Higher autoantibody levels and recognition of a linear NH2-terminal epitope in the autoantigen GAD65, distinguish stiff-man syndrome from insulin-dependent diabetes mellitus. (Q36363509)

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English	Higher autoantibody levels and recognition of a linear NH2-terminal epitope in the autoantigen GAD65, distinguish stiff-man syndrome from insulin-dependent diabetes mellitus.	scientific article

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20 October 2019

Higher autoantibody levels and recognition of a linear NH2-terminal epitope in the autoantigen GAD65, distinguish stiff-man syndrome from insulin-dependent diabetes mellitus (English)

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20 October 2019

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Steinunn Baekkeskov

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20 October 2019

Henry A. Erlich

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H Erlich

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20 October 2019

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J Kim

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20 October 2019

M Namchuk

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20 October 2019

T Bugawan

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20 October 2019

Q Fu

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20 October 2019

M Jaffe

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20 October 2019

Y Shi

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20 October 2019

H J Aanstoot

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20 October 2019

C W Turck

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20 October 2019

V Lennon

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1 August 1994

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20 October 2019

Journal of Experimental Medicine

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20 October 2019

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20 October 2019

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20 October 2019

595-606

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20 October 2019

Progressive fluctuating muscular rigidity and spasm ("stiff-man" syndrome); report of a case and some observations in 13 other cases.

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30 September 2017

Demonstration of GAD-65 as the main immunogenic isoform of glutamate decarboxylase in type 1 diabetes and determination of autoantibodies using a radioligand produced by eukaryotic expression

1 reference

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30 September 2017

The synaptic vesicle-associated protein amphiphysin is the 128-kD autoantigen of Stiff-Man syndrome with breast cancer

1 reference

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30 September 2017

Amino acid residues 24-31 but not palmitoylation of cysteines 30 and 45 are required for membrane anchoring of glutamic acid decarboxylase, GAD65

1 reference

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30 September 2017

Autoreactive epitopes defined by diabetes-associated human monoclonal antibodies are localized in the middle and C-terminal domains of the smaller form of glutamate decarboxylase

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191592

30 September 2017

Characterization of a linear epitope within the human pancreatic 64-kDa glutamic acid decarboxylase and its autoimmune recognition by sera from insulin-dependent diabetes mellitus patients

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191592

30 September 2017

Expression of major histocompatibility antigens on pancreatic islet cells

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30 September 2017

Antibodies to a 64,000 Mr human islet cell antigen precede the clinical onset of insulin-dependent diabetes

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30 September 2017

Stiff-man syndrome updated

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30 September 2017

Antigen uptake and accumulation in antigen-specific B cells

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30 September 2017

Monoclonal antibodies to glutamic acid decarboxylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191592

30 September 2017

Autoantibodies to GABA-ergic neurons and pancreatic beta cells in stiff-man syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191592

30 September 2017

An overview on possible mechanisms of destruction of the insulin-producing beta cell

1 reference

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30 September 2017

HLA-DR, DQ and DP typing using PCR amplification and immobilized probes

1 reference

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30 September 2017

Two genes encode distinct glutamate decarboxylases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191592

30 September 2017

Cloning, characterization, and autoimmune recognition of rat islet glutamic acid decarboxylase in insulin-dependent diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191592

30 September 2017

Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase

1 reference

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30 September 2017

Novel neuronal neurotransmitter-specific cell-surface molecules

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30 September 2017

Two human glutamate decarboxylases, 65-kDa GAD and 67-kDa GAD, are each encoded by a single gene

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30 September 2017

Membrane anchoring of the autoantigen GAD65 to microvesicles in pancreatic beta-cells by palmitoylation in the NH2-terminal domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191592

30 September 2017

Autoantibodies in IDDM primarily recognize the 65,000-M(r) rather than the 67,000-M(r) isoform of glutamic acid decarboxylase

1 reference

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28 June 2018

Identification of a dominant epitope of glutamic acid decarboxylase (GAD-65) recognized by autoantibodies in stiff-man syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191592

28 June 2018

Differential expression of GAD65 and GAD67 in human, rat, and mouse pancreatic islets.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191592

28 June 2018

Suppressive effect of antibody on processing of T cell epitopes

1 reference

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28 June 2018

Inducible expression of H-2 and Ia antigens on brain cells.

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28 June 2018

Rapid typing of HLA-DQB1 DNA polymorphism using nonradioactive oligonucleotide probes and amplified DNA.

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28 June 2018

Virus infection triggers insulin-dependent diabetes mellitus in a transgenic model: role of anti-self (virus) immune response

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28 June 2018

Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice

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28 June 2018

Studies on Autoimmunity for T-Cell-Mediated β-Cell Destruction: Distinct Difference in β-Cell Destruction Between CD4+ and CD8+ T-Cell Clones Derived From Lymphocytes Infiltrating the Islets of NOD Mice

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28 June 2018

Improved specificity of ICA assays in the Fourth International Immunology of Diabetes Serum Exchange Workshop

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28 June 2018

Recombinant glutamic acid decarboxylase (representing the single isoform expressed in human islets) detects IDDM-associated 64,000-M(r) autoantibodies.

1 reference

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28 June 2018

Characterization of the proteins purified with monoclonal antibodies to glutamic acid decarboxylase

1 reference

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22 September 2018

Pancreatic beta cells express two autoantigenic forms of glutamic acid decarboxylase, a 65-kDa hydrophilic form and a 64-kDa amphiphilic form which can be both membrane-bound and soluble

1 reference

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22 September 2018

Islet Cell and Thyrogastric Antibodies in 633 Consecutive 15- to 34-Yr-Old Patients in the Diabetes Incidence Study in Sweden

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibodies to a Mr-64000 islet cell protein in Swedish children with newly diagnosed Type 1 (insulin-dependent) diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/7519242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytoplasmic islet cell antibodies recognize distinct islet antigens in IDDM but not in stiff man syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/7519242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1084/JEM.180.2.595

1 reference

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20 October 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7519242%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

1 reference

Europe PubMed Central

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20 October 2019

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