Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis (Q36338892)

13 August 2017

Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis (English)

1 reference

13 August 2017

0 references

12

1 reference

13 August 2017

Alexander Gusev

3

0 references

Sang Hong Lee

object named as

Sang Hong Lee

9

0 references

Naomi R. Wray

object named as

Naomi R Wray

10

0 references

Kenneth Kendler

11

object named as

Kenneth S Kendler

1 reference

13 August 2017

0 references

14

Nick Patterson

1 reference

13 August 2017

13

Benjamin M Neale

1 reference

13 August 2017

Po-Ru Loh

1

1 reference

13 August 2017

Gaurav Bhatia

2

1 reference

13 August 2017

Hilary K Finucane

4

1 reference

13 August 2017

Brendan K Bulik-Sullivan

5

1 reference

13 August 2017

Samuela J Pollack

6

1 reference

13 August 2017

Schizophrenia Working Group of Psychiatric Genomics Consortium

7

1 reference

13 August 2017

Teresa R de Candia

8

1 reference

13 August 2017

Alkes L Price

15

1 reference

13 August 2017

language of work or name

English

0 references

publication date

2 November 2015

1 reference

13 August 2017

1 reference

13 August 2017

47

1 reference

13 August 2017

12

1 reference

13 August 2017

1385-1392

1 reference

Partitioning heritability by functional annotation using genome-wide association summary statistics

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

An atlas of genetic correlations across human diseases and traits

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Second-generation PLINK: rising to the challenge of larger and richer datasets

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Genetic studies of body mass index yield new insights for obesity biology

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Efficient Bayesian mixed-model analysis increases association power in large cohorts.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Adjusting for heritable covariates can bias effect estimates in genome-wide association studies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Biological interpretation of genome-wide association studies using predicted gene functions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Measuring missing heritability: inferring the contribution of common variants

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

A general unified framework to assess the sampling variance of heritability estimates using pedigree or marker-based relationships

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Defining the role of common variation in the genomic and biological architecture of adult human height

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Methylation QTLs are associated with coordinated changes in transcription factor binding, histone modifications, and gene expression levels

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Biological insights from 108 schizophrenia-associated genetic loci

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

The impact of population demography and selection on the genetic architecture of complex traits

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Statistical power to detect genetic (co)variance of complex traits using SNP data in unrelated samples.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Advantages and pitfalls in the application of mixed-model association methods

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Searching for missing heritability: designing rare variant association studies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Quantifying missing heritability at known GWAS loci

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Employing a Monte Carlo algorithm in Newton-type methods for restricted maximum likelihood estimation of genetic parameters

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Discovery and refinement of loci associated with lipid levels

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Improving the accuracy and efficiency of partitioning heritability into the contributions of genomic regions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Improved ancestry inference using weights from external reference panels

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

DNA-methylation effect on cotranscriptional splicing is dependent on GC architecture of the exon-intron structure

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Polygenic modeling with bayesian sparse linear mixed models

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Improved heritability estimation from genome-wide SNPs

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Differential relationship of DNA replication timing to different forms of human mutation and variation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Estimation of pleiotropy between complex diseases using single-nucleotide polymorphism-derived genomic relationships and restricted maximum likelihood

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Population structure of Hispanics in the United States: the multi-ethnic study of atherosclerosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Heritability and genetic correlations explained by common SNPs for metabolic syndrome traits

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Rare and common variants: twenty arguments

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Genome-wide association study identifies five new schizophrenia loci

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Identification of IL6R and chromosome 11q13.5 as risk loci for asthma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Next generation genome-wide association tool: design and coverage of a high-throughput European-optimized SNP array

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Genome partitioning of genetic variation for complex traits using common SNPs

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Estimating missing heritability for disease from genome-wide association studies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

GCTA: a tool for genome-wide complex trait analysis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Robust relationship inference in genome-wide association studies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Common SNPs explain a large proportion of the heritability for human height

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Widespread genomic signatures of natural selection in hominid evolution

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Common genetic variation and human traits

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

A second generation human haplotype map of over 3.1 million SNPs

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

A polygenic theory of schizophrenia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Estimation of SNP heritability from dense genotype data

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Puzzling over schizophrenia: schizophrenia as a pathway disease

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Efficient methods to compute genomic predictions

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Technical note: Computing strategies in genome-wide selection.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666835

Recovery of inter-block information when block sizes are unequal

22 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNG.3431

Computational neuroanatomy of speech production.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNG.3431

A COMPARISON OF GENETIC AND PHENOTYPIC CORRELATIONS.

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26523775

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The investigation of linkage between a quantitative trait and a marker locus

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26523775

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Linking the SWI/SNF complex to prostate cancer.

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNG.3431

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NG.3431

1 reference

13 August 2017

1 reference

13 August 2017

PubMed publication ID

26523775

1 reference