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Clinical trials in diastolic heart failure

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Epidemiology of diastolic heart failure

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The 2005 Canadian Hypertension Education Program recommendations for the management of hypertension: part 1- blood pressure measurement, diagnosis and assessment of risk.

30 September 2017

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Systematic review of multidisciplinary interventions in heart failure.

30 September 2017

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Canadian Cardiovascular Society/Canadian Heart Rhythm Society position paper on implantable cardioverter defibrillator use in Canada

30 September 2017

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Predicting and preventing adverse drug reactions in the very old.

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Characteristics and outcomes of patients hospitalized for heart failure in the United States: rationale, design, and preliminary observations from the first 100,000 cases in the Acute Decompensated Heart Failure National Registry (ADHERE).

30 September 2017

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The effect of cardiac resynchronization on morbidity and mortality in heart failure

30 September 2017

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Risk stratification for in-hospital mortality in acutely decompensated heart failure: classification and regression tree analysis

30 September 2017

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End-of-life content in treatment guidelines for life-limiting diseases

30 September 2017

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Executive summary of the guidelines on the diagnosis and treatment of acute heart failure: the Task Force on Acute Heart Failure of the European Society of Cardiology

30 September 2017

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Amiodarone or an implantable cardioverter-defibrillator for congestive heart failure

30 September 2017

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Evidence-based practice for acute decompensated heart failure

30 September 2017

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Randomized trial to determine the effect of nebivolol on mortality and cardiovascular hospital admission in elderly patients with heart failure (SENIORS).

30 September 2017

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A systematic review and meta-analysis of studies comparing readmission rates and mortality rates in patients with heart failure

30 September 2017

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Combination of isosorbide dinitrate and hydralazine in blacks with heart failure

30 September 2017

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Systematic review: cardiac resynchronization in patients with symptomatic heart failure.

30 September 2017

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The effectiveness of disease management programmes in reducing hospital re-admission in older patients with heart failure: a systematic review and meta-analysis of published reports

30 September 2017

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Multidisciplinary strategies for the management of heart failure patients at high risk for admission: a systematic review of randomized trials.

30 September 2017

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Why is depression bad for the failing heart? A review of the mechanistic relationship between depression and heart failure

30 September 2017

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Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure

30 September 2017

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Exercise training for patients with heart failure: a systematic review of factors that improve mortality and morbidity.

30 September 2017

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Keeping your patient with heart failure safe: a review of potentially dangerous medications

30 September 2017

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Heart failure with preserved left ventricular systolic function; epidemiology, clinical characteristics, and prognosis

30 September 2017

1 reference

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Effects of geriatric evaluation and management on adverse drug reactions and suboptimal prescribing in the frail elderly

30 September 2017

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Guidelines for acute decompensated heart failure treatment

30 September 2017

1 reference

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Meta-analyses of mortality and morbidity effects of an angiotensin receptor blocker in patients with chronic heart failure already receiving an ACE inhibitor (alone or with a beta-blocker).

30 September 2017

1 reference

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Exercise training meta-analysis of trials in patients with chronic heart failure (ExTraMATCH)

30 September 2017

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The Acute Decompensated Heart Failure National Registry (ADHERE): opportunities to improve care of patients hospitalized with acute decompensated heart failure

30 September 2017

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Treatment of the acute decompensation of heart failure: efficacy and pharmacoeconomics of early initiation of therapy in the emergency department

30 September 2017

1 reference

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Rate or rhythm control in persistent atrial fibrillation?

30 September 2017

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Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both

30 September 2017

1 reference

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Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function intolerant to angiotensin-converting-enzyme inhibitors: the CHARM-Alternative trial

30 September 2017

1 reference

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Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting-enzyme inhibitors: the CHARM-Added trial

30 September 2017

1 reference

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Vascular dementia: distinguishing characteristics, treatment, and prevention

30 September 2017

1 reference

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Family caregivers need support with heart failure patients

30 September 2017

1 reference

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Efficacy of angiotensin-converting enzyme inhibitors and beta-blockers in the management of left ventricular systolic dysfunction according to race, gender, and diabetic status: a meta-analysis of major clinical trials

30 September 2017

1 reference

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On the rise: The current and projected future burden of congestive heart failure hospitalization in Canada.

30 September 2017

1 reference

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The 2002/3 Canadian Cardiovascular Society consensus guideline update for the diagnosis and management of heart failure

30 September 2017

1 reference

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Incidence and preventability of adverse drug events among older persons in the ambulatory setting

30 September 2017

1 reference

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Exercise and heart failure: A statement from the American Heart Association Committee on exercise, rehabilitation, and prevention

30 September 2017

1 reference

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Current medical treatment for the exacerbation of chronic heart failure resulting in hospitalization

30 September 2017

1 reference

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Acutely decompensated heart failure: opportunities to improve care and outcomes in the emergency department

30 September 2017

1 reference

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Representation of the elderly, women, and minorities in heart failure clinical trials

30 September 2017

1 reference

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Rapid measurement of B-type natriuretic peptide in the emergency diagnosis of heart failure

30 September 2017

1 reference

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Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fraction

30 September 2017

1 reference

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New concepts in diastolic dysfunction and diastolic heart failure: Part I: diagnosis, prognosis, and measurements of diastolic function

30 September 2017

1 reference

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Left ventricular reconstruction by endoventricular circular patch plasty repair: a 17-year experience

30 September 2017

1 reference

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Long-term use of a left ventricular assist device for end-stage heart failure.

30 September 2017

1 reference

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The 2001 Canadian Cardiovascular Society consensus guideline update for the management and prevention of heart failure.

30 September 2017

1 reference

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A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure

30 September 2017

1 reference

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The mind of a failing heart: a systematic review of the association between congestive heart failure and cognitive functioning

30 September 2017

1 reference

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The EPHESUS trial: eplerenone in patients with heart failure due to systolic dysfunction complicating acute myocardial infarction. Eplerenone Post-AMI Heart Failure Efficacy and Survival Study

30 September 2017

1 reference

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Effect of carvedilol on survival in severe chronic heart failure

30 September 2017

1 reference

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Screening for cognitive impairment and dementia in the elderly

30 September 2017

1 reference

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Mechanical cardiac support 2000: current applications and future trial design: June 15-16, 2000 Bethesda, Maryland

30 September 2017

1 reference

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Long-term ACE-inhibitor therapy in patients with heart failure or left-ventricular dysfunction: a systematic overview of data from individual patients. ACE-Inhibitor Myocardial Infarction Collaborative Group

30 September 2017

1 reference

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Canadian implantable defibrillator study (CIDS) : a randomized trial of the implantable cardioverter defibrillator against amiodarone

30 September 2017

1 reference

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Caregiving as a risk factor for mortality: the Caregiver Health Effects Study

30 September 2017

1 reference

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The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators

30 September 2017

1 reference

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Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF)

30 September 2017

1 reference

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Drug-induced heart failure

30 September 2017

1 reference

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A dose-dependent increase in mortality with vesnarinone among patients with severe heart failure. Vesnarinone Trial Investigators

30 September 2017

1 reference

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Force-frequency relation in patients with left ventricular hypertrophy and failure

30 September 2017

1 reference

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Differences among geriatricians, general internists, and cardiologists in the care of patients with heart failure: a cautionary tale of quality assessment

30 September 2017

1 reference

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Bioethics for clinicians: 15. Quality end-of-life care

30 September 2017

1 reference

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A comparison of antiarrhythmic-drug therapy with implantable defibrillators in patients resuscitated from near-fatal ventricular arrhythmias

30 September 2017

1 reference

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The clinical diagnosis of heart failure in older patients

30 September 2017

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Bioethics for clinicians: 6. Advance care planning

30 September 2017

1 reference

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Congestive heart failure with normal left ventricular systolic function. Clinical approaches to the diagnosis and treatment of diastolic heart failure

30 September 2017

1 reference

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Frailty in elderly people: an evolving concept

30 September 2017

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Diagnosis and management of heart failure. Canadian Cardiovascular Society

30 September 2017

1 reference

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Effects of exercise training in patients with congestive heart failure: a critical review

30 September 2017

1 reference

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Targeted expression of transforming growth factor-beta 1 in intracardiac grafts promotes vascular endothelial cell DNA synthesis

30 September 2017

1 reference

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A clinical trial of the angiotensin-converting-enzyme inhibitor trandolapril in patients with left ventricular dysfunction after myocardial infarction. Trandolapril Cardiac Evaluation (TRACE) Study Group

30 September 2017

1 reference

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Effects of enalapril on mortality in severe congestive heart failure. Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS).

30 September 2017

1 reference

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A prospective study of delirium in hospitalized elderly

30 September 2017

1 reference

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Clarifying confusion: the confusion assessment method. A new method for detection of delirium

30 September 2017

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Sustained beneficial effect of a seventy-two hour intravenous infusion of nitroglycerin in patients with severe chronic congestive heart failure

30 September 2017

1 reference

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A comparison of enalapril with hydralazine-isosorbide dinitrate in the treatment of chronic congestive heart failure

30 September 2017

1 reference

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Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure

30 September 2017

1 reference

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Effect of oral milrinone on mortality in severe chronic heart failure. The PROMISE Study Research Group

30 September 2017

1 reference

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Alterations in left ventricular diastolic function in conscious dogs with pacing-induced heart failure

30 September 2017

1 reference

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Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. The SAVE Investigators

30 September 2017

1 reference

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Effect on survival and hospitalization of initiating treatment for chronic heart failure with bisoprolol followed by enalapril, as compared with the opposite sequence: results of the randomized Cardiac Insufficiency Bisoprolol Study (CIBIS) III.

30 September 2017

1 reference

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B-type natriuretic peptide and clinical judgment in emergency diagnosis of heart failure: analysis from Breathing Not Properly (BNP) Multinational Study

28 June 2018

1 reference

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Milrinone and dobutamine in severe heart failure: differing hemodynamic effects and individual patient responsiveness.

28 June 2018

1 reference

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Acute vasoconstrictor response to intravenous furosemide in patients with chronic congestive heart failure. Activation of the neurohumoral axis

28 June 2018

1 reference

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Improved survival of surgically treated patients with triple vessel coronary artery disease and severe angina pectoris. A report from the Coronary Artery Surgery Study (CASS) registry

28 June 2018

1 reference

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Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions

28 June 2018

1 reference

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Continuous positive airway pressure for central sleep apnea and heart failure

28 June 2018

1 reference

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The N-terminal Pro-BNP investigation of dyspnea in the emergency department (PRIDE) study.

21 September 2018

1 reference

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Impact of mitral valve annuloplasty on mortality risk in patients with mitral regurgitation and left ventricular systolic dysfunction.

21 September 2018

1 reference

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A multicenter disease management program for hospitalized patients with heart failure

21 September 2018

1 reference

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Emotional well-being in spouses of patients with advanced heart failure.

21 September 2018

1 reference

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Prophylactic use of an implantable cardioverter-defibrillator after acute myocardial infarction.

21 September 2018

1 reference

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Left ventricular reconstruction: Early and late results

21 September 2018

1 reference

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Prophylactic defibrillator implantation in patients with nonischemic dilated cardiomyopathy.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538984

The influence of age, gender, and race on the prevalence of depression in heart failure patients.

21 September 2018

1 reference

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Predicting mortality among patients hospitalized for heart failure: derivation and validation of a clinical model

21 September 2018

1 reference

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The Mini‐Cog as a Screen for Dementia: Validation in a Population‐Based Sample

21 September 2018

1 reference

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Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-Preserved Trial

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538984

The effects of cognitive impairment on mortality among hospitalized patients with heart failure.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538984

Caregiving and risk of coronary heart disease in U.S. women: a prospective study

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538984

Management of heart failure in primary care (the IMPROVEMENT of Heart Failure Programme): an international survey.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538984

Survival benefits of angiotensin-converting enzyme inhibitors in older heart failure patients with perceived contraindications

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538984

Short-term intravenous milrinone for acute exacerbation of chronic heart failure: a randomized controlled trial

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538984

Acute precipitants of congestive heart failure exacerbations

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538984

The clinical implications of cognitive impairment in elderly patients with chronic heart failure

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538984

Effect of carvedilol on outcome after myocardial infarction in patients with left-ventricular dysfunction: the CAPRICORN randomised trial

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538984

Associations of subclinical cardiovascular disease with frailty

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538984

Severity and course of delirium in medically hospitalized nursing facility residents

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538984

Meta-analysis of the implantable cardioverter defibrillator secondary prevention trials. AVID, CASH and CIDS studies. Antiarrhythmics vs Implantable Defibrillator study. Cardiac Arrest Study Hamburg . Canadian Implantable Defibrillator Study.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538984

The effect of positive pressure airway support on mortality and the need for intubation in cardiogenic pulmonary edema: a systematic review

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538984

Resuscitation preferences among patients with severe congestive heart failure: results from the SUPPORT project. Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538984

Right and left ventricular diastolic function in patients with and without heart failure: effect of age, sex, heart rate, and respiration on Doppler-derived measurements.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538984

Hospital diagnoses, Medicare charges, and nursing home admissions in the year when older persons become severely disabled.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538984

Readmission after hospitalization for congestive heart failure among Medicare beneficiaries.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538984

Diuretic efficacy of high dose furosemide in severe heart failure: bolus injection versus continuous infusion

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2538984

Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure. The Acute Infarction Ramipril Efficacy (AIRE) Study Investigators

21 September 2018

1 reference

12 December 2020

Comprehensive geriatric assessment: a meta-analysis of controlled trials

1 reference

12 December 2020

Reduction in heart failure events by the addition of a clinical pharmacist to the heart failure management team: results of the Pharmacist in Heart Failure Assessment Recommendation and Monitoring (PHARM) Study

1 reference

12 December 2020

Short versions of the geriatric depression scale: a study of their validity for the diagnosis of a major depressive episode according to ICD-10 and DSM-IV

1 reference

12 December 2020

Early outcome of mitral valve reconstruction in patients with end-stage cardiomyopathy

1 reference

12 December 2020

Illness presentation in elderly patients

1 reference

12 December 2020

A controlled trial to improve care for seriously ill hospitalized patients. The study to understand prognoses and preferences for outcomes and risks of treatments (SUPPORT). The SUPPORT Principal Investigators

1 reference

12 December 2020

Formation of nascent intercalated disks between grafted fetal cardiomyocytes and host myocardium

1 reference

12 December 2020

Influence of the force-frequency relationship on haemodynamics and left ventricular function in patients with non-failing hearts and in patients with dilated cardiomyopathy

1 reference

12 December 2020

Management of heart failure in Canadian long-term care facilities

1 reference

12 December 2020

Recommendations for exercise testing in chronic heart faliure patients

1 reference

12 December 2020

Myoblast transplantation for heart failure

1 reference

12 December 2020

Canadian guidelines for cardiac rehabilitation and atherosclerotic heart disease prevention: a summary

1 reference

12 December 2020

Enhanced myocardial angiogenesis by gene transfer with transplanted cells

1 reference

12 December 2020

ACC/AHA guidelines for the evaluation and management of chronic heart failure in the adult: executive summary

1 reference

12 December 2020

Understanding the Treatment Preferences of Seriously Ill Patients

1 reference

12 December 2020

Mitral valve surgery in the patient with left ventricular dysfunction

1 reference

12 December 2020

Cardiac resynchronization and death from progressive heart failure: a meta-analysis of randomized controlled trials

1 reference

12 December 2020

End-of-Life Care and Congestive Heart Failure

1 reference

12 December 2020

Mechanical circulatory support and cardiac transplantation

1 reference

12 December 2020

Overview of studies of exercise training in chronic heart failure: the need for a prospective randomized multicentre European trial

1 reference

12 December 2020

1 reference

12 December 2020

Regenerating functional myocardium: Improved performance after skeletal myoblast transplantation

1 reference

12 December 2020

Hospitalization of patients with heart failure: National Hospital Discharge Survey, 1985 to 1995

1 reference

12 December 2020

The Cardiac Insufficiency Bisoprolol Study II (CIBIS-II): a randomised trial

1 reference

12 December 2020

Use of a ventilatory support system (BiPAP) for acute respiratory failure in the emergency department

1 reference

12 December 2020

Use of angiotensin-converting enzyme inhibitors and variations in cognitive performance among patients with heart failure

1 reference

12 December 2020

Early versus delayed angiotensin-converting enzyme inhibition therapy in acute myocardial infarction. The healing and early afterload reducing therapy trial

1 reference

12 December 2020

Sustained hemodynamic efficacy of therapy tailored to reduce filling pressures in survivors with advanced heart failure

1 reference

12 December 2020

Effects of angiotensin-converting enzyme inhibitors and digoxin on health outcomes of very old patients with heart failure. SAGE Study Group. Systematic Assessment of Geriatric drug use via Epidemiology

1 reference

12 December 2020

Effect of aging on the incidence of digoxin toxicity

1 reference

12 December 2020

Randomized comparison of antiarrhythmic drug therapy with implantable defibrillators in patients resuscitated from cardiac arrest : the Cardiac Arrest Study Hamburg (CASH)

1 reference

12 December 2020

Marrow stromal cells for cellular cardiomyoplasty: feasibility and potential clinical advantages

1 reference

12 December 2020

To STICH or not to STICH: we know the answer, but do we understand the question?

1 reference

12 December 2020

Do elderly systolic heart failure patients benefit from beta blockers to the same extent as the non-elderly? Meta-analysis of >12,000 patients in large-scale clinical trials

1 reference

12 December 2020

Rationale and design of a randomized trial to assess the effects of beta-blocker in diastolic heart failure; Japanese Diastolic Heart Failure Study (J-DHF)

1 reference

12 December 2020

10.1016/S0828-282X(06)70237-9

Identifiers

DOI

1 reference

13 August 2017

1 reference

13 August 2017

1 reference