HIV-induced apoptosis requires the CD4 receptor cytoplasmic tail and is accelerated by interaction of CD4 with p56lck. (Q36366175)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8551242%20AND%20SRC:MED&resulttype=core&format=json

14 October 2019

title

HIV-induced apoptosis requires the CD4 receptor cytoplasmic tail and is accelerated by interaction of CD4 with p56lck (English)

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14 October 2019

1

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14 October 2019

author name string

M Tremblay

series ordinal

2

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14 October 2019

D D Richman

series ordinal

3

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14 October 2019

language of work or name

English

0 references

publication date

1 January 1996

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Journal of Experimental Medicine

14 October 2019

published in

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14 October 2019

volume

183

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issue

1

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14 October 2019

page(s)

39-48

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HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease

14 October 2019

cites work

1 reference

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p56lck interacts via its src homology 2 domain with the ZAP-70 kinase

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Human immunodeficiency virus type 1 Nef and p56lck protein-tyrosine kinase interact with a common element in CD4 cytoplasmic tail

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Signal transduction through the CD4 receptor involves the activation of the internal membrane tyrosine-protein kinase p56lck

30 September 2017

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30 September 2017

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The lck tyrosine protein kinase interacts with the cytoplasmic tail of the CD4 glycoprotein through its unique amino-terminal domain

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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28 June 2018

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28 June 2018

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Cross-linking of T3 (CD3) with T4 (CD4) enhances the proliferation of resting T lymphocytes.

28 June 2018

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28 June 2018

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A 32-kD GTP-binding protein associated with the CD4-p56lck and CD8-p56lck T cell receptor complexes

28 June 2018

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The cytopathic effect of HIV is associated with apoptosis.

28 June 2018

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The protein tyrosine kinase p56lck inhibits CD4 endocytosis by preventing entry of CD4 into coated pits

28 June 2018

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Comparative evaluation of several DNA binding dyes in the detection of apoptosis-associated chromatin degradation by flow cytometry

28 June 2018

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28 June 2018

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28 June 2018

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Cross-linking of the T cell receptor complex with the subset-specific differentiation antigen stimulates interleukin 2 receptor expression in human CD4 and CD8 T cells

22 September 2018

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12 December 2020

Functional analysis of a cytoplasmic domain-deleted mutant of the CD4 molecule

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12 December 2020

Massive covert infection of helper T lymphocytes and macrophages by HIV during the incubation period of AIDS

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12 December 2020

Conserved cysteine residues are critical for the enzymatic function of the lymphocyte-specific tyrosine protein kinase p56lck

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12 December 2020

Random depletion of T cells that bear specific T cell receptor V beta sequences in AIDS patients

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12 December 2020

Analysis of apoptosis in lymph nodes of HIV-infected persons. Intensity of apoptosis correlates with the general state of activation of the lymphoid tissue and not with stage of disease or viral burden

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12 December 2020

The Raf-1 serine-threonine kinase is a substrate for the p56lck protein tyrosine kinase in human T-cells

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12 December 2020

Defective protein tyrosine phosphorylation and altered levels of p59fyn and p56lck in CD4 T cells from HIV-1 infected patients

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12 December 2020

Identifiers

DOI

10.1084/JEM.183.1.39

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8551242%20AND%20SRC:MED&resulttype=core&format=json

14 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8551242%20AND%20SRC:MED&resulttype=core&format=json

14 October 2019

1 reference