A novel Apaf-1-independent putative caspase-2 activation complex (Q36324314)

13 August 2017

A novel Apaf-1-independent putative caspase-2 activation complex (English)

1 reference

13 August 2017

Paul G Ekert

3

0 references

David L Vaux

object named as

David L Vaux

4

0 references

Sharad Kumar

object named as

Sharad Kumar

5

0 references

author name string

Stuart H Read

1

1 reference

13 August 2017

Belinda C Baliga

2

1 reference

13 August 2017

language of work or name

English

0 references

publication date

2 December 2002

1 reference

13 August 2017

Journal of Cell Biology

1 reference

13 August 2017

159

1 reference

13 August 2017

5

1 reference

13 August 2017

739-745

1 reference

describes a project that uses

13 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2173397/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173397

Apoptosis. A cinderella caspase takes center stage

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173397

The role of cytochrome c in caspase activation in Drosophila melanogaster cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173397

Dimer formation drives the activation of the cell death protease caspase 9

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173397

Physiological concentrations of K+ inhibit cytochrome c-dependent formation of the apoptosome

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173397

Subcellular localization and CARD-dependent oligomerization of the death adaptor RAIDD.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173397

Serial killers: ordering caspase activation events in apoptosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173397

Mechanisms mediating caspase activation in cell death

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173397

Caspase structure, proteolytic substrates, and function during apoptotic cell death

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173397

An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173397

Caspase-9 can be activated without proteolytic processing

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173397

Defects in regulation of apoptosis in caspase-2-deficient mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173397

Functional activation of Nedd2/ICH-1 (caspase-2) is an early process in apoptosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173397

RAIDD is a new 'death' adaptor molecule

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173397

Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173397

Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173397

Inhibition of apoptosis by the expression of antisense Nedd2.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173397

Conversion of procaspase-3 to an autoactivating caspase by fusion to the caspase-2 prodomain

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173397

Prodomain-dependent nuclear localization of the caspase-2 (Nedd2) precursor. A novel function for a caspase prodomain

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173397

Dimerization and autoprocessing of the Nedd2 (caspase-2) precursor requires both the prodomain and the carboxyl-terminal regions

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173397

Processing of the Nedd2 precursor by ICE-like proteases and granzyme B.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173397

Isolation and characterization of mitochondria from human B lymphoblastoid cell lines

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173397

Caspase-2 acts upstream of mitochondria to promote cytochrome c release during etoposide-induced apoptosis

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173397

Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173397

Proteasome inhibitor-induced apoptosis of B-chronic lymphocytic leukaemia cells involves cytochrome c release and caspase activation, accompanied by formation of an approximately 700 kDa Apaf-1 containing apoptosome complex

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173397

Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2173397

Caspase activation involves the formation of the aposome, a large (approximately 700 kDa) caspase-activating complex

5 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12460989

12 December 2020

inferred from PubMed ID database lookup

Apaf-1 oligomerizes into biologically active approximately 700-kDa and inactive approximately 1.4-MDa apoptosome complexes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12460989

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1083/JCB.200209004

1 reference

release_uk3xhrqbi5gpdp44bge6s23cca

13 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/uk3xhrqbi5gpdp44bge6s23cca

24 November 2022

mapped directly with Wikidata item

1 reference

13 August 2017

1 reference