Application of strain-promoted azide-alkyne cycloaddition and tetrazine ligation to targeted Fc-drug conjugates. (Q36328501)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22988967%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

Application of strain-promoted azide-alkyne cycloaddition and tetrazine ligation to targeted Fc-drug conjugates (English)

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13 February 2020

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5

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13 February 2020

author name string

Joshua D Thomas

1

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13 February 2020

Huiting Cui

2

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13 February 2020

Patrick J North

3

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13 February 2020

Thomas Hofer

4

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13 February 2020

Terrence R Burke

6

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13 February 2020

language of work or name

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25 September 2012

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13 February 2020

published in

Bioconjugate Chemistry

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13 February 2020

volume

23

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13 February 2020

issue

10

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13 February 2020

page(s)

2007-2013

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A decade of bioorthogonal chemistry

13 February 2020

cites work

1 reference

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Biomedical applications of tetrazine cycloadditions

30 September 2017

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30 September 2017

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Antibody-drug conjugates: targeted drug delivery for cancer

30 September 2017

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Extension of the PNA world by functionalized PNA monomers eligible candidates for inverse Diels Alder Click Chemistry

30 September 2017

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Synthesis of a DOTA--biotin conjugate for radionuclide chelation via Cu-free click chemistry

30 September 2017

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30 September 2017

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Monoclonal antibodies: versatile platforms for cancer immunotherapy

30 September 2017

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Cu-free click cycloaddition reactions in chemical biology

30 September 2017

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Molecularly defined antibody conjugation through a selenocysteine interface

30 September 2017

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Receptor-Fc fusion therapeutics, traps, and MIMETIBODY technology

30 September 2017

1 reference

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Engineered protein scaffolds as next-generation antibody therapeutics.

30 September 2017

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Inverse-electron-demand Diels-Alder reaction as a highly efficient chemoselective ligation procedure: synthesis and function of a BioShuttle for temozolomide transport into prostate cancer cells

30 September 2017

1 reference

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Tetrazine ligation: fast bioconjugation based on inverse-electron-demand Diels-Alder reactivity

30 September 2017

1 reference

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An engineered selenocysteine defines a unique class of antibody derivatives

30 September 2017

1 reference

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Second-generation difluorinated cyclooctynes for copper-free click chemistry.

30 September 2017

1 reference

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Copper-free click chemistry for dynamic in vivo imaging

30 September 2017

1 reference

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Discovery and development of folic-acid-based receptor targeting for imaging and therapy of cancer and inflammatory diseases.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3474869

A strain-promoted [3 + 2] azide-alkyne cycloaddition for covalent modification of biomolecules in living systems

30 September 2017

1 reference

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A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes

30 September 2017

1 reference

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Synthesis and in vitro evaluation of novel morpholinyl- and methylpiperazinylacyloxyalkyl prodrugs of 2-(6-methoxy-2-naphthyl)propionic acid (Naproxen) for topical drug delivery

30 September 2017

1 reference

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Application of a trifunctional reactive linker for the construction of antibody-drug hybrid conjugates

30 September 2017

1 reference

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Strain-promoted alkyne azide cycloaddition for the functionalization of poly(amide)-based dendrons and dendrimers.

29 June 2018

1 reference

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Surpassing the use of copper in the click functionalization of polymeric nanostructures: a strain-promoted approach.

22 September 2018

1 reference

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Testosteronyl-4-dimethylaminobutyrate-HCl: a prodrug with improved skin penetration rate

22 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22988967

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Toxic antibodies blitz tumours

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22988967

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/BC300052U

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22988967%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

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13 February 2020

PubMed publication ID

22988967

1 reference