Requirement of the NPXY motif in the integrin beta 3 subunit cytoplasmic tail for melanoma cell migration in vitro and in vivo. (Q36382612)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7542248%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

title

Requirement of the NPXY motif in the integrin beta 3 subunit cytoplasmic tail for melanoma cell migration in vitro and in vivo (English)

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20 October 2019

1 reference

1

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20 October 2019

author name string

P C Brooks

2

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20 October 2019

S L Deming

3

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20 October 2019

C Damsky

4

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20 October 2019

D A Cheresh

5

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20 October 2019

language of work or name

English

0 references

publication date

1 July 1995

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20 October 2019

published in

Journal of Cell Biology

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20 October 2019

volume

130

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20 October 2019

issue

2

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20 October 2019

page(s)

441-450

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Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment

20 October 2019

cites work

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Distinct functions of integrin alpha and beta subunit cytoplasmic domains in cell spreading and formation of focal adhesions.

30 September 2017

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The COOH terminus of the c-Abl tyrosine kinase contains distinct F- and G-actin binding domains with bundling activity

30 September 2017

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Effects of beta subunit cytoplasmic domain deletions on the recruitment of the integrin alpha v beta 6 to focal contacts

30 September 2017

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Single subunit chimeric integrins as mimics and inhibitors of endogenous integrin functions in receptor localization, cell spreading and migration, and matrix assembly

30 September 2017

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Crystal structure of the A domain from the alpha subunit of integrin CR3 (CD11b/CD18)

30 September 2017

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Regulation of integrin affinity states through an NPXY motif in the beta subunit cytoplasmic domain.

30 September 2017

1 reference

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Mapping of the alpha-actinin binding site within the beta 1 integrin cytoplasmic domain

30 September 2017

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Functional role of the cytoplasmic domain of the integrin alpha 5 subunit

30 September 2017

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Cell adhesion events mediated by alpha 4 integrins are essential in placental and cardiac development

30 September 2017

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Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

30 September 2017

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Receptor tyrosine kinase signaling required for integrin alpha v beta 5-directed cell motility but not adhesion on vitronectin

30 September 2017

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Specific roles of the alpha V beta 1, alpha V beta 3 and alpha V beta 5 integrins in avian neural crest cell adhesion and migration on vitronectin

30 September 2017

1 reference

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Requirement of vascular integrin alpha v beta 3 for angiogenesis

30 September 2017

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A beta turn in the cytoplasmic tail of the integrin alpha v subunit influences conformation and ligand binding of alpha v beta 3.

30 September 2017

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Targeted deletion of beta 1 integrins in F9 embryonal carcinoma cells affects morphological differentiation but not tissue-specific gene expression

30 September 2017

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A synthetic peptide from fibronectin inhibits experimental metastasis of murine melanoma cells

30 September 2017

1 reference

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Protein sequence of endothelial glycoprotein IIIa derived from a cDNA clone. Identity with platelet glycoprotein IIIa and similarity to "integrin".

30 September 2017

1 reference

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Rapid and efficient site-specific mutagenesis without phenotypic selection

30 September 2017

1 reference

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Focal adhesions: transmembrane junctions between the extracellular matrix and the cytoskeleton

30 September 2017

1 reference

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Amino acid sequence of the human fibronectin receptor

30 September 2017

1 reference

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Interaction of plasma membrane fibronectin receptor with talin--a transmembrane linkage

30 September 2017

1 reference

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Cell adhesion to fibronectin and tenascin: quantitative measurements of initial binding and subsequent strengthening response

30 September 2017

1 reference

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Integrins isolated from Rous sarcoma virus-transformed chicken embryo fibroblasts

30 September 2017

1 reference

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Novel purification of vitronectin from human plasma by heparin affinity chromatography.

30 September 2017

1 reference

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Membrane receptors for extracellular matrix macromolecules: relationship to cell adhesion and tumor metastasis

30 September 2017

1 reference

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A beta 3 integrin mutation abolishes ligand binding and alters divalent cation-dependent conformation

30 September 2017

1 reference

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Complete amino acid sequence of a novel integrin beta subunit (beta 6) identified in epithelial cells using the polymerase chain reaction

30 September 2017

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Cloning, primary structure and properties of a novel human integrin beta subunit

30 September 2017

1 reference

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Selective inhibition of integrin function by antibodies specific for ligand-occupied receptor conformers.

30 September 2017

1 reference

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cDNA sequence of the human integrin beta 5 subunit

30 September 2017

1 reference

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An interaction between alpha-actinin and the beta 1 integrin subunit in vitro

30 September 2017

1 reference

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Expression and function of chicken integrin beta 1 subunit and its cytoplasmic domain mutants in mouse NIH 3T3 cells

30 September 2017

1 reference

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Complete amino acid sequence of an integrin beta subunit (beta 7) identified in leukocytes

30 September 2017

1 reference

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30 September 2017

1 reference

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NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199943

Structure, function and biological properties of integrin ?v?3on human melanoma cells

30 September 2017

1 reference

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The cytoplasmic domain of the integrin lymphocyte function-associated antigen 1 beta subunit: sites required for binding to intercellular adhesion molecule 1 and the phorbol ester-stimulated phosphorylation site

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199943

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199943

Integrins: versatility, modulation, and signaling in cell adhesion

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199943

Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin

30 September 2017

1 reference

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A point mutation of integrin beta 1 subunit blocks binding of alpha 5 beta 1 to fibronectin and invasin but not recruitment to adhesion plaques

30 September 2017

1 reference

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Human melanoma cells derived from lymphatic metastases use integrin alpha v beta 3 to adhere to lymph node vitronectin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199943

Identification of amino acid sequences in the integrin beta 1 cytoplasmic domain implicated in cytoskeletal association

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199943

Involvement of integrin alpha V gene expression in human melanoma tumorigenicity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199943

Prediction of chain turns in globular proteins on a hydrophobic basis

30 September 2017

1 reference

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Prediction of the Secondary Structure of Proteins from their Amino Acid Sequence

30 September 2017

1 reference

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DNA sequencing with chain-terminating inhibitors

30 September 2017

1 reference

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Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function.

30 September 2017

1 reference

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Integrin beta 1- and beta 3-mediated endothelial cell migration is triggered through distinct signaling mechanisms.

28 June 2018

1 reference

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Expression of adhesion-related membrane components in adherent versus nonadherent hamster melanoma cells

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199943

Localization of an Arg-Gly-Asp recognition site within an integrin adhesion receptor

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199943

Cloning of the beta subunit of the leukocyte adhesion proteins: homology to an extracellular matrix receptor defines a novel supergene family.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199943

The Arg-Gly-Asp binding domain of the vitronectin receptor. Photoaffinity cross-linking implicates amino acid residues 61-203 of the beta subunit

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199943

Biosynthetic and functional properties of an Arg-Gly-Asp-directed receptor involved in human melanoma cell attachment to vitronectin, fibrinogen, and von Willebrand factor

28 June 2018

1 reference

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Monoclonal antibody and synthetic peptide inhibitors of human tumor cell migration

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199943

The ligand binding site of the platelet integrin receptor GPIIb-IIIa is proximal to the second calcium binding domain of its alpha subunit.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199943

Integrin (alpha v beta 3)-ligand interaction. Identification of a heterodimeric RGD binding site on the vitronectin receptor.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199943

Requirement of the integrin beta 3 subunit for carcinoma cell spreading or migration on vitronectin and fibrinogen

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199943

5-Bromo-2-deoxyuridine regulates invasiveness and expression of integrins and matrix-degrading proteinases in a differentiated hamster melanoma cell.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199943

Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinase

21 September 2018

1 reference

12 December 2020

Epidermal growth factor-induced activation and translocation of phospholipase C-gamma 1 to the cytoskeleton in rat hepatocytes

1 reference

12 December 2020

Ligand and cation binding are dual functions of a discrete segment of the integrin β3 subunit: Cation displacement is involved in ligand binding

1 reference

12 December 2020

Integrin distribution in malignant melanoma: association of the beta 3 subunit with tumor progression

1 reference

12 December 2020

Modulation of the affinity of integrin alpha IIb beta 3 (GPIIb-IIIa) by the cytoplasmic domain of alpha IIb

1 reference

12 December 2020

Identifiers

DOI

10.1083/JCB.130.2.441

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7542248%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7542248%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

1 reference