Sinularin from indigenous soft coral attenuates nociceptive responses and spinal neuroinflammation in carrageenan-induced inflammatory rat model (Q36329843)

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English	Sinularin from indigenous soft coral attenuates nociceptive responses and spinal neuroinflammation in carrageenan-induced inflammatory rat model	scientific article

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scholarly article

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Europe PubMed Central

PMC publication ID

13 August 2017

Sinularin from indigenous soft coral attenuates nociceptive responses and spinal neuroinflammation in carrageenan-induced inflammatory rat model (English)

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Europe PubMed Central

PMC publication ID

13 August 2017

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author name string

Shi-Ying Huang

1

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13 August 2017

Nan-Fu Chen

2

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13 August 2017

Wu-Fu Chen

3

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13 August 2017

Han-Chun Hung

4

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13 August 2017

Hsin-Pai Lee

5

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13 August 2017

Yen-You Lin

6

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13 August 2017

Hui-Min Wang

7

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13 August 2017

Ping-Jyun Sung

8

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13 August 2017

Jyh-Horng Sheu

9

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13 August 2017

Zhi-Hong Wen

10

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13 August 2017

publication date

24 August 2012

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13 August 2017

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13 August 2017

10

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Europe PubMed Central

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13 August 2017

9

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Europe PubMed Central

PMC publication ID

13 August 2017

1899-1919

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Europe PubMed Central

PMC publication ID

13 August 2017

copyright license

Creative Commons Attribution 4.0 International

24 August 2012

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April 2022 Public Data File from Crossref

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Bioactive eunicellin-based diterpenoids from the soft coral Cladiella krempfi

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475263

30 September 2017

Bioactive cembrane-based diterpenoids from the soft coral Sinularia triangular

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475263

30 September 2017

Transforming growth factor-β1 suppression of endotoxin-induced heme oxygenase-1 in macrophages involves activation of Smad2 and downregulation of Ets-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475263

30 September 2017

Spinal phosphinositide 3-kinase-Akt-mammalian target of rapamycin signaling cascades in inflammation-induced hyperalgesia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475263

30 September 2017

Inflammatory pain signals an increase in functional expression of organic anion transporting polypeptide 1a4 at the blood-brain barrier

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30 September 2017

Oxygenated cembranoids from the cultured and wild-type soft corals Sinularia flexibilis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475263

30 September 2017

Capnellene, a natural marine compound derived from soft coral, attenuates chronic constriction injury-induced neuropathic pain in rats

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475263

30 September 2017

Neuropathic pain: a maladaptive response of the nervous system to damage

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30 September 2017

Transforming growth factor-beta signaling alters substrate permeability and tight junction protein expression at the blood-brain barrier during inflammatory pain

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30 September 2017

Pathological and protective roles of glia in chronic pain

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30 September 2017

Inducible nitric oxide synthase and cyclooxygenase-2 participate in anti-inflammatory and analgesic effects of the natural marine compound lemnalol from Formosan soft coral Lemnalia cervicorni.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475263

30 September 2017

Antiinflammatory and antinociceptive effects of the selective histamine H4-receptor antagonists JNJ7777120 and VUF6002 in a rat model of carrageenan-induced acute inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475263

30 September 2017

The role of neuroinflammation in neuropathic pain: mechanisms and therapeutic targets

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475263

30 September 2017

Leukocytes in the regulation of pain and analgesia

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30 September 2017

Role of the immune system in chronic pain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475263

30 September 2017

Protein measurement with the Folin phenol reagent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475263

30 September 2017

Transforming growth factor-beta 1 inhibition of macrophage activation is mediated via Smad3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475263

30 September 2017

Role of oxygen radicals and arachidonic acid metabolites in the reverse passive Arthus reaction and carrageenin paw oedema in the rat

1 reference

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30 September 2017

Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain

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30 September 2017

Quantitative assessment of tactile allodynia in the rat paw

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475263

30 September 2017

A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475263

30 September 2017

Protective effect of transforming growth factor beta 1 on experimental autoimmune diseases in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475263

30 September 2017

Staining of glial fibrillary acidic protein (GFAP) in lumbar spinal cord increases following a sciatic nerve constriction injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475263

30 September 2017

Dissociation of microglial activation and neuropathic pain behaviors following peripheral nerve injury in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475263

29 June 2018

Nitric oxide: a key mediator in the early and late phase of carrageenan-induced rat paw inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475263

29 June 2018

The anti-inflammatory activity of marine natural products--6-n-tridecylsalicylic acid, flexibilide and dendalone 3-hydroxybutyrate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475263

29 June 2018

Variability of terpene content in the soft coralSinularia flexibilis (Coelenterata: Octocorallia), and its ecological implications.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475263

22 September 2018

Glucosamine sulfate reduces experimental osteoarthritis and nociception in rats: association with changes of mitogen-activated protein kinase in chondrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475263

22 September 2018

Chronic restraint stress induces mechanical and cold allodynia, and enhances inflammatory pain in rat: Relevance to human stress-associated painful pathologies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475263

22 September 2018

TGF-beta 1 protects against Abeta-neurotoxicity via the phosphatidylinositol-3-kinase pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475263

22 September 2018

Crucial role of neutrophils in the development of mechanical inflammatory hypernociception

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475263

22 September 2018

Minocycline attenuates mechanical allodynia and proinflammatory cytokine expression in rat models of pain facilitation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475263

22 September 2018

The potent inducible nitric oxide synthase inhibitor ONO-1714 inhibits neuronal NOS and exerts antinociception in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475263

22 September 2018

Ethosuximide reverses paclitaxel- and vincristine-induced painful peripheral neuropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475263

22 September 2018

Sodium iodoacetate-induced experimental osteoarthritis and associated pain model in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475263

22 September 2018

Intact carrageenan-induced thermal hyperalgesia in mice lacking inducible nitric oxide synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475263

22 September 2018

Propentofylline, a glial modulating agent, exhibits antiallodynic properties in a rat model of neuropathic pain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475263

22 September 2018

Neuropathic pain in aged rats: behavioral responses and astrocytic activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475263

22 September 2018

Partial peripheral nerve injury leads to activation of astroglia and microglia which parallels the development of allodynic behavior.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3475263

22 September 2018

Sampling and analysis of cerebrospinal fluid for chronic studies in awake rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/23118711

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A neuroprotective sulfone of marine origin and the in vivo anti-inflammatory activity of an analogue

1 reference

https://pubmed.ncbi.nlm.nih.gov/23118711

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TGF-beta inhibits lipopolysaccharide-stimulated activity of c-Jun N-terminal kinase in mouse macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/23118711

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of site and type of nerve injury on spinal glial activation and neuropathic pain behavior

1 reference

https://pubmed.ncbi.nlm.nih.gov/23118711

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglial proliferation in the spinal cord of aged rats with a sciatic nerve injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/23118711

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carrageenin-induced edema in hind paw of the rat as an assay for antiiflammatory drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/23118711

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute Intracerebroventricular Administration of Palmitoylethanolamide, an Endogenous Peroxisome Proliferator-Activated Receptor- Agonist, Modulates Carrageenan-Induced Paw Edema in Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23118711

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiac and vascular responses of isolated rat tissues treated with diterpenes from Sinularia flexibilis (coelenterata: octocorallia)

1 reference

https://pubmed.ncbi.nlm.nih.gov/23118711

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antimicrobial activity of the diterpenes flexibilide and sinulariolide derived from Sinularia flexibilis Quoy and Gaimard 1833 (Coelenterata: Alcyonacea, Octocorallia)

1 reference

https://pubmed.ncbi.nlm.nih.gov/23118711

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intrathecal lemnalol, a natural marine compound obtained from Formosan soft coral, attenuates nociceptive responses and the activity of spinal glial cells in neuropathic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/23118711

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The analgesic, anti-inflammatory and calcium antagonist potential of Tanacetum artemisioides

1 reference

https://pubmed.ncbi.nlm.nih.gov/23118711

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3390/MD10091899

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

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