Both CD4+ and CD8+ T cells are essential to induce experimental autoimmune myasthenia gravis (Q36367180)

13 August 2017

Both CD4+ and CD8+ T cells are essential to induce experimental autoimmune myasthenia gravis (English)

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13 August 2017

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5

Wigzell H

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13 August 2017

7

Olsson T

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13 August 2017

4

van der Meide P

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13 August 2017

Zhang GX

1

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13 August 2017

Xiao BG

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2

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13 August 2017

Bakhiet M

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3

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13 August 2017

Link H

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6

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13 August 2017

language of work or name

English

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publication date

1 August 1996

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Journal of Experimental Medicine

13 August 2017

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13 August 2017

184

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13 August 2017

2

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13 August 2017

349-356

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Immune regulation: a new role for the CD8+ T cell

13 August 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192725

Evidence that the T cell repertoire of normal rats contains cells with the potential to cause diabetes. Characterization of the CD4+ T cell subset that inhibits this autoimmune potential

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192725

Myasthenia gravis-like syndrome induced by expression of interferon gamma in the neuromuscular junction.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192725

The functional role of CD8+ T helper type 2 cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192725

Th1 and Th2 subsets: paradigms lost?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192725

Experimental myasthenia gravis. A murine system

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192725

In vivo therapy with monoclonal anti-I-A antibody suppresses immune responses to acetylcholine receptor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192725

Region of peptide 125-147 of acetylcholine receptor alpha subunit is exposed at neuromuscular junction and induces experimental autoimmune myasthenia gravis, T-cell immunity, and modulating autoantibodies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192725

Human transforming growth factor-beta complementary DNA sequence and expression in normal and transformed cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192725

Human T-helper lymphocytes in myasthenia gravis recognize the nicotinic receptor alpha subunit

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192725

Acetylcholine receptor-reactive T and B cells in myasthenia gravis and controls

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192725

Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192725

CD8 is needed for development of cytotoxic T cells but not helper T cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192725

Functionally conformed free class I heavy chains exist on the surface of beta 2 microglobulin negative cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192725

Differential reactivity of residual CD8+ T lymphocytes in TAP1 and beta 2-microglobulin mutant mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192725

Alloreactive cytotoxic T cells can develop and function in mice lacking both CD4 and CD8.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192725

CDw60: a marker for human CD8+ T helper cells

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192725

Large scale preparation of myelin basic protein from central nervous tissue of several mammalian species

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192725

Cloning, expression, and purification of rat IFN-alpha 1.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192725

Role of the macrophage in the pathogenesis of experimental autoimmune myasthenia gravis.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192725

Molecular cloning of rat interleukin 4 cDNA and analysis of the cytokine repertoire of subsets of CD4+ T cells

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192725

Differing lymphokine profiles of functional subsets of human CD4 and CD8 T cell clones

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192725

The CD8+ T cell repertoire in beta 2-microglobulin-deficient mice is biased towards reactivity against self-major histocompatibility class I.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192725

Effect of MHC class I and CD8 cell deficiency on experimental autoimmune myasthenia gravis pathogenesis.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192725

The purification and characterization of rat gamma interferon by use of two monoclonal antibodies

22 September 2018

1 reference

12 December 2020

Immunotherapy for myasthenia gravis: a murine model

1 reference

12 December 2020

Cloning, expression, and purification of rat IFN-gamma

1 reference

12 December 2020

Specificity of the T cell immune response to acetylcholine receptor in experimental autoimmune myasthenia gravis. Response to subunits and synthetic peptides

1 reference

12 December 2020

Pathogenic mechanisms in murine autoimmune thyroiditis: short- and long-term effects of in vivo depletion of CD4+ and CD8+ cells

1 reference

12 December 2020

CD8+ T cell homing to the pancreas in the nonobese diabetic mouse is CD4+ T cell-dependent

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12 December 2020

CD4+ suppressor cells inhibit the function of effector cells of experimental autoimmune encephalomyelitis through a mechanism involving transforming growth factor-beta

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12 December 2020

Cellular infiltrate, major histocompatibility antigen expression and immunopathogenic mechanisms in cardiac myosin-induced myocarditis

1 reference

12 December 2020

Less mortality but more relapses in experimental allergic encephalomyelitis in CD8-/- mice

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12 December 2020

Regulation of antibody production by helper T cell clones in experimental autoimmune myasthenia gravis is mediated by IL-4 and antigen-specific T cell factors

1 reference

12 December 2020

T cell reactivity to acetylcholine receptor in rats orally tolerized against experimental autoimmune myasthenia gravis

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12 December 2020

Major histocompatibility complex class II gene disruption prevents experimental autoimmune myasthenia gravis

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12 December 2020

Organ-specific autoantigens induce interferon-gamma and interleukin-4 mRNA expression in mononuclear cells in multiple sclerosis and myasthenia gravis

1 reference

12 December 2020

1 reference

12 December 2020

Induction of Interferon-γ, Interleukin-4, and Transforming Growth Factor-β in Rats Orally Tolerized against Experimental Autoimmune Myasthenia Gravis

1 reference

12 December 2020

Suppression of experimental autoimmune myasthenia gravis by nasal administration of acetylcholine receptor

1 reference

12 December 2020

Depletion of CD8+ T cells suppresses the development of experimental autoimmune myasthenia gravis in Lewis rats

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12 December 2020

Induction of oral tolerance to myelin basic protein in CD8-depleted mice: both CD4+ and CD8+ cells mediate active suppression

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12 December 2020

29 Production and assay of antibodies to acetylcholine receptors

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12 December 2020

Antigen-specific interaction between T and B cells

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12 December 2020

Identifiers

DOI

10.1084/JEM.184.2.349

1 reference

13 August 2017

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13 August 2017

PubMed publication ID

8760788

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