Concerted action of androgens and mechanical strain shifts bone metabolism from high turnover into an osteoanabolic mode (Q36371008)

13 August 2017

Concerted action of androgens and mechanical strain shifts bone metabolism from high turnover into an osteoanabolic mode (English)

1 reference

13 August 2017

8

Peter Nawroth

1 reference

13 August 2017

Ute M Liegibel

1

1 reference

13 August 2017

Ulrike Sommer

2

1 reference

13 August 2017

Pascal Tomakidi

3

1 reference

13 August 2017

Ulrike Hilscher

4

1 reference

13 August 2017

Loes Van Den Heuvel

5

1 reference

13 August 2017

Rainer Pirzer

6

1 reference

13 August 2017

Joachim Hillmeier

7

1 reference

13 August 2017

Christian Kasperk

9

1 reference

13 August 2017

language of work or name

English

0 references

publication date

1 November 2002

1 reference

Journal of Experimental Medicine

13 August 2017

1 reference

13 August 2017

196

1 reference

13 August 2017

10

1 reference

13 August 2017

1387-1392

1 reference

In vitro effects of dynamic strain on the proliferative and metabolic activity of human osteoblasts.

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193981

Transcriptional regulation of a contractile gene by mechanical forces applied through integrins in osteoblasts

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193981

Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193981

Minireview: the OPG/RANKL/RANK system

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193981

Mechanical strain and estrogen activate estrogen receptor alpha in bone cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193981

Perspective: nonreproductive sites of action of reproductive hormones

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193981

Signal transduction. An arresting start for MAPK.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193981

Integrin-mediated interactions between human bone marrow stromal precursor cells and the extracellular matrix

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193981

Dynamic cell stretching increases human osteoblast proliferation and CICP synthesis but decreases osteocalcin synthesis and alkaline phosphatase activity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193981

Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193981

Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193981

Geometric control of cell life and death

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193981

Integrin-mediated activation of MAP kinase is independent of FAK: evidence for dual integrin signaling pathways in fibroblasts

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193981

Bone marrow, cytokines, and bone remodeling. Emerging insights into the pathophysiology of osteoporosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193981

Mechanotransduction Across the Cell Surface and Through the Cytoskeleton

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193981

Systemic administration of transforming growth factor-beta 2 prevents the impaired bone formation and osteopenia induced by unloading in rats

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193981

New perspectives in cell adhesion: RGD and integrins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193981

Perspectives: adhesion receptors in bone

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193981

The role of changes in mechanical usage set points in the pathogenesis of osteoporosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193981

Castrated men exhibit bone loss: effect of calcitonin treatment on biochemical indices of bone remodeling.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193981

Fibronectin and the alpha(5)beta(1) integrin are under developmental and ovarian steroid regulation in the normal mouse mammary gland

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193981

Mechanical strain stimulates osteoblast proliferation through the estrogen receptor in males as well as females

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193981

Studies of the mechanism by which androgens enhance mitogenesis and differentiation in bone cells

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193981

The mode of mechanical integrin stressing controls intracellular signaling in osteoblasts

28 June 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20021017

Low bone mass density at multiple skeletal sites, including the appendicular skeleton in amenorrheic runners.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20021017

Skeletal site-dependent expression of the androgen receptor in human osteoblastic cell populations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20021017

Stimulation of Smad1 transcriptional activity by Ras-extracellular signal-regulated kinase pathway: a possible mechanism for collagen-dependent osteoblastic differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20021017

Simulated weightlessness-induced attenuation of testosterone production may be responsible for bone loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20021017

Does body size account for gender differences in femur bone density and geometry?

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20021017

The bone-specific transcriptional regulator Cbfa1 is a target of mechanical signals in osteoblastic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20021017

Integrin expression and function on human osteoblast-like cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20021017

Resistance to unloading-induced three-dimensional bone loss in osteopontin-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20021017

A comparison of type I collagen, fibronectin, and vitronectin in supporting adhesion of mechanically strained osteoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20021017

Cell adhesion protein receptors as targets for transforming growth factor-beta action

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20021017

Integrin expression in human bone

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12438430

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1084/JEM.20021017

1 reference

13 August 2017

1 reference

13 August 2017

PubMed publication ID

12438430

1 reference