Role of astrocytes in glutamate homeostasis: implications for excitotoxicity (Q36349887)

13 August 2017

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title

Role of astrocytes in glutamate homeostasis: implications for excitotoxicity (English)

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13 August 2017

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Arne Schousboe

1

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PubMed ID

16371316

13 August 2017

Helle S Waagepetersen

series ordinal

2

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13 August 2017

1 November 2005

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13 August 2017

Neurotoxicity Research

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13 August 2017

8

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13 August 2017

3-4

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13 August 2017

221-225

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https://scigraph.springernature.com/pub.10.1007/bf03033975

13 August 2017

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Reduced postischemic expression of a glial glutamate transporter, GLT1, in the rat hippocampus

21 January 2018

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Analysis of glutamine accumulation in rat brain mitochondria in the presence of a glutamine uptake inhibitor, histidine, reveals glutamine pools with a distinct access to deamidation

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Differential expressions of glycine transporter 1 and three glutamate transporter mRNA in the hippocampus of gerbils with transient forebrain ischemia.

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Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate

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Multiple compartments with different metabolic characteristics are involved in biosynthesis of intracellular and released glutamine and citrate in astrocytes

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Metabolism and role of glutamate in mammalian brain

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Cellular distribution and kinetic properties of high-affinity glutamate transporters

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Fine structural localization of glutamine synthetase in astrocytes of rat brain

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The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death

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Astrocytes: glutamate producers for neurons

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Kinetic characteristics of the glutamate uptake into normal astrocytes in cultures

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Kinetics and localization of brain phosphate activated glutaminase

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GDNF and neublastin protect against NMDA-induced excitotoxicity in hippocampal slice cultures

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Glutamate release in severe brain ischaemia is mainly by reversed uptake.

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An energy budget for signaling in the grey matter of the brain

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Elevation of the Extracellular Concentrations of Glutamate and Aspartate in Rat Hippocampus During Transient Cerebral Ischemia Monitored by Intracerebral Microdialysis

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Impairment of glutamate transport and increased vulnerability to oxidative stress in neuroblastoma SH-SY5Y cells expressing a Cu,Zn superoxide dismutase typical of familial amyotrophic lateral sclerosis.

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Demonstration of pyruvate recycling in primary cultures of neocortical astrocytes but not in neurons

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Differential expression of glutamate dehydrogenase in cultured neurons and astrocytes from mouse cerebellum and cerebral cortex

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Traumatic brain injury down-regulates glial glutamate transporter (GLT-1 and GLAST) proteins in rat brain.

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The release and uptake of excitatory amino acids

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Glial glutamate transporter GLT-1 down-regulation precedes delayed neuronal death in gerbil hippocampus following transient global cerebral ischemia

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Evidence that aspartate aminotransferase activity and ketodicarboxylate carrier function are essential for biosynthesis of transmitter glutamate

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Extracellular overflow of neuroactive amino acids during severe insulin-induced hypoglycemia: in vivo dialysis of the rat hippocampus.

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Identifiers

DOI

10.1007/BF03033975

1 reference

13 August 2017

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PubMed ID

16371316