In vivo treatment with interleukin 12 protects mice from immune abnormalities observed during murine acquired immunodeficiency syndrome (MAIDS). (Q36364205)

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English	In vivo treatment with interleukin 12 protects mice from immune abnormalities observed during murine acquired immunodeficiency syndrome (MAIDS).	scientific article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7964495%20AND%20SRC:MED&resulttype=core&format=json

29 October 2019

In vivo treatment with interleukin 12 protects mice from immune abnormalities observed during murine acquired immunodeficiency syndrome (MAIDS) (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7964495%20AND%20SRC:MED&resulttype=core&format=json

29 October 2019

murine acquired immunodeficiency syndrome

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Ricardo Gazzinelli

1

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29 October 2019

Herbert C. Morse

3

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29 October 2019

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N A Giese

2

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29 October 2019

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1 December 1994

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29 October 2019

Journal of Experimental Medicine

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29 October 2019

180

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29 October 2019

6

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29 October 2019

2199-2208

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7964495%20AND%20SRC:MED&resulttype=core&format=json

29 October 2019

Multiple defects of immune cell function in mice with disrupted interferon-gamma genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191803

30 September 2017

Interleukin 12 is required for the T-lymphocyte-independent induction of interferon gamma by an intracellular parasite and induces resistance in T-cell-deficient hosts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191803

30 September 2017

Recombinant interleukin 12 cures mice infected with Leishmania major

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191803

30 September 2017

Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191803

30 September 2017

Interleukin 12 and tumor necrosis factor alpha are costimulators of interferon gamma production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191803

30 September 2017

Interleukin 12 acts directly on CD4+ T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191803

30 September 2017

Functional T lymphocytes are required for a murine retrovirus-induced immunodeficiency disease (MAIDS)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191803

30 September 2017

Retroviral induction of acute lymphoproliferative disease and profound immunosuppression in adult C57BL/6 mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191803

30 September 2017

CD4+ T cells are required for development of a murine retrovirus-induced immunodeficiency syndrome (MAIDS)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191803

30 September 2017

Defective virus is associated with induction of murine retrovirus-induced immunodeficiency syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191803

30 September 2017

Retrovirus-induced murine acquired immunodeficiency syndrome: natural history of infection and differing susceptibility of inbred mouse strains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191803

30 September 2017

TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191803

30 September 2017

Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191803

30 September 2017

Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191803

30 September 2017

B cells are required for induction of T cell abnormalities in a murine retrovirus-induced immunodeficiency syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191803

30 September 2017

Lymphokine control of in vivo immunoglobulin isotype selection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191803

30 September 2017

The majority of cells infected with the defective murine AIDS virus belong to the B-cell lineage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191803

30 September 2017

Analysis of role of CD8+ T cells in resistance to murine AIDS in A/J mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191803

30 September 2017

Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191803

30 September 2017

Cloning and expression of murine IL-12

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191803

30 September 2017

Experiment and discussion on leukaemogenesis by cell-free extracts of radiation-induced leukaemia in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191803

28 June 2018

Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191803

28 June 2018

Impaired interleukin 12 production in human immunodeficiency virus-infected patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191803

28 June 2018

Interleukin 12 induces stable priming for interferon gamma (IFN-gamma) production during differentiation of human T helper (Th) cells and transient IFN-gamma production in established Th2 cell clones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191803

28 June 2018

Specific assays for cytokine production by T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191803

28 June 2018

Severe immunodeficiency disease induced by a defective murine leukaemia virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191803

28 June 2018

A unique subset of normal murine CD4+ T cells lacking Thy-1 is expanded in a murine retrovirus-induced immunodeficiency syndrome, MAIDS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191803

28 June 2018

Simultaneous depletion of CD4+ and CD8+ T lymphocytes is required to reactivate chronic infection with Toxoplasma gondii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191803

28 June 2018

Generation of B cell memory and affinity maturation. Induction with Th1 and Th2 T cell clones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191803

28 June 2018

Natural killer (NK) cell stimulatory factor increases the cytotoxic activity of NK cells from both healthy donors and human immunodeficiency virus-infected patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191803

28 June 2018

Enhancing effect of natural killer cell stimulatory factor (NKSF/interleukin-12) on cell-mediated cytotoxicity against tumor-derived and virus-infected cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191803

22 September 2018

Impaired production of lymphokines and immune (gamma) interferon in the acquired immunodeficiency syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/7964495

12 December 2020

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Generalized lymphadenopathy in homosexual men: an update of the New York experience

1 reference

https://pubmed.ncbi.nlm.nih.gov/7964495

12 December 2020

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Inhibition of B lymphocyte activation by interferon-gamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/7964495

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-proliferative effect of IFN-gamma in immune regulation. I. IFN-gamma inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones

1 reference

https://pubmed.ncbi.nlm.nih.gov/7964495

12 December 2020

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inferred from PubMed ID database lookup

Characteristics of B cell proliferation and activation in murine AIDS

1 reference

https://pubmed.ncbi.nlm.nih.gov/7964495

12 December 2020

based on heuristic

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CD4+ subset regulation in viral infection. Preferential activation of Th2 cells during progression of retrovirus-induced immunodeficiency in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7964495

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retrovirus-induced immunodeficiency in the mouse: MAIDS as a model for AIDS

1 reference

https://pubmed.ncbi.nlm.nih.gov/7964495

12 December 2020

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inferred from PubMed ID database lookup

Acute cerebral toxoplasmosis is induced by in vivo neutralization of TNF-alpha and correlates with the down-regulated expression of inducible nitric oxide synthase and other markers of macrophage activation

1 reference

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Resistance of mice deficient in IL-4 to retrovirus-induced immunodeficiency syndrome (MAIDS)

1 reference

https://pubmed.ncbi.nlm.nih.gov/7964495

12 December 2020

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inferred from PubMed ID database lookup

Restoration of HIV-specific cell-mediated immune responses by interleukin-12 in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/7964495

12 December 2020

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Effects of IL-12 on the response and susceptibility to experimental viral infections

1 reference

https://pubmed.ncbi.nlm.nih.gov/7964495

12 December 2020

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inferred from PubMed ID database lookup

Neutralization of IL-12 decreases resistance to Listeria in SCID and C.B-17 mice. Reversal by IFN-gamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/7964495

12 December 2020

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inferred from PubMed ID database lookup

Resistance to murine acquired immunodeficiency syndrome (MAIDS)

1 reference

https://pubmed.ncbi.nlm.nih.gov/7964495

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1084/JEM.180.6.2199

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7964495%20AND%20SRC:MED&resulttype=core&format=json

29 October 2019

PMC publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7964495%20AND%20SRC:MED&resulttype=core&format=json

29 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7964495%20AND%20SRC:MED&resulttype=core&format=json

29 October 2019

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