Negative regulation of p120GAP GTPase promoting activity by p210bcr/abl: implication for RAS-dependent Philadelphia chromosome positive cell growth (Q36363202)

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English	Negative regulation of p120GAP GTPase promoting activity by p210bcr/abl: implication for RAS-dependent Philadelphia chromosome positive cell growth	scientific article

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scholarly article

1 reference

Europe PubMed Central

13 August 2017

Negative regulation of p120GAP GTPase promoting activity by p210bcr/abl: implication for RAS-dependent Philadelphia chromosome positive cell growth (English)

1 reference

Europe PubMed Central

13 August 2017

1 reference

based on heuristic

inferred from title

author name string

T Skorski

1

1 reference

Europe PubMed Central

13 August 2017

P Kanakaraj

2

1 reference

Europe PubMed Central

13 August 2017

D H Ku

3

1 reference

Europe PubMed Central

13 August 2017

M Nieborowska-Skorska

4

1 reference

Europe PubMed Central

13 August 2017

E Canaani

5

1 reference

Europe PubMed Central

13 August 2017

G Zon

6

1 reference

Europe PubMed Central

13 August 2017

B Perussia

7

1 reference

Europe PubMed Central

13 August 2017

B Calabretta

8

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Europe PubMed Central

13 August 2017

language of work or name

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publication date

1 June 1994

1 reference

Europe PubMed Central

13 August 2017

Journal of Experimental Medicine

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Europe PubMed Central

13 August 2017

179

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Europe PubMed Central

13 August 2017

6

1 reference

Europe PubMed Central

13 August 2017

1855-1865

1 reference

Europe PubMed Central

13 August 2017

Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor

1 reference

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BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein

1 reference

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Antigen-induced B lymphocyte activation involves the p21ras and ras.GAP signaling pathway.

1 reference

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Increased levels of p21ras-GTP and enhanced DNA synthesis accompany elevated tyrosyl phosphorylation of GAP-associated proteins, p190 and p62, in c-src overexpressors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191514

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Identification of the SH3 domain of GAP as an essential sequence for Ras-GAP-mediated signaling

1 reference

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Gene Transfer: DNA Microinjection Compared with DNA Transfection with a Very High Efficiency

1 reference

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DNA-mediated gene transfer without carrier DNA

1 reference

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SV40-transformed simian cells support the replication of early SV40 mutants

1 reference

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Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells

1 reference

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Human c-myb protooncogene: nucleotide sequence of cDNA and organization of the genomic locus

1 reference

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In vitro transformation of immature hematopoietic cells by the P210 BCR/ABL oncogene product of the Philadelphia chromosome

1 reference

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30 September 2017

The c-K-ras gene and human cancer (review)

1 reference

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RAS gene mutations in acute and chronic myelocytic leukemias, chronic myeloproliferative disorders, and myelodysplastic syndromes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191514

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Alternative splicing of RNAs transcribed from the human abl gene and from the bcr-abl fused gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191514

30 September 2017

Human N-ras: cDNA cloning and gene structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191514

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Constitutive expression of a c-myb cDNA blocks Friend murine erythroleukemia cell differentiation

1 reference

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30 September 2017

A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191514

30 September 2017

Modulation of ras expression by anti-sense, nonionic deoxyoligonucleotide analogs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191514

30 September 2017

A C-terminal domain of GAP is sufficient to stimulate ras p21 GTPase activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191514

30 September 2017

Src homology region 2 domains direct protein-protein interactions in signal transduction

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191514

30 September 2017

Induction of a chronic myelogenous leukemia-like syndrome in mice with v-abl and BCR/ABL.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191514

30 September 2017

ras and GAP--who's controlling whom?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191514

30 September 2017

Modulation of guanine nucleotides bound to Ras in NIH3T3 cells by oncogenes, growth factors, and the GTPase activating protein (GAP)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191514

30 September 2017

The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191514

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The GAP-related domain of the neurofibromatosis type 1 gene product interacts with ras p21

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191514

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Molecular genetic advances in chronic myelogenous leukemia

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191514

30 September 2017

Protein-tyrosine kinases regulate the phosphorylation, protein interactions, subcellular distribution, and activity of p21ras GTPase-activating protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191514

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Selective Inhibition of Leukemia Cell Proliferation by BCR-ABL Antisense Oligodeoxynucleotides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191514

30 September 2017

BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191514

30 September 2017

Activation of tyrosinase kinase and microfilament-binding functions of c-abl by bcr sequences in bcr/abl fusion proteins

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191514

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bcr-abl, the hallmark of chronic myeloid leukaemia in man, induces multiple haemopoietic neoplasms in mice.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191514

30 September 2017

Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191514

30 September 2017

Regulators and Effectors of ras Proteins

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191514

30 September 2017

Regulatory mechanisms for ras proteins

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191514

30 September 2017

Molecular cloning of cDNAs encoding the GAP-associated protein p190: implications for a signaling pathway from ras to the nucleus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191514

30 September 2017

A limited set of SH2 domains binds BCR through a high-affinity phosphotyrosine-independent interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191514

30 September 2017

Molecular cloning and nucleic acid binding properties of the GAP-associated tyrosine phosphoprotein p62

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191514

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The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191514

30 September 2017

GTPase-activating protein SH2-SH3 domains induce gene expression in a Ras-dependent fashion

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191514

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Continuous growth and differentiation of human myeloid leukaemic cells in suspension culture

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30 September 2017

p120 GAP requirement in normal and malignant human hematopoiesis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191514

28 June 2018

Tyrosine phosphorylation and association with phospholipase C gamma-1 of the GAP-associated 62-kD protein after CD2 stimulation of Jurkat T cell

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191514

28 June 2018

Establishment of a Ph1-positive human cell line (BV173).

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191514

28 June 2018

Expression of a distinctive BCR-ABL oncogene in Ph1-positive acute lymphocytic leukemia (ALL).

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28 June 2018

Requirement for c-ras proteins during viral oncogene transformation

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28 June 2018

Guanosine triphosphatase activating protein (GAP) interacts with the p21 ras effector binding domain

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28 June 2018

PDGF induction of tyrosine phosphorylation of GTPase activating protein

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28 June 2018

Tyrosine kinase activity and transformation potency of bcr-abl oncogene products.

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28 June 2018

Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191514

28 June 2018

BCR-ABL and BCR proteins: biochemical characterization and localization

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28 June 2018

The pattern of mutational involvement of RAS genes in human hematologic malignancies determined by DNA amplification and direct sequencing

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28 June 2018

Acute leukaemia in bcr/abl transgenic mice

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28 June 2018

NB4, a maturation inducible cell line with t(15;17) marker isolated from a human acute promyelocytic leukemia (M3).

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28 June 2018

Differential regulation of rasGAP and neurofibromatosis gene product activities

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28 June 2018

Nerve growth factor stimulation of the Ras-guanine nucleotide exchange factor and GAP activities

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28 June 2018

Association between GTPase activators for Rho and Ras families.

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28 June 2018

Growth factor-dependent inhibition of normal hematopoiesis by N-ras antisense oligodeoxynucleotides

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28 June 2018

Stimulation of p21 ras upon T-cell activation

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Tyrosine phosphorylation of rasGAP and associated proteins in chronic myelogenous leukemia cell lines

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12 December 2020

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Initiation of deregulated growth of multipotent progenitor cells by bcr-abl in vitro

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https://pubmed.ncbi.nlm.nih.gov/8195713

12 December 2020

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Binding of the h-ras p21 GTPase activating protein by the activated epidermal growth factor receptor leads to inhibition of the p21 GTPase activity in vitro

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https://pubmed.ncbi.nlm.nih.gov/8195713

12 December 2020

based on heuristic

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Fused transcript of abl and bcr genes in chronic myelogenous leukaemia

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https://pubmed.ncbi.nlm.nih.gov/8195713

12 December 2020

based on heuristic

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Rare occurrence of N-ras point mutations in Philadelphia chromosome positive chronic myeloid leukemia

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https://pubmed.ncbi.nlm.nih.gov/8195713

12 December 2020

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P210 BCR-ABL is complexed to P160 BCR and ph-P53 proteins in K562 cells

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https://pubmed.ncbi.nlm.nih.gov/8195713

12 December 2020

based on heuristic

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Identifiers

10.1084/JEM.179.6.1855

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

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