From structure to function: new insights into hepatitis C virus RNA replication (Q36366142)

13 August 2017

1 reference

title

From structure to function: new insights into hepatitis C virus RNA replication (English)

1 reference

13 August 2017

1 reference

1 reference

2

1 reference

13 August 2017

Ralf Bartenschlager

4

0 references

author name string

Nicole Appel

series ordinal

1

1 reference

PubMed ID

16407182

13 August 2017

Francois Penin

series ordinal

3

1 reference

PubMed ID

16407182

13 August 2017

language of work or name

English

0 references

publication date

30 December 2005

1 reference

Journal of Biological Chemistry

13 August 2017

1 reference

13 August 2017

281

1 reference

13 August 2017

9833-9836

1 reference

13 August 2017

15

1 reference

Novel insights into hepatitis C virus replication and persistence

13 August 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Translation initiation by factor-independent binding of eukaryotic ribosomes to internal ribosomal entry sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

A cis-acting replication element in the sequence encoding the NS5B RNA-dependent RNA polymerase is required for hepatitis C virus RNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Kissing-loop interaction in the 3' end of the hepatitis C virus genome essential for RNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Structural biology of hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

The hepatitis C virus alternate reading frame (ARF) and its family of novel products: the alternate reading frame protein/F-protein, the double-frameshift protein, and others

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Efficient initiation of HCV RNA replication in cell culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Infectious hepatitis C virus pseudo-particles containing functional E1-E2 envelope protein complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Robust hepatitis C virus infection in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Complete replication of hepatitis C virus in cell culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Production of infectious hepatitis C virus in tissue culture from a cloned viral genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Hepatitis C virus IRES RNA-induced changes in the conformation of the 40s ribosomal subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Structural roles for human translation factor eIF3 in initiation of protein synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

The crystal structure of hepatitis C virus NS3 proteinase reveals a trypsin-like fold and a structural zinc binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Specific Interaction of Hepatitis C Virus Protease/Helicase NS3 with the 3'-Terminal Sequences of Viral Positive- and Negative-Strand RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

The nonstructural protein 3 protease/helicase requires an intact protease domain to unwind duplex RNA efficiently

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

The hepatitis C viral NS3 protein is a processive DNA helicase with cofactor enhanced RNA unwinding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Periodic cycles of RNA unwinding and pausing by hepatitis C virus NS3 helicase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

A Brownian motor mechanism of translocation and strand separation by hepatitis C virus helicase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Hepatitis C virus NS3 RNA helicase domain with a bound oligonucleotide: the crystal structure provides insights into the mode of unwinding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Structure of the hepatitis C virus RNA helicase domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Molecular views of viral polyprotein processing revealed by the crystal structure of the hepatitis C virus bifunctional protease-helicase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Topology of the Membrane-Associated Hepatitis C Virus Protein NS4B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Expression of hepatitis C virus proteins induces distinct membrane alterations including a candidate viral replication complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

A nucleotide binding motif in hepatitis C virus (HCV) NS4B mediates HCV RNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

An amino-terminal amphipathic alpha-helix mediates membrane association of the hepatitis C virus nonstructural protein 5A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Structure and function of the membrane anchor domain of hepatitis C virus nonstructural protein 5A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

The NS5A protein of hepatitis C virus is a zinc metalloprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Control of PKR protein kinase by hepatitis C virus nonstructural 5A protein: molecular mechanisms of kinase regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Mutational analysis of hepatitis C virus nonstructural protein 5A: potential role of differential phosphorylation in RNA replication and identification of a genetically flexible domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Insertion of green fluorescent protein into nonstructural protein 5A allows direct visualization of functional hepatitis C virus replication complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Hepatitis C virus nonstructural protein 5A (NS5A) is an RNA-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Ser(2194) is a highly conserved major phosphorylation site of the hepatitis C virus nonstructural protein NS5A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Identification of the major phosphorylation site of the hepatitis C virus H strain NS5A protein as serine 2321

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Phosphorylation of hepatitis C virus nonstructural protein 5A modulates its protein interactions and viral RNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Enhancement of hepatitis C virus RNA replication by cell culture-adaptive mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Reduction of hepatitis C virus NS5A hyperphosphorylation by selective inhibition of cellular kinases activates viral RNA replication in cell culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

cis-acting RNA signals in the NS5B C-terminal coding sequence of the hepatitis C virus genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

De novo initiation of RNA synthesis by hepatitis C virus nonstructural protein 5B polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Structural Analysis of the Hepatitis C Virus RNA Polymerase in Complex with Ribonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Oligomeric interaction of hepatitis C virus NS5B is critical for catalytic activity of RNA-dependent RNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

A mechanism for initiating RNA-dependent RNA polymerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Membrane association of the RNA-dependent RNA polymerase is essential for hepatitis C virus RNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Identification of FBL2 as a geranylgeranylated cellular protein required for hepatitis C virus RNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Cyclophilin B is a functional regulator of hepatitis C virus RNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Down-regulation of viral replication by adenoviral-mediated expression of siRNA against cellular cofactors for hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Hepatitis C virus RNA polymerase and NS5A complex with a SNARE-like protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Interactions between viral nonstructural proteins and host protein hVAP-33 mediate the formation of hepatitis C virus RNA replication complex on lipid raft

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Human VAP-B is involved in hepatitis C virus replication through interaction with NS5A and NS5B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Disruption of hepatitis C virus RNA replication through inhibition of host protein geranylgeranylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Hepatitis C virus RNA replication is regulated by host geranylgeranylation and fatty acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

Cyclosporin A suppresses replication of hepatitis C virus genome in cultured hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R500026200

21 January 2018

Identifiers

DOI

10.1074/JBC.R500026200

1 reference

13 August 2017

1 reference

PubMed ID

16407182