New and improved glucocorticoid receptor ligands (Q36322079)

13 August 2017

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title

New and improved glucocorticoid receptor ligands (English)

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13 August 2017

Jeffrey N Miner

1

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13 August 2017

Mei Hua Hong

series ordinal

2

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13 August 2017

Andrés Negro-Vilar

series ordinal

3

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13 August 2017

language of work or name

English

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publication date

1 December 2005

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Expert Opinion on Investigational Drugs

13 August 2017

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13 August 2017

14

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13 August 2017

12

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13 August 2017

1527-1545

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Anniversary: 50 years of glucocorticoid treatment in rheumatoid arthritis.

13 August 2017

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Fifty years of experience with cortisone therapy in the study and treatment of rheumatoid arthritis

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The origin and functions of multiple human glucocorticoid receptor isoforms

21 January 2018

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Novel glucocorticoid receptor coactivator effector mechanisms

21 January 2018

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Glucocorticoid therapy for immune-mediated diseases: basic and clinical correlates

21 January 2018

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A randomised controlled trial of short term growth and collagen turnover in asthmatics treated with inhaled formoterol and budesonide

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Corticosterone is permissive to the anxiolytic effect that results from the blockade of hippocampal mineralocorticoid receptors

21 January 2018

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Kinetics of in vivo muscle insulin-mediated glucose uptake in human obesity

21 January 2018

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Multihormonal regulation of phosphoenolpyruvate carboxykinase gene transcription. The dominant role of insulin

21 January 2018

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Corticosteroids and peptic ulcer: meta-analysis of adverse events during steroid therapy.

21 January 2018

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Stress and lipoprotein metabolism: modulators and mechanisms

21 January 2018

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Insights Into Glucocorticoid-Associated Hypertension

21 January 2018

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Role of myostatin in metabolism

21 January 2018

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Surgical Management of Complications of Steroid Therapy

21 January 2018

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Bone histomorphometry in glucocorticoid-induced osteoporosis

21 January 2018

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Tandem repeat of C/EBP binding sites mediates PPARgamma2 gene transcription in glucocorticoid-induced adipocyte differentiation

21 January 2018

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Dexamethasone induces proliferation and terminal differentiation of osteogenic cells in tissue culture

21 January 2018

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Synthetic peptide containing Arg-Gly-Asp inhibits bone formation and resorption in a mineralizing organ culture system of fetal rat parietal bones

21 January 2018

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Immunogold localization of beta 1-integrin in bone: effect of glucocorticoids and insulin-like growth factor I on integrins and osteocyte formation.

21 January 2018

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The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption.

21 January 2018

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Glucocorticoid decreases circulating osteoprotegerin (OPG): possible mechanism for glucocorticoid induced osteoporosis

21 January 2018

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1,25-dihydroxyvitamin D-responsive element and glucocorticoid repression in the osteocalcin gene

21 January 2018

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Cortisol downregulates osteoblast alpha 1 (I) procollagen mRNA by transcriptional and posttranscriptional mechanisms.

21 January 2018

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Glucocorticoid regulation of alkaline phosphatase, osteocalcin, and proto-oncogenes in normal human osteoblast-like cells

21 January 2018

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The growth-supportive effect of thrombospondin (TSP1) and the expression of TSP1 by human MG-63 osteoblastic cells are both inhibited by dexamethasone

21 January 2018

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Apoptosis and osteoporosis

21 January 2018

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Prevention and treatment of osteoporosis: efficacy of combination of hormone replacement therapy with other antiresorptive agents

21 January 2018

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Effects off short term glucocorticoid administration on intestinal calcium absorption and circulating vitamin D metabolite concentrations in man.

21 January 2018

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Osteonecrosis: current perspectives on pathogenesis and treatment

21 January 2018

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Nontraumatic necrosis of bone (osteonecrosis).

21 January 2018

1 reference

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Effects of dexamethasone on proliferation, activity, and cytokine secretion of normal human bone marrow stromal cells: possible mechanisms of glucocorticoid-induced bone loss

21 January 2018

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Regulatory crosstalk at composite response elements

21 January 2018

1 reference

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Transcription factor interactions: selectors of positive or negative regulation from a single DNA element.

21 January 2018

1 reference

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The basic region of AP-1 specifies glucocorticoid receptor activity at a composite response element

21 January 2018

1 reference

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Modeling of corticosteroid pharmacogenomics in rat liver using gene microarrays

21 January 2018

1 reference

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Steroid hormone receptors and in vitro transcription

21 January 2018

1 reference

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An additional region of coactivator GRIP1 required for interaction with the hormone-binding domains of a subset of nuclear receptors

21 January 2018

1 reference

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CREB binding protein acts synergistically with steroid receptor coactivator-1 to enhance steroid receptor-dependent transcription

21 January 2018

1 reference

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Structure and specificity of nuclear receptor-coactivator interactions

21 January 2018

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Gene repression by nuclear hormone receptors

21 January 2018

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Glucocorticoid-mediated repression of nuclear factor-kappaB-dependent transcription involves direct interference with transactivation

21 January 2018

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DNA binding of the glucocorticoid receptor is not essential for survival

21 January 2018

1 reference

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Ligand-activated retinoic acid receptor inhibits AP-1 transactivation by disrupting c-Jun/c-Fos dimerization.

21 January 2018

1 reference

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Glucocorticoid-dependent transcriptional repression of the osteocalcin gene by competitive binding at the TATA box.

21 January 2018

1 reference

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I kappaB alpha-independent downregulation of NF-kappaB activity by glucocorticoid receptor.

21 January 2018

1 reference

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The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain

21 January 2018

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A nuclear isoform of the focal adhesion LIM-domain protein Trip6 integrates activating and repressing signals at AP-1- and NF-kappaB-regulated promoters

21 January 2018

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The glucocorticoid receptor: rapid exchange with regulatory sites in living cells

21 January 2018

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Factor recruitment and TIF2/GRIP1 corepressor activity at a collagenase-3 response element that mediates regulation by phorbol esters and hormones

21 January 2018

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Glucocorticoid receptor-JNK interaction mediates inhibition of the JNK pathway by glucocorticoids.

21 January 2018

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Glucocorticoid resistance and hypersensitivity

21 January 2018

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Effects of alendronate on bone quality and remodeling in glucocorticoid-induced osteoporosis: a histomorphometric analysis of transiliac biopsies

21 January 2018

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Hypothalamic origin of the metabolic syndrome X.

21 January 2018

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A nonsteroidal glucocorticoid receptor antagonist

21 January 2018

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Bile acid conjugates of a nonsteroidal glucocorticoid receptor modulator.

21 January 2018

1 reference

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Selective glucocorticoid receptor nonsteroidal ligands completely antagonize the dexamethasone mediated induction of enzymes involved in gluconeogenesis and glutamine metabolism.

21 January 2018

1 reference

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The antibiotic rifampicin is a nonsteroidal ligand and activator of the human glucocorticoid receptor

21 January 2018

1 reference

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Novel glucocorticoid antedrugs possessing a 17beta-(gamma-lactone) ring.

21 January 2018

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Recent advances in retrometabolic design approaches.

21 January 2018

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Complete remission of experimental arthritis by joint targeting of glucocorticoids with long-circulating liposomes

21 January 2018

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Nitric oxide synthase inhibitors have opposite effects on acute inflammation depending on their route of administration.

21 January 2018

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21-NO-prednisolone is a novel nitric oxide-releasing derivative of prednisolone with enhanced anti-inflammatory properties

21 January 2018

1 reference

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Potent antiarthritic properties of a glucocorticoid derivative, NCX-1015, in an experimental model of arthritis

21 January 2018

1 reference

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Hormone-dependent coactivator binding to a hydrophobic cleft on nuclear receptors

21 January 2018

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Selective androgen receptor modulators (SARMs): a novel approach to androgen therapy for the new millennium

21 January 2018

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Molecular mechanisms of action of steroid/thyroid receptor superfamily members

21 January 2018

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Differentiation of in vitro transcriptional repression and activation profiles of selective glucocorticoid modulators

21 January 2018

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trans-Activation and repression properties of the novel nonsteroid glucocorticoid receptor ligand 2,5-dihydro-9-hydroxy-10-methoxy-2,2,4-trimethyl-5-(1-methylcyclohexen-3-y1)-1H-[1]benzopyrano[3,4-f]quinoline (A276575) and its four stereoisomers

21 January 2018

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A novel antiinflammatory maintains glucocorticoid efficacy with reduced side effects

21 January 2018

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Dissociation of transactivation from transrepression by a selective glucocorticoid receptor agonist leads to separation of therapeutic effects from side effects

21 January 2018

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Oral corticosteroids and fracture risk: relationship to daily and cumulative doses

21 January 2018

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Equivalence trials in SLE research: issues to consider

21 January 2018

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10.1517/13543784.14.12.1527

21 January 2018

Identifiers

DOI

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13 August 2017

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