Slow [Na]i Changes and Positive Feedback Between Membrane Potential and [Ca]i Underlie Intermittent Early Afterdepolarizations and Arrhythmias. (Q36378229)

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English	Slow [Na]i Changes and Positive Feedback Between Membrane Potential and [Ca]i Underlie Intermittent Early Afterdepolarizations and Arrhythmias.	scientific article

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25 February 2020

Slow [Na]i Changes and Positive Feedback Between Membrane Potential and [Ca]i Underlie Intermittent Early Afterdepolarizations and Arrhythmias (English)

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25 February 2020

Eleonora Grandi

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25 February 2020

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25 February 2020

author name string

Yuanfang Xie

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25 February 2020

Zhandi Liao

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25 February 2020

Yohannes Shiferaw

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25 February 2020

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25 September 2015

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25 February 2020

Circulation: Arrhythmia and Electrophysiology

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25 February 2020

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25 February 2020

1472-1480

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25 February 2020

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25 February 2020

Nonequilibrium reactivation of Na+ current drives early afterdepolarizations in mouse ventricle

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Optical mapping of sarcoplasmic reticulum Ca2+ in the intact heart: ryanodine receptor refractoriness during alternans and fibrillation

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β-adrenergic stimulation activates early afterdepolarizations transiently via kinetic mismatch of PKA targets

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Dynamics of early afterdepolarization-mediated triggered activity in cardiac monolayers.

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Irregularly appearing early afterdepolarizations in cardiac myocytes: random fluctuations or dynamical chaos?

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Spatiotemporal intracellular calcium dynamics during cardiac alternans

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Arrhythmogenic consequences of intracellular calcium waves

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Synchronization of chaotic early afterdepolarizations in the genesis of cardiac arrhythmias

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Cardiac myocytes Ca2+ and Na+ regulation in normal and failing hearts.

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The dynamics of cardiac fibrillation

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The role of stochastic and modal gating of cardiac L-type Ca2+ channels on early after-depolarizations

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A mathematical treatment of integrated Ca dynamics within the ventricular myocyte.

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Cellular basis of triggered arrhythmias in heart failure

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Calcium and cardiac arrhythmias: DADs, EADs, and alternans

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Non-equilibrium gating in cardiac Na+ channels: an original mechanism of arrhythmia

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Cardiac excitation-contraction coupling

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Determinants of excitability in cardiac myocytes: mechanistic investigation of memory effect

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Action potential and contractility changes in [Na(+)](i) overloaded cardiac myocytes: a simulation study

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Early afterdepolarizations and cardiac arrhythmias

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Protein kinase inhibitor H-89 reverses forskolin stimulation of cardiac L-type calcium current

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New experimental evidence for mechanism of arrhythmogenic membrane potential alternans based on balance of electrogenic I(NCX)/I(Ca) currents

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10.1161/CIRCEP.115.003085

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25 February 2020

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