Targeting of Nrf2 induces DNA damage signaling and protects colonic epithelial cells from ionizing radiation (Q36378414)

13 August 2017

Targeting of Nrf2 induces DNA damage signaling and protects colonic epithelial cells from ionizing radiation (English)

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13 August 2017

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8

Woodring E Wright

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13 August 2017

10

Jerry W Shay

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13 August 2017

Sang Bum Kim

1

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13 August 2017

Raj K Pandita

2

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13 August 2017

Ugur Eskiocak

3

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13 August 2017

Peter Ly

4

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13 August 2017

Aadil Kaisani

5

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13 August 2017

Rakesh Kumar

6

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13 August 2017

Crystal Cornelius

7

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13 August 2017

Tej K Pandita

9

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13 August 2017

language of work or name

English

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publication date

8 October 2012

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Proceedings of the National Academy of Sciences of the United States of America

13 August 2017

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13 August 2017

109

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13 August 2017

43

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13 August 2017

E2949-55

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describes a project that uses

13 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3491493/fullTextXML

inferred from PubMed Central ID database lookup

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Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair.

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Immortalized epithelial cells derived from human colon biopsies express stem cell markers and differentiate in vitro

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Cell cycle checkpoint defects contribute to genomic instability in PTEN deficient cells independent of DNA DSB repair.

30 September 2017

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The mechanism of human nonhomologous DNA end joining

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Preclinical evaluation of targeting the Nrf2 pathway by triterpenoids (CDDO-Im and CDDO-Me) for protection from LPS-induced inflammatory response and reactive oxygen species in human peripheral blood mononuclear cells and neutrophils

30 September 2017

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30 September 2017

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The synthetic triterpenoids, CDDO and CDDO-imidazolide, are potent inducers of heme oxygenase-1 and Nrf2/ARE signaling

30 September 2017

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Involvement of human MOF in ATM function

30 September 2017

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Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

30 September 2017

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RAD51 localization and activation following DNA damage

30 September 2017

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Human Heterochromatin Protein 1 Isoforms HP1Hsα and HP1Hsβ Interfere with hTERT-Telomere Interactions and Correlate with Changes in Cell Growth and Response to Ionizing Radiation

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30 September 2017

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Inactivation of 14-3-3sigma influences telomere behavior and ionizing radiation-induced chromosomal instability

30 September 2017

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30 September 2017

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Regulation of hormone-induced histone hyperacetylation and gene activation via acetylation of an acetylase

30 September 2017

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Replicon clusters are stable units of chromosome structure: evidence that nuclear organization contributes to the efficient activation and propagation of S phase in human cells

30 September 2017

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An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

30 September 2017

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Crypt stem cell survival in the mouse intestinal epithelium is regulated by prostaglandins synthesized through cyclooxygenase-1.

30 September 2017

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30 September 2017

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Catalysis of ATP-dependent homologous DNA pairing and strand exchange by yeast RAD51 protein

30 September 2017

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The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity

30 September 2017

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Sister chromatids are preferred over homologs as substrates for recombinational repair in Saccharomyces cerevisiae

30 September 2017

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The synthetic oleanane triterpenoid, CDDO-methyl ester, is a potent antiangiogenic agent

30 September 2017

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https://api.crossref.org/works/10.1073%2FPNAS.1207718109

Homologous recombination contributes to the repair of DNA double-strand breaks induced by high-energy iron ions

21 January 2018

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Role of mammalian Rad9 in genomic stability and ionizing radiation response.

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.1207718109

XRCC3 and Rad51 modulate replication fork progression on damaged vertebrate chromosomes

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.1207718109

Heavy ion carcinogenesis and human space exploration.

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.1207718109

CDDO-Me Protects against Space Radiation-Induced Transformation of Human Colon Epithelial Cells

21 January 2018

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A METHOD FOR DETERMINING DOSE-MODIFICATION FACTORS

21 September 2018

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12 December 2020

New insights into NHEJ repair processes in prokaryotes

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12 December 2020

Oxidative stress induces H2AX phosphorylation in human spermatozoa

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12 December 2020

Inhibition of telomerase activity enhances hyperthermia-mediated radiosensitization

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12 December 2020

Devastation in Japan. Candidate radiation drugs inch forward

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12 December 2020

Effect of temperature variation on sister chromatid exchange frequency in cultured human lymphocytes

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12 December 2020

Biological Factors Affecting the Radioprotective Efficiency of S-2-[3-Aminopropylamino] Ethylphosphorothioic Acid (WR-2721). LD 50(30) Doses

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12 December 2020

Changes of deoxyribonucleoside triphosphate pools induced by hydroxyurea and their relation to DNA synthesis

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12 December 2020

Chromosomal aberration types in cells at the second division after irradiation in G1 or G2

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12 December 2020

Identifiers

DOI

10.1073/PNAS.1207718109

1 reference

13 August 2017

0 references

1 reference

13 August 2017

PubMed publication ID

23045680

1 reference