Pharmacokinetics and pharmacodynamics of oral artesunate monotherapy in patients with uncomplicated Plasmodium falciparum malaria in western Cambodia (Q36364184)

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English	Pharmacokinetics and pharmacodynamics of oral artesunate monotherapy in patients with uncomplicated Plasmodium falciparum malaria in western Cambodia	scientific article

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scholarly article

1 reference

Europe PubMed Central

13 August 2017

Pharmacokinetics and pharmacodynamics of oral artesunate monotherapy in patients with uncomplicated Plasmodium falciparum malaria in western Cambodia (English)

1 reference

Europe PubMed Central

13 August 2017

Plasmodium falciparum

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Plasmodium falciparum malaria

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based on heuristic

inferred from title

pharmacokinetics

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based on heuristic

inferred from title

pharmacodynamics

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based on heuristic

inferred from title

Paktiya Teja-Isavadharm

18

object named as

Paktiya Teja-Isavadharm

1 reference

Europe PubMed Central

13 August 2017

13

object named as

Doung Socheat

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Europe PubMed Central

13 August 2017

author name string

David Saunders

1

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Europe PubMed Central

13 August 2017

Phisit Khemawoot

2

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Europe PubMed Central

13 August 2017

Pattaraporn Vanachayangkul

3

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Europe PubMed Central

13 August 2017

Raveewan Siripokasupkul

4

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Europe PubMed Central

13 August 2017

Delia Bethell

5

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Europe PubMed Central

13 August 2017

Stuart Tyner

6

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Europe PubMed Central

13 August 2017

Youry Se

7

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Europe PubMed Central

13 August 2017

Wiriya Rutvisuttinunt

8

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Europe PubMed Central

13 August 2017

Sabaithip Sriwichai

9

1 reference

Europe PubMed Central

13 August 2017

Lon Chanthap

10

1 reference

Europe PubMed Central

13 August 2017

Jessica Lin

11

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Europe PubMed Central

13 August 2017

Ans Timmermans

12

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Europe PubMed Central

13 August 2017

Pascal Ringwald

14

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Europe PubMed Central

13 August 2017

Harald Noedl

15

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Europe PubMed Central

13 August 2017

Bryan Smith

16

1 reference

Europe PubMed Central

13 August 2017

Mark Fukuda

17

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Europe PubMed Central

13 August 2017

language of work or name

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publication date

6 August 2012

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Europe PubMed Central

13 August 2017

Antimicrobial Agents and Chemotherapy

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Europe PubMed Central

13 August 2017

56

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Europe PubMed Central

13 August 2017

11

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Europe PubMed Central

13 August 2017

5484-5493

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Europe PubMed Central

13 August 2017

Standardizing the measurement of parasite clearance in falciparum malaria: the parasite clearance estimator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486599

30 September 2017

Effects of artesunate on parasite recrudescence and dormancy in the rodent malaria model Plasmodium vinckei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486599

30 September 2017

Artesunate dose escalation for the treatment of uncomplicated malaria in a region of reported artemisinin resistance: a randomized clinical trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486599

30 September 2017

Pharmacokinetics and pharmacodynamics of artesunate and dihydroartemisinin following oral treatment in pregnant women with asymptomatic Plasmodium falciparum infections in Kinshasa DRC.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486599

30 September 2017

Intrahost modeling of artemisinin resistance in Plasmodium falciparum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486599

30 September 2017

Dose-dependent risk of neutropenia after 7-day courses of artesunate monotherapy in Cambodian patients with acute Plasmodium falciparum malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486599

30 September 2017

Artemisinin resistance in Cambodia: a clinical trial designed to address an emerging problem in Southeast Asia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486599

30 September 2017

Population pharmacokinetics and pharmacodynamics of artemether and lumefantrine during combination treatment in children with uncomplicated falciparum malaria in Tanzania

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486599

30 September 2017

Population pharmacokinetics of artesunate and dihydroartemisinin following single- and multiple-dosing of oral artesunate in healthy subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486599

30 September 2017

Artemisinin Resistance in Plasmodium falciparum Malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486599

30 September 2017

Evidence of Artemisinin-Resistant Malaria in Western Cambodia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486599

30 September 2017

Pharmacokinetics and tolerability of artesunate and amodiaquine alone and in combination in healthy volunteers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486599

30 September 2017

What is the objective of the mass balance study? A retrospective analysis of data in animal and human excretion studies employing radiolabeled drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486599

30 September 2017

A semiphysiological pharmacokinetic model for artemisinin in healthy subjects incorporating autoinduction of metabolism and saturable first-pass hepatic extraction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486599

30 September 2017

Oral artesunate dose-response relationship in acute falciparum malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486599

30 September 2017

A pharmacokinetic and pharmacodynamic study of intravenous vs oral artesunate in uncomplicated falciparum malaria.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486599

30 September 2017

Monotherapy with sodium artesunate for uncomplicated falciparum malaria in Thailand: a comparison of 5- and 7-day regimens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486599

30 September 2017

Multiple dose pharmacokinetics of oral artemisinin and comparison of its efficacy with that of oral artesunate in falciparum malaria patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486599

30 September 2017

Efficacy of oral and intravenous artesunate in male Tanzanian adults with Plasmodium falciparum malaria and in vitro susceptibility to artemisinin, chloroquine, and mefloquine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486599

30 September 2017

Genotyping of Plasmodium falciparum isolates by the polymerase chain reaction and potential uses in epidemiological studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486599

30 September 2017

Double blind randomised clinical trial of oral artesunate at once or twice daily dose in falciparum malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486599

30 September 2017

Clinical trial of artesunate and artemether on multidrug resistant falciparum malaria in Thailand. A preliminary report

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486599

30 September 2017

Clinical pharmacology and therapeutic potential of artemisinin and its derivatives in the treatment of malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486599

30 September 2017

A histidine-rich protein 2-based malaria drug sensitivity assay for field use.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486599

28 June 2018

Artesunate versus artemether for the treatment of recrudescent multidrug-resistant falciparum malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486599

28 June 2018

Phospholipid composition, cholesterol content and cholesterol exchange in Plasmodium falciparum-infected red cells.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486599

28 June 2018

Artemisinin (qinghaosu): the role of intracellular hemin in its mechanism of antimalarial action

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486599

28 June 2018

A simplified liquid chromatography-mass spectrometry assay for artesunate and dihydroartemisinin, its metabolite, in human plasma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486599

22 September 2018

Pharmacokinetic profiles of artesunate after single intravenous doses at 0.5, 1, 2, 4, and 8 mg/kg in healthy volunteers: a phase I study

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486599

22 September 2018

Absence of time-dependent artesunate pharmacokinetics in healthy subjects during 5-day oral administration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486599

22 September 2018

The evaluation of radiolabeled artesunate on tissue distribution in rats and protein binding in humans.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486599

22 September 2018

Recrudescence in artesunate-treated patients with falciparum malaria is dependent on parasite burden not on parasite factors.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486599

22 September 2018

Comparative pharmacokinetics and effect kinetics of orally administered artesunate in healthy volunteers and patients with uncomplicated falciparum malaria

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486599

22 September 2018

Pharmacokinetics of artemisinin and artesunate after oral administration in healthy volunteers.

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22 September 2018

The interaction of artemisinin with red cell membranes.

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22 September 2018

The interaction of artemisinin with malarial hemozoin.

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22 September 2018

Morphological changes of clefts in Plasmodium-infected erythrocytes under adverse conditions.

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22 September 2018

Selectivity properties of pores induced in host erythrocyte membrane by Plasmodium falciparum. Effect of parasite maturation.

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22 September 2018

Pharmacology and toxicology of artelinic acid: preclinical investigations on pharmacokinetics, metabolism, protein and red blood cell binding, and acute and anorectic toxicities

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12 December 2020

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Identifiers

10.1128/AAC.00044-12

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

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