Emerging challenges in ligand discovery: new opportunities for chromatographic assay (Q36322152)

13 August 2017

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title

Emerging challenges in ligand discovery: new opportunities for chromatographic assay (English)

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13 August 2017

Ella Ng

1

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13 August 2017

David C Schriemer

series ordinal

2

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13 August 2017

publication date

1 December 2005

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Expert Review of Proteomics

13 August 2017

published in

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13 August 2017

volume

2

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13 August 2017

issue

6

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13 August 2017

page(s)

891-900

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Prospects and challenges of developing new agents for tough Gram-negatives

13 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Drug discovery and beyond: the role of public-private partnerships in improving access to new malaria medicines

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

How many genomics targets can a portfolio afford?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Drug discovery in academia

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Development of a large-scale chemogenomics database to improve drug candidate selection and to understand mechanisms of chemical toxicity and action

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Mitosis: a history of division

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Multidimensional chemical genetic analysis of diversity-oriented synthesis-derived deacetylase inhibitors using cell-based assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Chemical genetic modifier screens: small molecule trichostatin suppressors as probes of intracellular histone and tubulin acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

High-throughput kinase assays with protein substrates using fluorescent polymer superquenching

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Frontal affinity chromatography with MS detection of EphB2 tyrosine kinase receptor. 2. Identification of small-molecule inhibitors via coupling with virtual screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Recent advances in the development of selective small molecule inhibitors for cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Selective benzopyranone and pyrimido[2,1-a]isoquinolin-4-one inhibitors of DNA-dependent protein kinase: synthesis, structure-activity studies, and radiosensitization of a human tumor cell line in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Interaction profiles of protein kinase-inhibitor complexes and their application to virtual screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Library design for fragment based screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Neighborhood behavior: a useful concept for validation of "molecular diversity" descriptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Lessons from natural molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Natural products as a resource for new drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Natural products and combinatorial chemistry: back to the future

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Anomeric reactivity-based one-pot oligosaccharide synthesis: a rapid route to oligosaccharide libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Characterization of SH2-ligand interactions via library affinity selection with mass spectrometric detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Mass spectrometry and immobilized enzymes for the screening of inhibitor libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Biochemical applications of mass spectrometry in pharmaceutical drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Early discovery drug screening using mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Surface plasmon resonance mass spectrometry: recent progress and outlooks

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Displacement and nonlinear chromatographic techniques in the investigation of interaction of noncompetitive inhibitors with an immobilized alpha3beta4 nicotinic acetylcholine receptor liquid chromatographic stationary phase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Immobilized nicotinic receptor stationary phases: going with the flow in high-throughput screening and pharmacological studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Conformational mobility of immobilized alpha3beta2, alpha3beta4, alpha4beta2, and alpha4beta4 nicotinic acetylcholine receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Multiple receptor liquid chromatographic stationary phases: the co-immobilization of nicotinic receptors, gamma-amino-butyric acid receptors, and N-methyl D-aspartate receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Affinity selection and mass spectrometry-based strategies to identify lead compounds in combinatorial libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Affinity selection from peptide libraries to determine substrate specificity of protein tyrosine phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

A general technique to rank protein-ligand binding affinities and determine allosteric versus direct binding site competition in compound mixtures

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Frontal affinity chromatography-mass spectrometry assay technology for multiple stages of drug discovery: applications of a chromatographic biosensor

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Frontal affinity chromatography for the screening of mixtures

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Global kinase screening. Applications of frontal affinity chromatography coupled to mass spectrometry in drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Estimation of drug-protein binding parameters on assuming the validity of thermodynamic equilibrium

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Quantitative analysis of allosteric drug-protein binding by biointeraction chromatography.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Frontal affinity chromatography with MS detection (FAC-MS) in drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Protein-doped monolithic silica columns for capillary liquid chromatography prepared by the sol-gel method: applications to frontal affinity chromatography.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Capillary-scale frontal affinity chromatography/MALDI tandem mass spectrometry using protein-doped monolithic silica columns.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

High-throughput screening for enzyme inhibitors using frontal affinity chromatography with liquid chromatography and mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

The evolving role of natural products in drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

Fragment-based lead discovery: leads by design

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2.6.891

21 January 2018

Identifiers

DOI

10.1586/14789450.2.6.891

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13 August 2017

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