Development of transcriptionally regulated oncolytic adenoviruses (Q36318182)

13 August 2017

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title

Development of transcriptionally regulated oncolytic adenoviruses (English)

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13 August 2017

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Derek Ko

1

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13 August 2017

Lynda Hawkins

series ordinal

2

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13 August 2017

De-Chao Yu

series ordinal

3

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13 August 2017

language of work or name

English

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publication date

1 November 2005

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13 August 2017

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13 August 2017

24

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13 August 2017

52

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13 August 2017

7763-7774

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1209048

13 August 2017

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cites work

Transcriptional control by E2F.

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Spliced segments at the 5′ terminus of adenovirus 2 late mRNA

21 January 2018

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Insertion of the adenoviral E3 region into a recombinant viral vector prevents antiviral humoral and cellular immune responses and permits long-term gene expression

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

Adenovirus E3-6.7K protein is required in conjunction with the E3-RID protein complex for the internalization and degradation of TRAIL receptor 2

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

Adenovirus RIDbeta subunit contains a tyrosine residue that is critical for RID-mediated receptor internalization and inhibition of Fas- and TRAIL-induced apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

DNA tumor virus oncoproteins and retinoblastoma gene mutations share the ability to relieve the cell's requirement for cyclin D1 function in G1

21 January 2018

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The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and Bcl-2 proteins

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

Prostate-specific antigen expression is regulated by an upstream enhancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

Deletion of penton RGD motifs affects the efficiency of both the internalization and the endosome escape of viral particles containing adenovirus serotype 5 or 35 fiber knobs

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

The murine double-stranded RNA-dependent protein kinase PKR is required for resistance to vesicular stomatitis virus.

21 January 2018

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Innate immune mechanisms dominate elimination of adenoviral vectors following in vivo administration.

21 January 2018

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Linked tumor-selective virus replication and transgene expression from E3-containing oncolytic adenoviruses

21 January 2018

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Oncolytic viral therapies - the clinical experience

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

Adenovirus proteins from both E1B reading frames are required for transformation of rodent cells by viral infection and DNA transfection

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

Studies of adenoviruses (APC) in volunteers

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

Pre-early adenovirus 5 gene product regulates synthesis of early viral messenger RNAs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

Recent lessons in gene expression, cell cycle control, and cell biology from adenovirus

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

Linking colorectal cancer to Wnt signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

An adenovirus mutant that replicates selectively in p53-deficient human tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

In vitro and in vivo activities of an oncolytic adenoviral vector designed to express GM-CSF.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

Oncolytic adenovirus CG7870 in combination with radiation demonstrates synergistic enhancements of antitumor efficacy without loss of specificity

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

An adenovirus vector with genetically modified fibers demonstrates expanded tropism via utilization of a coxsackievirus and adenovirus receptor-independent cell entry mechanism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

Nuclear export of the E1B 55-kDa and E4 34-kDa adenoviral oncoproteins mediated by a rev-like signal sequence

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

Polymer-coated adenovirus permits efficient retargeting and evades neutralising antibodies.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

Vesicular stomatitis virus: an exciting new therapeutic oncolytic virus candidate for cancer or just another chapter from Field's Virology?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

A 14,700 MW protein from the E3 region of adenovirus inhibits cytolysis by tumor necrosis factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

Extended plasma circulation time and decreased toxicity of polymer-coated adenovirus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

Interaction of E1B 19K with Bax is required to block Bax-induced loss of mitochondrial membrane potential and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

Adenovirus E1A under the control of heterologous promoters: wide variation in E1A expression levels has little effect on virus replication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

Identification of distinct roles for separate E1A domains in disruption of E2F complexes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

Cellular immortalization by a cDNA clone encoding the transformation-associated phosphoprotein p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

Selectively replicating adenoviruses targeting deregulated E2F activity are potent, systemic antitumor agents

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

Replication-selective oncolytic adenoviruses: virotherapy aimed at genetic targets in cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

The adenovirus E3-14.5K protein which is required for prevention of TNF cytolysis and for down-regulation of the EGF receptor contains phosphoserine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

High-level, beta-catenin/TCF-dependent transgene expression in secondary colorectal cancer tissue

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

Effect of inoculating adenovirus (APC virus) type 8 into human volunteers.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

Mechanism of activation of early viral transcription by the adenovirus E1A gene product

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

The adenovirus E4-6/7 protein transactivates the E2 promoter by inducing dimerization of a heteromeric E2F complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

Adenoviral proteins mimic nutrient/growth signals to activate the mTOR pathway for viral replication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

Late viral RNA export, rather than p53 inactivation, determines ONYX-015 tumor selectivity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

Tumor-selective transgene expression in vivo mediated by an E2F-responsive adenoviral vector.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

Intravascular adenoviral agents in cancer patients: lessons from clinical trials

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

Creation of a new transgene cloning site near the right ITR of Ad5 results in reduced enhancer interference with tissue-specific and regulatable promoters

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

Antitumor efficacy and tumor-selective replication with a single intravenous injection of OAS403, an oncolytic adenovirus dependent on two prevalent alterations in human cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

Adenovirus E1b-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kd cellular protein in transformed cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

An oncolytic adenovirus vector combining enhanced cell-to-cell spreading, mediated by the ADP cytolytic protein, with selective replication in cancer cells with deregulated wnt signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

Oncolytic herpes simplex virus vectors for cancer virotherapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

Effects of innate immunity on herpes simplex virus and its ability to kill tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

Production of pharyngoconjunctival fever in human volunteers inoculated with APC viruses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

Inhibition of p53 transactivation required for transformation by adenovirus early 1B protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

Tissue-specific and hormonal regulation of human prostate-specific glandular kallikrein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

Novel type I interferon IL-28A suppresses hepatitis C viral RNA replication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209048

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209048

1 reference

13 August 2017

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