Oxygen versus Reactive Oxygen in the Regulation of HIF-1α: The Balance Tips (Q36326686)

13 August 2017

Oxygen versus Reactive Oxygen in the Regulation of HIF-1α: The Balance Tips (English)

1 reference

13 August 2017

Thilo Hagen

1

1 reference

13 August 2017

9 October 2012

1 reference

Biochemistry Research International

13 August 2017

1 reference

13 August 2017

2012

1 reference

13 August 2017

436981

1 reference

Creative Commons Attribution 3.0 Unported

13 August 2017

start time

1 January 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

cites work

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The FIH hydroxylase is a cellular peroxide sensor that modulates HIF transcriptional activity

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Human CHCHD4 mitochondrial proteins regulate cellular oxygen consumption rate and metabolism and provide a critical role in hypoxia signaling and tumor progression

30 September 2017

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Stabilization of hypoxia-inducible factor-1alpha protein in hypoxia occurs independently of mitochondrial reactive oxygen species production.

30 September 2017

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Hypoxia triggers subcellular compartmental redox signaling in vascular smooth muscle cells

30 September 2017

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30 September 2017

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Superoxide flashes in single mitochondria

30 September 2017

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Induction of HIF-2alpha is dependent on mitochondrial O2 consumption in an O2-sensitive adrenomedullary chromaffin cell line

30 September 2017

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3,3'-diindolylmethane reduces levels of HIF-1alpha and HIF-1 activity in hypoxic cultured human cancer cells

30 September 2017

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Mitochondrial reactive oxygen species trigger hypoxia-inducible factor-dependent extension of the replicative life span during hypoxia

30 September 2017

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The Qo site of the mitochondrial complex III is required for the transduction of hypoxic signaling via reactive oxygen species production

30 September 2017

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Multiple factors affecting cellular redox status and energy metabolism modulate hypoxia-inducible factor prolyl hydroxylase activity in vivo and in vitro

30 September 2017

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Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing

30 September 2017

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Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-alpha activation

30 September 2017

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Inhibition of mitochondrial respiration elevates oxygen concentration but leaves regulation of hypoxia-inducible factor (HIF) intact

30 September 2017

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Redistribution of intracellular oxygen in hypoxia by nitric oxide: effect on HIF1alpha

30 September 2017

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A conserved family of prolyl-4-hydroxylases that modify HIF

30 September 2017

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C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

30 September 2017

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HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

30 September 2017

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Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

30 September 2017

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Prolonged hypoxia during cell development protects mature manganese superoxide dismutase-deficient astrocytes from damage by oxidative stress

30 September 2017

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Selective targeting of a redox-active ubiquinone to mitochondria within cells: antioxidant and antiapoptotic properties

30 September 2017

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Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing

30 September 2017

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Mitochondrial reactive oxygen species trigger hypoxia-induced transcription

30 September 2017

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A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

30 September 2017

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Oxygen sensitivity of mitochondrial reactive oxygen species generation depends on metabolic conditions

30 September 2017

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Spatial patterning of metabolism by mitochondria, oxygen, and energy sinks in a model cytoplasm

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Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation

29 June 2018

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Reduced mitochondrial manganese-superoxide dismutase activity exacerbates glutamate toxicity in cultured mouse cortical neurons

21 January 2018

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Oligomycin inhibits HIF-1alpha expression in hypoxic tumor cells

21 January 2018

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Monitoring of cell oxygenation and responses to metabolic stimulation by intracellular oxygen sensing technique

21 January 2018

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Response of mitochondrial reactive oxygen species generation to steady-state oxygen tension: implications for hypoxic cell signaling

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23091723

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mitochondria: oxygen sinks rather than sensors?

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23091723

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1155/2012/436981

1 reference

13 August 2017

1 reference

PMC publication ID

3474226

13 August 2017

PubMed publication ID

23091723

1 reference

PMC publication ID

3474226