CRASH-3 - tranexamic acid for the treatment of significant traumatic brain injury: study protocol for an international randomized, double-blind, placebo-controlled trial (Q36347953)

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scientific article published on 21 June 2012

Language	Label	Description	Also known as
English	CRASH-3 - tranexamic acid for the treatment of significant traumatic brain injury: study protocol for an international randomized, double-blind, placebo-controlled trial	scientific article published on 21 June 2012

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scholarly article

1 reference

Europe PubMed Central

13 August 2017

CRASH-3 - tranexamic acid for the treatment of significant traumatic brain injury: study protocol for an international randomized, double-blind, placebo-controlled trial (English)

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Europe PubMed Central

13 August 2017

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traumatic brain injury

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placebo-controlled trial

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based on heuristic

inferred from title

tranexamic acid

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based on heuristic

inferred from title

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based on heuristic

inferred from title

Haleema Shakur-Still

object named as

Haleema Shakur

6

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4

object named as

Pablo Perel

1 reference

Europe PubMed Central

13 August 2017

5

object named as

Ian Roberts

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Europe PubMed Central

13 August 2017

1

object named as

Yashbir Dewan

1 reference

Europe PubMed Central

13 August 2017

Edward O Komolafe

2

object named as

Edward O Komolafe

1 reference

Europe PubMed Central

13 August 2017

Jorge H Mejía-Mantilla

3

object named as

Jorge H Mejía-Mantilla

1 reference

Europe PubMed Central

13 August 2017

author name string

CRASH-3 Collaborators

7

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Europe PubMed Central

13 August 2017

publication date

21 June 2012

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Europe PubMed Central

13 August 2017

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Europe PubMed Central

13 August 2017

13

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Europe PubMed Central

13 August 2017

87

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Europe PubMed Central

13 August 2017

https://scigraph.springernature.com/pub.10.1186/1745-6215-13-87

0 references

Effect of tranexamic acid in traumatic brain injury: a nested randomised, placebo controlled trial (CRASH-2 Intracranial Bleeding Study).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481366

30 September 2017

Cost-effectiveness analysis of administering tranexamic acid to bleeding trauma patients using evidence from the CRASH-2 trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481366

30 September 2017

The importance of early treatment with tranexamic acid in bleeding trauma patients: An exploratory analysis of the CRASH-2 randomised controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481366

30 September 2017

Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481366

30 September 2017

Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481366

30 September 2017

Intracranial bleeding in patients with traumatic brain injury: a prognostic study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481366

30 September 2017

Coagulation disorders after traumatic brain injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481366

30 September 2017

Final results of MRC CRASH, a randomised placebo-controlled trial of intravenous corticosteroid in adults with head injury-outcomes at 6 months

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481366

30 September 2017

The Epidemiology of Traumatic Brain Injury: A Review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481366

30 September 2017

Equipoise and the ethics of clinical research

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481366

30 September 2017

Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. analysis and examples

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481366

30 September 2017

For and against: clinical equipoise and not the uncertainty principle is the moral underpinning of the randomised controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481366

29 June 2018

Trials: the next 50 years. Large scale randomised evidence of moderate benefits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481366

29 June 2018

Effect of consent rituals on mortality in emergency care research

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481366

22 September 2018

Progression of traumatic intracerebral hemorrhage: a prospective observational study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481366

22 September 2018

Fibrinolytic markers and neurologic outcome in traumatic brain injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481366

22 September 2018

The role of endogenous versus exogenous tPA on edema formation in murine ICH.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481366

22 September 2018

The long-term effect of recombinant tissue-plasminogen-activator (rt-PA) on edema formation in a large-animal model of intracerebral hemorrhage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481366

22 September 2018

Relative edema volume is a predictor of outcome in patients with hyperacute spontaneous intracerebral hemorrhage.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481366

22 September 2018

Progressive hemorrhage after head trauma: predictors and consequences of the evolving injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481366

22 September 2018

Plasminogen activators potentiate thrombin-induced brain injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481366

22 September 2018

Disability rating scale for severe head trauma: coma to community.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481366

22 September 2018

Repeated assessment of results in clinical trials of cancer treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/22721545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The dose-response relationship of tranexamic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/22721545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1745-6215-13-87

1 reference

Europe PubMed Central

13 August 2017

release_4n6fe3yoyjasfbore6dnro6hae

1 reference

https://api.fatcat.wiki/v0/release/4n6fe3yoyjasfbore6dnro6hae

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

ResearchGate publication ID

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