction of multi-gene deficiency in vivo using a single 'self-cleaving' 2A peptide-based retroviral vector

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22 September 2018

Lentivirus vector-mediated expression of tumor-associated epitopes by human antigen presenting cells.

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22 September 2018

Lentivirus-mediated gene transfer and expression in established human tumor antigen-specific cytotoxic T cells and primary unstimulated T cells.

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22 September 2018

Immunological and clinical responses in metastatic renal cancer patients vaccinated with tumor RNA-transfected dendritic cells

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22 September 2018

Cooperation of Human Tumor-Reactive CD4+ and CD8+ T Cells after Redirection of Their Specificity by a High-Affinity p53A2.1-Specific TCR

1 reference

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12 December 2020

based on heuristic

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Treatment of metastatic renal cell carcinoma with autologous T-lymphocytes genetically retargeted against carbonic anhydrase IX: first clinical experience

1 reference

https://pubmed.ncbi.nlm.nih.gov/19494842

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adoptive transfer of chimeric antigen receptor re-directed cytolytic T lymphocyte clones in patients with neuroblastoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19494842

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/GT.2009.54

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30 January 2020

1 reference

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30 January 2020

1 reference

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30 January 2020

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