Human cyt P450 mediated metabolic toxicity of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) evaluated using electrochemiluminescent arrays (Q36347374)

From Wikidata

Jump to navigation Jump to search

scientific article

Language	Label	Description	Also known as
English	Human cyt P450 mediated metabolic toxicity of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) evaluated using electrochemiluminescent arrays	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Human cyt P450 mediated metabolic toxicity of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) evaluated using electrochemiluminescent arrays (English)

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

John B. Schenkman

4

object named as

John B Schenkman

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

James F. Rusling

5

object named as

James F Rusling

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

author name string

Sadagopan Krishnan

1

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Eli G Hvastkovs

2

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Besnik Bajrami

3

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

publication date

12 December 2008

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

number of pages

7

1 reference

based on heuristic

inferred from page(s)

Molecular BioSystems

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

5

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

2

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

163-169

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Synergistic metabolic toxicity screening using microsome/DNA electrochemiluminescent arrays and nanoreactors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

30 September 2017

Meat and meat mutagens and risk of prostate cancer in the Agricultural Health Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

30 September 2017

Biochemical applications of ultrathin films of enzymes, polyions and DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

30 September 2017

Cytochrome p450 and chemical toxicology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

30 September 2017

Occurrence, genotoxicity, and carcinogenicity of regulated and emerging disinfection by-products in drinking water: a review and roadmap for research

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

30 September 2017

The application of discovery toxicology and pathology towards the design of safer pharmaceutical lead candidates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

30 September 2017

Toxicity screening using biosensors that measure DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

30 September 2017

Electrochemiluminescent arrays for cytochrome P450-activated genotoxicity screening. DNA damage from benzo[a]pyrene metabolites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

30 September 2017

Xenobiotic-metabolizing enzymes in human lung

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

30 September 2017

Cytochrome P450s and other enzymes in drug metabolism and toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

30 September 2017

Cytochrome P450 expression and metabolic activation of cooked food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in MCF10A breast epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

30 September 2017

Measuring DNA nucleobase adducts using neutral hydrolysis and liquid chromatography-mass spectrometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

30 September 2017

Genotoxicity of heat-processed foods

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

30 September 2017

Elucidating mechanisms of drug-induced toxicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

30 September 2017

Genotoxicity of tobacco smoke and tobacco smoke condensate: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

30 September 2017

The genotoxicity of ambient outdoor air, a review: Salmonella mutagenicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

30 September 2017

Mutagens in surface waters: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

30 September 2017

Idiosyncratic toxicity: the role of toxicophores and bioactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

30 September 2017

Tobacco carcinogens, their biomarkers and tobacco-induced cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

30 September 2017

THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. II. SOLUBILIZATION, PURIFICATION, AND PROPERTIES

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

30 September 2017

Tobacco smoke carcinogens, DNA damage and p53 mutations in smoking-associated cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

30 September 2017

Human cytochrome P450 CYP2A13: predominant expression in the respiratory tract and its high efficiency metabolic activation of a tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

30 September 2017

Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

30 September 2017

Kinetic analysis of the activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by heterologously expressed human P450 enzymes and the effect of P450-specific chemical inhibitors on this activation in human liver microsomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

30 September 2017

Controlling the avoidable causes of cancer: needs and opportunities for etiologic research

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

30 September 2017

Benzo[alpha]pyrene metabolism, activation and carcinogenesis: role and regulation of mixed-function oxidases and related enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

30 September 2017

Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons: G. H. A. Clowes Memorial Lecture.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

30 September 2017

Tobacco-specific nitrosamines, an important group of carcinogens in tobacco and tobacco smoke.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

30 September 2017

Endogenous mutagens and the causes of aging and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

30 September 2017

High-level expression of functional human cytochrome P450 1A2 in Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

30 September 2017

The mechanism of action of cytochrome P-450. Occurrence of the 'NIH shift' during hydroperoxide-dependent aromatic hydroxylations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

30 September 2017

Cytochrome P-4502E1: its physiological and pathological role

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

30 September 2017

Targeting of lung cancer mutational hotspots by polycyclic aromatic hydrocarbons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

29 June 2018

Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by human cytochrome P450 1A2 and its inhibition by phenethyl isothiocyanate.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

29 June 2018

Matabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by cytochrome P450IIB1 in a reconstituted system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

29 June 2018

A comparative study of pH/activity profiles for the anaerobic H2O2 and alkyl hydroperoxide supported N demethylation of N methylaniline catalyzed by alkaline haematin and microsomal cytochrome P-450

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

29 June 2018

Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by inducible and constitutive cytochrome P450 enzymes in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

29 June 2018

Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

29 June 2018

Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in human lung and liver microsomes and cytochromes P-450 expressed in hepatoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

29 June 2018

Simultaneous direct electrochemiluminescence and catalytic voltammetry detection of DNA in ultrathin films.

1 reference

https://api.crossref.org/works/10.1039%2FB815910F

21 January 2018

Toxicity screening by electrochemical detection of DNA damage by metabolites generated in situ in ultrathin DNA-enzyme films

1 reference

https://api.crossref.org/works/10.1039%2FB815910F

21 January 2018

Evaluating enzymes that generate genotoxic benzo[a]pyrene metabolites using sensor arrays

1 reference

https://api.crossref.org/works/10.1039%2FB815910F

21 January 2018

Enzyme-DNA biocolloids for DNA adduct and reactive metabolite detection by chromatography-mass spectrometry

1 reference

https://api.crossref.org/works/10.1039%2FB815910F

21 January 2018

Quantitative measurement of DNA adducts using neutral hydrolysis and LC-MS. Validation of genotoxicity sensors

1 reference

https://api.crossref.org/works/10.1039%2FB815910F

21 January 2018

Covalent DNA adducts formed in mouse epidermis by benzo[g]chrysene.

1 reference

https://api.crossref.org/works/10.1039%2FB815910F

21 January 2018

Characterization of xenobiotic-metabolizing enzymes and nitrosamine metabolism in the human esophagus.

1 reference

https://api.crossref.org/works/10.1039%2FB815910F

21 January 2018

Biochemistry, biology, and carcinogenicity of tobacco-specific N-nitrosamines

1 reference

https://api.crossref.org/works/10.1039%2FB815910F

21 January 2018

Expression of modified human cytochrome P450 2E1 in Escherichia coli, purification, and spectral and catalytic properties.

1 reference

https://api.crossref.org/works/10.1039%2FB815910F

21 January 2018

Effect of surface immobilization on the electrochemiluminescence of ruthenium-containing metallopolymers

1 reference

https://api.crossref.org/works/10.1039%2FB815910F

21 January 2018

Metabolism of benzo[a]pyrene to trans-7,8-dihydroxy-7, 8-dihydrobenzo[a]pyrene by recombinant human cytochrome P450 1B1 and purified liver epoxide hydrolase.

1 reference

https://api.crossref.org/works/10.1039%2FB815910F

21 January 2018

Identification of adducts formed by pyridyloxobutylation of deoxyguanosine and DNA by 4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone, a chemically activated form of tobacco specific carcinogens

1 reference

https://api.crossref.org/works/10.1039%2FB815910F

21 January 2018

Transplacental induction of pancreas tumors in hamsters by ethanol and the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

22 September 2018

A colorimetric assay for immobilized chloroperoxidase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481181

22 September 2018

A guide to drug discovery: The role of the medicinal chemist in drug discovery — then and now

1 reference

https://api.crossref.org/works/10.1039%2FB815910F

21 January 2018

The sources and potential hazards of mutagens in complex environmental matrices

1 reference

https://api.crossref.org/works/10.1039%2FB815910F

21 January 2018

Evidence for a homolytic mechanism of peroxide oxygen--oxygen bond cleavage during substrate hydroxylation by cytochrome P-450

1 reference

https://pubmed.ncbi.nlm.nih.gov/19156262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low levels of expression of cytochromes P-450 in normal and cancerous fetal pancreatic tissues of hamsters treated with NNK and/or ethanol

1 reference

https://pubmed.ncbi.nlm.nih.gov/19156262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mouse lung microsomes and its inhibition by isothiocyanates

1 reference

https://pubmed.ncbi.nlm.nih.gov/19156262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic Polymorphisms in Xenobiotic Clearance Genes and Their Influence on Disease Expression in Hereditary Nonpolyposis Colorectal Cancer Patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19156262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of benzo[a]pyrene to DNA by cytochrome P-450 catalyzed one-electron oxidation in rat liver microsomes and nuclei

1 reference

https://pubmed.ncbi.nlm.nih.gov/19156262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced expression of CYP1B1 in Escherichia coli

1 reference

https://pubmed.ncbi.nlm.nih.gov/19156262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and quantitation of benzo[a]pyrene-DNA adducts formed in mouse skin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19156262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heterocyclic amine content of cooked meat and risk of prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19156262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interindividual variability in the expression and NNK carbonyl reductase activity of 11beta-hydroxysteroid dehydrogenase 1 in human lung

1 reference

https://pubmed.ncbi.nlm.nih.gov/19156262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genotoxicity screening for N-nitroso compounds. Electrochemical and electrochemiluminescent detection of human enzyme-generated DNA damage from N-nitrosopyrrolidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19156262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sex differences in lung CYP1A1 expression and DNA adduct levels among lung cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19156262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1039/B815910F

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

release_m4yjqnai5feyrih3mmjwd2rx2q

1 reference

https://api.fatcat.wiki/v0/release/m4yjqnai5feyrih3mmjwd2rx2q

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q36347374&oldid=2243777992"