2D gel blood serum biomarkers reveal differential clinical proteomics of the neurodegenerative diseases (Q36381232)

13 August 2017

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title

2D gel blood serum biomarkers reveal differential clinical proteomics of the neurodegenerative diseases (English)

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13 August 2017

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2

Stanley H Appel

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13 August 2017

Essam A Sheta

1

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PubMed ID

16445350

13 August 2017

Ira L Goldknopf

series ordinal

3

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13 August 2017

1 February 2006

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Expert Review of Proteomics

13 August 2017

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13 August 2017

3

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13 August 2017

1

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13 August 2017

45-62

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Two-dimensional Resolution of Plasma Proteins by Combination of Polyacrylamide Disc and Gradient Gel Electrophoresis

13 August 2017

1 reference

https://api.crossref.org/works/10.1586%2F14789450.3.1.45

Mass spectrometry-based proteomics

21 January 2018

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https://api.crossref.org/works/10.1586%2F14789450.3.1.45

Proteome analysis of prostate cancer

21 January 2018

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The human plasma proteome: history, character, and diagnostic prospects

21 January 2018

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Biomarkers of neurodegenerative disorders: how good are they?

21 January 2018

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Bioinformatics strategies for proteomic profiling

21 January 2018

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Annual incidence of Alzheimer disease in the United States projected to the years 2000 through 2050.

21 January 2018

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The genetic epidemiology of neurodegenerative disease

21 January 2018

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https://api.crossref.org/works/10.1586%2F14789450.3.1.45

Epidemiology of neurodegeneration

21 January 2018

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https://api.crossref.org/works/10.1586%2F14789450.3.1.45

Molecular genetics of Alzheimer's disease.

21 January 2018

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Mutant genes responsible for Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.3.1.45

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

21 January 2018

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https://api.crossref.org/works/10.1586%2F14789450.3.1.45

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

21 January 2018

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https://api.crossref.org/works/10.1586%2F14789450.3.1.45

Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism

21 January 2018

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PINK1 mutations are associated with sporadic early-onset parkinsonism

21 January 2018

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Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology

21 January 2018

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The G6055A (G2019S) mutation in LRRK2 is frequent in both early and late onset Parkinson's disease and originates from a common ancestor

21 January 2018

1 reference

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Gene expression profiling of sporadic Parkinson's disease substantia nigra pars compacta reveals impairment of ubiquitin-proteasome subunits, SKP1A, aldehyde dehydrogenase, and chaperone HSC-70.

21 January 2018

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21 January 2018

1 reference

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Natural history of amyotrophic lateral sclerosis in a database population. Validation of a scoring system and a model for survival prediction.

21 January 2018

1 reference

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Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

21 January 2018

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Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis

21 January 2018

1 reference

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Oxidative Stress: a common denominator in the pathogenesis of amyotrophic lateral sclerosis.

21 January 2018

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Unraveling the mechanisms involved in motor neuron degeneration in ALS

21 January 2018

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Prospective study of military service and mortality from ALS.

21 January 2018

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Parkinson's disease risk factors: genetic, environmental, or both?

21 January 2018

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https://api.crossref.org/works/10.1586%2F14789450.3.1.45

The age-dependent relation of blood pressure to cognitive function and dementia

21 January 2018

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https://api.crossref.org/works/10.1586%2F14789450.3.1.45

Early complement activation increases in the brain in some aged normal subjects

21 January 2018

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https://api.crossref.org/works/10.1586%2F14789450.3.1.45

HUPO Plasma Proteome Project specimen collection and handling: towards the standardization of parameters for plasma proteome samples

21 January 2018

1 reference

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Proteomic studies of potential cerebrospinal fluid protein markers for Alzheimer's disease

21 January 2018

1 reference

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Apolipoprotein E, transthyretin and actin in the CSF of Alzheimer's patients: relation with the senile plaques and cytoskeleton biochemistry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.3.1.45

Proteomic analysis of human ventricular cerebrospinal fluid from neurologically normal, elderly subjects using two-dimensional LC-MS/MS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.3.1.45

Glycosylation changes in Alzheimer's disease as revealed by a proteomic approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.3.1.45

Evidence of oxidative stress in the neocortex in incidental Lewy body disease

21 January 2018

1 reference

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Crosslinking of alpha-synuclein by advanced glycation endproducts--an early pathophysiological step in Lewy body formation?

21 January 2018

1 reference

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Detection of N epsilon-(carboxymethyl)lysine (CML) and non-CML advanced glycation end-products in the anterior horn of amyotrophic lateral sclerosis spinal cord

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.3.1.45

Involvement of advanced glycation end-products (AGEs) in Alzheimer's disease

21 January 2018

1 reference

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Serum or cerebrospinal fluid levels of glyceraldehyde-derived advanced glycation end products (AGEs) may be a promising biomarker for early detection of Alzheimer's disease

21 January 2018

1 reference

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Proteins in human brain cortex are modified by oxidation, glycoxidation, and lipoxidation. Effects of Alzheimer disease and identification of lipoxidation targets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.3.1.45

Inflammation and the degenerative diseases of aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.3.1.45

Inflammatory process in Parkinson's disease: role for cytokines

21 January 2018

1 reference

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Reactive microglia express class I and class II major histocompatibility complex antigens in Alzheimer's disease.

21 January 2018

1 reference

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Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS.

21 January 2018

1 reference

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Activated microglia (BV-2) facilitation of TNF-alpha-mediated motor neuron death in vitro.

21 January 2018

1 reference

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Non-steroidal anti-inflammatory drugs (NSAIDs) in Alzheimer's disease: old and new mechanisms of action

21 January 2018

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Aging and proinflammatory cytokines

21 January 2018

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Role of Fcgamma receptors in nigral cell injury induced by Parkinson disease immunoglobulin injection into mouse substantia nigra

21 January 2018

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Presence of dendritic cells, MCP-1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue

21 January 2018

1 reference

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Neurofibrillary tangles of Guam parkinson-dementia are associated with reactive microglia and complement proteins.

21 January 2018

1 reference

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Decay-accelerating factor (DAF), complement receptor 1 (CR1), and factor H dissociate the complement AP C3 convertase (C3bBb) via sites on the type A domain of Bb.

21 January 2018

1 reference

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The complement system in central nervous system diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.3.1.45

Alpha-Synuclein aggregation in pathological aging and Alzheimer's disease: the impact of beta-amyloid plaque level.

21 January 2018

1 reference

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Amyloid fibril formation of alpha-synuclein is accelerated by preformed amyloid seeds of other proteins: implications for the mechanism of transmissible conformational diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.3.1.45

Astrocytes: regulation of brain homeostasis via apolipoprotein E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.3.1.45

Proteomic profiling of cerebrospinal fluid identifies biomarkers for amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.3.1.45

Cerebrospinal fluid protein patterns in neurodegenerative disease revealed by liquid chromatography-Fourier transform ion cyclotron resonance mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.3.1.45

Cerebrospinal fluid levels of free 3-nitrotyrosine are not elevated in the majority of patients with amyotrophic lateral sclerosis or Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.3.1.45

Mining biomarkers in human sera using proteomic tools

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.3.1.45

Proteomic identification of nitrated proteins in Alzheimer's disease brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.3.1.45

Aberrant expression of peroxiredoxin subtypes in neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.3.1.45

Proteomic analysis of protein oxidation in Alzheimer's disease brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.3.1.45

Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II: dihydropyrimidinase-related protein 2, alpha-enolase and heat shock cognate 71.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.3.1.45

Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part I: creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.3.1.45

Studies of potential cerebrospinal fluid molecular markers for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.3.1.45

Identification of the apolipoprotein E4 isoform in cerebrospinal fluid with preparative two-dimensional electrophoresis and matrix assisted laser desorption/ionization-time of flight-mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.3.1.45

Discovery of biomarkers in human urine and cerebrospinal fluid by capillary electrophoresis coupled to mass spectrometry: towards new diagnostic and therapeutic approaches

21 January 2018

1 reference

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A panel of cerebrospinal fluid potential biomarkers for the diagnosis of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.3.1.45

"Subcellular proteomics" of neuromelanin granules isolated from the human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.3.1.45

Proteome analysis of human substantia nigra in Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.3.1.45

alpha-synuclein gene haplotypes are associated with Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.3.1.45

Mutations in all five exons ofSOD-1 may cause ALS

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.3.1.45

Deletions of the heavy neurofilament subunit tail in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.3.1.45

21 January 2018

Identifiers

DOI

10.1586/14789450.3.1.45

1 reference

13 August 2017

1 reference

PubMed ID

16445350